Effect of low-level laser therapy on postoperative pain following root canal filling with resin-based and bioceramic sealers: A double-blinded randomized clinical trial.

Context: One of the most important aspects of endodontic treatment is pain management. Studies have reported conflicting results regarding postoperative pain following obturation with different sealers. Bioceramic sealers are promising alternative to other sealers.

Short-term consequences of daily consumption of the quinoa ( Willd.) diet in normal and diabetic rats.

Background And Aim: Willd. (Quinoa) is a nutrient-dense pseudocereal with potential therapeutic benefits for metabolic disorders, including diabetes mellitus. However, the safety and efficacy of varying concentrations of dietary quinoa on metabolic and histological parameters in diabetic and non-diabetic models remain underexplored.

Therapeutic Yoga: A feasible complementary approach for glycemic control in individuals with impaired fasting glucose and elevated HbA1c.

Background: Impaired Fasting Glucose (IFG) with elevated glycated hemoglobin (HbA1c) is a key precursor to type 2 diabetes mellitus (T2DM). Although asymptomatic, IFG significantly raises the risk of developing T2DM and cardiovascular complications, emphasizing the need for early intervention. The Therapeutic Yoga Module (TYM) was designed to offer a feasible and effective remedy for improving glycemic control.

Regulation of chronic neuroinflammation through dietary herbal products.

Chronic neuroinflammation is a consequence of disease pathogenesis underlying neurological disorders at large. While the immune response that triggers inflammatory signaling cascades is unresolved, its progression could cause functional damage to neurons and glial cells, including astrocytes, microglia, and oligodendrocytes. Controlling neuroinflammatory signaling at the early stage of disease pathogenesis is critical to prevent irreversible tissue necrosis.

Correlation of autophagy and Alzheimer's disease with special emphasis on the role of phosphodiesterase-4.

Autophagy disruption is important in Alzheimer's disease (AD) as it prevents misfolded proteins from being removed, which leads to the accumulation of amyloid plaques and neurofibrillary tangles (NFTs). Restoring autophagy improves neuronal survival and cognitive function, according to experimental models. In AD models, mTOR inhibition and AMPK activation enhance synaptic plasticity and lessen learning deficits.