Three previously unreported diterpenoids, -gaultheric acid (), 7-hydroxy-karamatsuic acid () and -bodinieric acid J (), along with seven known diterpenoids (), were yielded from the 95% ethanol extract of the aerial parts of Vahl. The elucidation of their structure was accomplished through integrated interpretation of physicochemical characteristics combined with multi-spectral investigations, including 1D/2D NMR, ECD and HR-ESI-MS. Anti-inflammatory activity tests were conducted on the compounds -, revealing that inhibited LDH release with an IC value of 14.
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February 2024
Three new diterpenoids, named nematocynine A-C (1-3), together with twelve known compounds (4-15) were isolated from the aerial part of Hand.-Mazz (Hereinafter referred to ). Their structures were elucidated by detailed spectroscopic analysis and comparison with literature data.
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October 2022