Publications by authors named "Ryu Takagi"
Aims: Patients with acute pulmonary edema (APE) requiring an urgent heart failure (HF) hospitalization face poor prognosis largely due to pulmonary congestion. We aimed at assessing the patterns and variations of pulmonary congestion associated with different assessments of congestion and prognosis.
Methods: This prospective study included patients with APE who underwent lung ultrasound (8-zone B-lines method) and echocardiography immediately after emergency department visit, with follow-up assessments on days 2, 3, 7, and discharge.
Background: Mineralocorticoid receptor antagonists (MRAs) are often underutilized in patients with heart failure (HF), particularly those with diabetes and/or chronic kidney disease (CKD). However, the impact of concurrent diabetes and CKD on the efficacy and safety of eplerenone in acute HF remains uncertain.
Methods: The EARLIER trial enrolled patients with acute HF, who were randomized to receive eplerenone or placebo for 6 months.
Artificial intelligence-derived left ventricular strain in echocardiography in patients treated with chemotherapy.
Int J Cardiovasc Imaging
September 2024
Global longitudinal strain (GLS) is an echocardiographic measure to detect chemotherapy-related cardiovascular dysfunction. However, its limited availability and the needed expertise may restrict its generalization. Artificial intelligence (AI)-based GLS might overcome these challenges.
View Article and Find Full Text PDFArticle Synopsis
- Fluid dynamics research suggests coronary flow reserve (CFR) can be derived from coronary artery pressure measurements, leading to the exploration of pressure-bounded coronary flow reserve (pb-CFR) against traditional CFR assessments in patients.
- A study involving 62 patients used a pressure guidewire to gather data on both pb-CFR and conventional CFR, revealing a moderate correlation between the two (r = 0.54) but significant discrepancies in agreement.
- The findings indicate that while pb-CFR shows potential for identifying patients without significant epicardial coronary artery disease, it may not reliably substitute for traditional CFR methods in certain cases, especially with patients having diffuse disease or high fractional flow reserve (FFR).
Article Synopsis
- Fractional flow reserve (FFR) and nonhyperemic pressure ratios (NHPRs) have been key in evaluating coronary stenosis, but using pressure wires for measurement can be challenging for some patients. The new vessel fractional flow reserve (vFFR) aims to provide a wire-free alternative derived from 3D angiography.* -
- A retrospective study analyzed data from 90 lesions in 74 patients to compare vFFR and NHPR in diagnosing coronary stenosis, with FFR ≤0.80 as the benchmark. Results showed vFFR had high diagnostic accuracy similar to NHPRs across various clinical conditions.* -
- The findings indicate that vFFR is effective for identifying significant coronary stenosis