Publications by authors named "Ruben Verbruggen"
Biosens Bioelectron
June 2022
Article Synopsis
- Advanced biological therapies like adalimumab (ADM) are effective but expensive and can lose effectiveness over time; therapeutic drug monitoring (TDM) is suggested to optimize dosing, although it often takes a long time to get results.*
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- This study introduces a novel ADM-sensor that integrates fiber optic surface plasmon resonance (FO-SPR) and self-powered microfluidics, allowing for quick ADM monitoring directly in a doctor's office.*
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- The developed biosensor detects ADM in plasma with a limit of detection of 0.35 μg/mL and provides results in under 12 minutes, showcasing significant potential for bedside monitoring of various drugs beyond ADM in the future.*
