Correlation analysis of thyroid function and vitamin D levels in patients with type 2 diabetes.

Background: This study investigated the association between vitamin D status and thyroid function in 1,805 adults with type 2 diabetes mellitus (T2DM) treated at a tertiary hospital between 2018 and 2024. We analyzed demographic, metabolic, and thyroid function parameters to determine whether vitamin D levels influence thyroid dysfunction in this population.

Methods: Plasma 25-hydroxyvitamin D, thyroid hormones (FT3, FT4, TSH), and autoantibodies (TPOAb, TGAb, TRAb) were measured using electrochemiluminescence.

A distinctive human fatty acid metabolism profile associated with osteoporotic patients.

Evidence indicates a relationship between osteoporosis and nutritional factors. Nevertheless, the correlation between fatty acids and bone health remains not fully elucidated. This research sought to explore the potential associations between fatty acids (FAs) and osteoporosis.

Lower dietary folate intake increases the risk of autoimmune thyroiditis.

Background: Autoimmune thyroid diseases (AITDs) are a group of organ-specific autoimmune disorders resulting from the loss of immune tolerance, with autoimmune thyroiditis (AIT) being the most common phenotype. In recent years, folate, an essential nutrient, has been associated with the onset of various autoimmune diseases. However, the relationship between dietary folate intake and AIT remains unclear.

Higher dietary zinc intake increases the risk of autoimmune thyroiditis.

Background: Autoimmune thyroiditis (AIT), encompassing Hashimoto's thyroiditis (HT), is a prevalent chronic autoimmune disorder characterized by lymphocytic infiltration and the presence of anti-thyroid antibodies. It is the primary cause of primary hypothyroidism and affects women more frequently than men. Nearly 95% of individuals with HT exhibit thyroid peroxidase antibodies or thyroglobulin antibodies.

T-cell exhaustion-related genes in Graves' disease: a comprehensive genome mapping analysis.

Background: T-cell exhaustion (Tex) can be beneficial in autoimmune diseases, but its role in Graves' disease (GD), an autoimmune disorder of the thyroid, remains unknown. This study investigated Tex-related gene expression in GD patients to discern the potential contributions of these genes to GD pathogenesis and immune regulation.

Methods: Through gene landscape analysis, a protein-protein interaction network of 40 Tex-related genes was constructed.

Effect of L. on aorta endothelial damage-associated factors in high-fat diet and streptozotocin-induced type 2 diabetic rats.

Hyperglycemia plays crucial roles in vascular disease development, including macrovascular and microvascular diseases from diabetes mellitus (DM). Our previous study demonstrated that L. (RTL) aqueous and ethanol extracts alleviate hyperglycemia and inhibit insulin resistance in diabetic rats.

Ameliorative effect of L. on hyperglycemia in type 2 diabetes mellitus and glucose uptake in mouse C2C12 myoblasts.

L. (RTL) exhibits a wide range of phytochemical activities, for example, on treatment of diabetes mellitus (DM), in Orient. There is, however, few study regarding the effect of RTL on glycemic-related homeostasis in type 2 DM (T2DM).

Effects of Maillard reaction products in a glucose-glycine alcoholic solution on antioxidative and antimutagenic activities.

Background: Marinating meat with alcohol, such as wine and beer, is a common culinary practice in cultures worldwide. In this study we use a model marination solution comprising 0.2  mol L glucose-0.

Optimal iodine supplementation during antithyroid drug therapy for Graves' disease is associated with lower recurrence rates than iodine restriction.

Objective: A relationship between iodine intake and the effectiveness of antithyroid drug (ATD) therapy for Graves' disease (GD) has been suggested, and strict restriction of iodine intake has been tried in the treatment of GD in some studies. However, it is unclear whether dietary iodine supplementation improves the prognosis of ATD therapy for GD. This study aimed to clarify whether optimal iodine supplementation during antithyroid drug therapy for GD is associated with lower recurrence rates than iodine restriction.

Visceral adiposity is significantly associated with type 2 diabetes in middle-aged and elderly Chinese women: A cross-sectional study.

Background: Previous studies suggest that visceral fat is associated with type 2 diabetes (T2D) independent of body mass index (BMI). However, epidemiological data about the relationship between visceral fat and T2D are rare in Chinese. The aim of the present study was to investigate whether visceral fat area (VFA) is associated with T2D beyond and above BMI in the Chinese population.