Min Metall Explor
April 2025
This laboratory-scale study presents the development and validation of a hydraulic fracturing technique to directly measure the tensile strength of cemented paste backfill (CPB), providing an alternative to traditional strength testing methods. Fracture initiation pressure (FIP) was used as the primary measure of CPB strength. Experimental results were compared with traditional benchmark measures such as uniaxial compressive strength (UCS), Brazilian tensile strength (BTS), and critical Mode-I fracture toughness (K).
View Article and Find Full Text PDFComputational drug repositioning has emerged as an efficient approach to discovering new indications for existing drugs, offering lower risk and cost compared to traditional drug discovery methods. Various computational approaches have been developed, including targetbased, gene-expression-based, phenome-based, and multi-omics-based methods. Recent advancements leverage diverse data sources, such as biomedical databases and online healthrelated information.
View Article and Find Full Text PDFDrug Metab Bioanal Lett
April 2025
Background: Nicotine addiction remains a significant public health challenge, driving the need for effective treatment strategies. While various pharmacological approaches have been explored, targeting neurotransmitter and neuromodulator systems offers a promising avenue. These systems, particularly those involving dopamine, play a pivotal part in interceding the rewarding effects of nicotine and the development of dependence.
View Article and Find Full Text PDFDye effluents from various sectors have constantly imperilled the environment and ecosystem. Nano-composite membrane technology incorporating metal-organic frameworks (MOFs) has shown tremendous potential for toxic pollutant remediation. This study details the impact of ZIF-67 MOF nanoparticles on the structural properties of polyvinylidene fluoride (PVDF) ultrafiltration membrane during the non-solvent induced phase separation (NIPS) process.
View Article and Find Full Text PDFThe thin film nanocomposites (TFN) based membranes are sensitive to the synergy between the polymer and nanoparticles. TFN incorporating metal-organic frameworks (MOFs) have shown tremendous enhancement in permeability. This study investigates alternate MOF positioning during TFC fabrication for a highly selective membrane.
View Article and Find Full Text PDFInt J Burns Trauma
October 2021
Introduction: Sideswipe injuries are most commonly described in passengers traveling in a car or bus, but here we report an unusual mode of sideswipe injuries, in passengers traveling in a train sitting on window seats with elbow protruding outside the window.
Case Series: Four patients reported to our Orthopaedic emergency 2 hours after a railway track accident with more or less similar pattern of injury, an open proximal forearm monteggia fracture-dislocation with bone and soft tissue loss along with closed fracture humerus, and with or without radial nerve palsy and intact distal pulses. We followed a multidisciplinary approach with initial wound lavage followed by wound debridement, stabilization of monteggia and humerus fractures with different justifiable modalities of treatment with an exploration of the radial nerve.
J Indian Soc Periodontol
January 2021
Background And Aim: Reconstruction of interdental papillae (IDP) is among the most difficult periodontal therapy. Papillary recession is multifactorial, and several surgical, nonsurgical, and minimally invasive techniques have been suggested. The purpose of this study was to evaluate the clinical application of injectable hyaluronic acid (HA) gel for the reconstruction of IDP in Nordland and Tarnow's Class I and II papillary recession cases.
View Article and Find Full Text PDFEnviron Monit Assess
January 2021
Orthosulfamuron, a rice herbicide of the family pyrimidinyl sulfonylurea, causes ground water contamination for its moderate persistence and high water solubility. It may cause phytotoxicity and, thereby, affect the growth of succeeding crops. Keeping in view of the environmental safety, the interaction between orthosulfamuron and soil fungi was investigated.
View Article and Find Full Text PDFContext: Major limitations of conventional radiography are overlapping and lack of 3D information. Surgical exposure, though being able to provide accurate information, provides very little time to plan-out the type of periodontal regeneration required during surgery. Cone Beam Computed Tomography (CBCT) has emerged as a feasible tool and found to be accurate.
View Article and Find Full Text PDFJ Clin Orthop Trauma
July 2018
A rare case of a type III Monteggia fracture equivalent with compartment syndrome is reported here. Literature is very scanty about this rare combination of injuries which we are discussing. Timely intervention can lead to a satisfactory outcome even in these complex injuries.
View Article and Find Full Text PDFReporting a rare scenario of hypoglossal nerve palsy in craniovertebral tuberculosis. Two patients presented in outpatient department with chief complaints of pain in neck, restricted neck movements, gait changes, difficulty in speech and weakness in all the extremities. On the basis of clinicoradiological correlation, the patients were diagnosedwithtuberculosis of C1-C2 spine.
View Article and Find Full Text PDFBackground: Complex distal end of humerus fractures are one of the most challenging cases in orthopedics. There is a paucity of literature on outcomes of parallel reconstruction plates using olecranon osteotomy technique along with large sample size. This study focuses primarily on rate of various complications encountered in intraarticular AO Type C distal humerus fractures.
View Article and Find Full Text PDFBackground: Four cannulated cancellous screws (CCS) in diamond configuration have been recommended by some authors for fixation of intracapsular neck of femur (ICNF) fracture with posterior comminution in adults. This is also supported by biomechanical studies. However, the clinical usefulness of this biomechanical advantage is not known.
View Article and Find Full Text PDFBackground: Comparision of results and complications of exposed versus buried Kirschner wires (K-wires) after open reduction of lateral condyle fractures is scarce and mainly from western population; hence, we envisaged to study the safety and efficacy of exposed and buried K-wires used for fixation of displaced pediatric fracture of the lateral condyle of humerus in Indian setup.
Materials And Methods: A prospective, nonrandomized, comparative study was conducted in 50 patients with age <12 years, presenting with displaced fracture of lateral condyle of humerus of <2 weeks duration, without associated ipsilateral upper limb injury, who were treated by open reduction and internal fixation with either exposed or buried K-wires ( = 25 in each group). At a minimum followup of 3 months, status of fracture reduction, union, evidence of osteomyelitis, carrying angle at the elbow, and elbow range of motion (ROM) were assessed clinicoradiologically.
Objective: Impingement syndrome is the most common differential in a patient presenting to an orthopaedic OPD with shoulder pain. Impingement syndrome is often managed with subacromial corticosteroid injection, which can be instilled using either landmark guided (LMG) approach or with the assistance of ultrasound (US). This study was envisaged to enquire whether ultrasound assistance improves the accuracy, efficacy or safety profile of the injection.
View Article and Find Full Text PDFCircadian (locomotor activity/perching) behaviour of the weaverbird (Ploceus philippinus) under different light intensities was studied. Six groups of birds were subjected to 12L:12D (L = 1000 and 10 lux and D = 0.3 lux) for two weeks, and thereafter released into constant dim illumination (LL(dim) = 0.
View Article and Find Full Text PDFThis study investigated whether changes in illumination modify perception of day and night conditions in a diurnal species, the Indian weaver bird. Birds were initially subjected to a 12-h light:12-h dark regime (12L:12D; L=20 lux, D =0.5 lux).
View Article and Find Full Text PDF