Supplementation with complex milk lipids during brain development promotes neuroplasticity without altering myelination or vascular density.

Background: Supplementation with complex milk lipids (CML) during postnatal brain development has been shown to improve spatial reference learning in rats.

Objective: The current study examined histo-biological changes in the brain following CML supplementation and their relationship to the observed improvements in memory.

Design: The study used the brain tissues from the rats (male Wistar, 80 days of age) after supplementing with either CML or vehicle during postnatal day 10-80.