Publications by authors named "Rodrigo Machado"

Marine protected areas (MPAs) are key for biodiversity conservation and natural resource management, contributing to ecosystem services. However, fixed MPA boundaries present challenges for species with large geographic ranges, such as marine mammals. It is essential to evaluate the role of international MPA networks in protecting species like the South American sea lion (Otaria flavescens) and the Southern right whale (Eubalaena australis), whose distribution spans the southern coasts of Brazil, Uruguay, and Argentina.

View Article and Find Full Text PDF

Huanglongbing (HLB), caused mainly by Liberibacter (CLas), is a devastating disease threatening citrus production worldwide, leading to leaf mottling, fruit deformation, and significant yield losses. This study generated a comprehensive co-expression network analysis using RNA-seq data from 17 public datasets. Weighted gene co-expression network analysis (WGCNA) was applied to identify gene modules associated with citrus species, tissue types, and days post-infection (DPIs).

View Article and Find Full Text PDF
Article Synopsis
  • - This study is the first to analyze the presence of anthropogenic microparticles in franciscana dolphins, the most endangered cetaceans in the Southwest Atlantic Ocean, using samples from ten female dolphins collected between 2013 and 2023.
  • - Analysis of the intestinal content and wall tissues revealed that all samples contained anthropogenic particles, primarily in the form of fibers, with various types of polymers like polyester and polypropylene identified through advanced spectroscopic techniques.
  • - The research indicated differences in the types and colors of microplastics found in various sections of the dolphin's intestines, highlighting the extent of microplastic absorption in these endangered animals.
View Article and Find Full Text PDF

In higher plants, the shift from vegetative to reproductive development is governed by complex interplay of internal and external signals. TERMINALFLOWER1 (TFL1) plays a crucial role in the regulation of flowering time and inflorescence architecture in Arabidopsis thaliana. This study aimed to explore the function of BdRCN4, a homolog of TFL1 in Brachypodium distachyon, through functional analyses in mutant and transgenic plants.

View Article and Find Full Text PDF
Article Synopsis
  • Plastic pollution significantly impacts marine ecosystems, with microplastics entering the food chain through invertebrates and fish.
  • The study examined the diets of six fish species to determine how their feeding behaviors contribute to plastic ingestion, classifying them into various predator groups based on age and trophic interactions.
  • Results showed that fish with higher dietary overlap consumed more microplastic fibers, indicating that a broader diet may increase vulnerability to plastic ingestion, highlighting the need to understand ecological interactions to address plastic contamination effectively.
View Article and Find Full Text PDF

Gastric squamous cell carcinoma (SCC) is a rare and puzzling entity that challenges conventional paradigms of gastric malignancies, especially in young adults. This case report presents a 22-year-old male with invasive SCC of the stomach, emphasizing the rarity of such occurrences and their diagnostic challenges. The literature review underscores the scarcity of information on gastric SCC, necessitating a critical examination of its clinical implications, etiological factors, and optimal management.

View Article and Find Full Text PDF

The consequences of mass radiological events, particularly those involving the activation of a radiological dispersion device (RDD), have been extensively studied by scientific groups. However, the critical initial period of such an event, usually spanning the first 100 h, can be characterized by a scarcity of information, potentially leading to delays in mitigating strategies. In response, a research group utilized computer simulations to generate solid, conservative analytical details that can aid decision-making and guide the prioritization of initial care based on variables such as age, sex, location, and local atmospheric stability conditions.

View Article and Find Full Text PDF

•This is the first study in Brazil about diets to prepare for colonoscopy. •The normocaloric diet was not inferior to the liquid diet regarding the quality of the colonoscopy preparation. •Both diets were well tolerated, but the normocaloric diet was more accepted than the liquid diet.

View Article and Find Full Text PDF

The different combinations of molecular dynamics simulations with coarse-grained representations have acquired considerable popularity among the scientific community. Especially in biocomputing, the significant speedup granted by simplified molecular models opened the possibility of increasing the diversity and complexity of macromolecular systems, providing realistic insights on large assemblies for more extended time windows. However, a holistic view of biological ensembles' structural and dynamic features requires a self-consistent force field, namely, a set of equations and parameters that describe the intra and intermolecular interactions among moieties of diverse chemical nature (i.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of ultra-thin strut drug-eluting stents (UTS-DES) compared to thin strut stents in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
  • Results show that, initially, patients with UTS-DES experienced fewer major adverse cardiac events (MACE) and repeat revascularizations, suggesting a potential benefit.
  • However, after adjusting for other factors and using propensity score matching, the one-year incidence of MACE was similar between both groups, indicating no significant difference in clinical outcomes.
View Article and Find Full Text PDF

Purpose: Eosinophilic oesophagitis (EoE) is a chronic immune-mediated disease, and an endosonographic evaluation may help the diagnosis. The main objectives of this study were to measure the thickness of the oesophageal wall using a radial endoscopic ultrasound (EUS), mucosa/submucosa (MSM), muscularis propria (MP) and mucosa to muscularis propria (MMP); to compare these measurements between patients with and without EoE; to correlate them with the Endoscopic Reference Score (EREFS); and to evaluate the diagnostic accuracy of these measurements.

Methods: Children and adolescents (aging from 4 to 17 years) were evaluated in this prospective cross-sectional study.

View Article and Find Full Text PDF

In the present study, we investigated gender differences in personality and psychiatric correlates among adults ( = 115) seeking treatment for problematic internet use (PIU) at a specialized clinic in São Paulo, Brazil. All participants were assessed at the beginning of their treatment for co-occurring psychiatric conditions, other addictive behaviors, and personality characteristics. Women ( = 20) were more likely to present with greater rates of psychiatric comorbidity compared to men ( = ), including mood disorders, anxiety disorders, obsessive-compulsive disorder, post-traumatic stress disorder, and bulimia nervosa.

View Article and Find Full Text PDF

Coronary obstruction is an uncommon and severe complication after a transcatheter aortic valve replacement (TAVR), that occurs during the procedure in the vast majority of patients. In the present case even in the absence of classic risk factors, an acute coronary syndrome occurred one day after TAVR. Selective angiography revealed a severe left main ostium obstruction by the bulky native leaflet calcification.

View Article and Find Full Text PDF

The Covid-19 pandemic in Brazil was widely affected by politics and the population's consumption of information is fundamental to understanding the situation. This study aimed at understanding the relationship between political-ideological markers, consumption of information, and preventive practices during the pandemic. We conducted an online survey with 1,328 Brazilians who answered a questionnaire about authoritarianism, conservatism, political orientation, trust in social media, and preventive practices during the pandemic The results indicate that right-wing and centrist individuals, with higher authoritarianism or higher conservatism scores, put significantly more trust in the information about Covid-19 conveyed through WhatsApp and less trust in the information conveyed through traditional media, in comparison with left-wing individuals or individuals with low scores for these factors.

View Article and Find Full Text PDF

Plastic is one of the most commonly found residues in the marine environment, which can cause several impacts. This study evaluated the interaction of marine litter with surf-zone trammel nets in Southern Brazil. Fifty fishing operations were sampled, where 4213 items were captured: 1500 discarded fish, 1384 fragments of marine litter, and 1329 utilized fishes.

View Article and Find Full Text PDF

Objectives: Pancreatic pseudocysts (PPC) are fluid collections with a well-defined wall that persist for more than 4 weeks inside or around the pancreas as a result of pancreatic inflammation and/or a ductal lesion. PPC have been successfully treated with endoscopic ultrasound (EUS)-guided drainage using different stents. This study aimed to evaluate the safety and efficacy of EUS-guided drainage of PPC using double-pigtail plastic stents in a tertiary hospital.

View Article and Find Full Text PDF

The Solimões Formation is a southwest geological unit of the Brazilian Amazon, being well-known for the Cenozoic giant eusuchian fossils. Among the eight species of Crocodylia described for this formation, the alligatoroid Purussaurus brasiliensis is the best known worldwide due to its enormous size. The holotype was described in 1892 by Barbosa-Rodrigues, composed by a right hemimandible.

View Article and Find Full Text PDF

We present estimates of the seasonal and spatial occupation by pinnipeds of the Wildlife Refuge of Ilha dos Lobos (WRIL), based on aerial photographic censuses. Twenty aerial photographic censuses were analysed between July 2010 and November 2018. To assess monthly differences in the numbers of pinnipeds in the WRIL we used a Generalized Linear Mixed Model.

View Article and Find Full Text PDF

Three patients with eosinophilic meningitis (EoM) were investigated in two hospitals in Porto Alegre, Southern Brazil. These patients had a common exposure after the ingestion of raw mollusks in a religious ritual. Two of them had an uncommon presentation with intense lower distal extremities pain and small fiber neuropathy as defined by an electroneuromyography (ENMG) study.

View Article and Find Full Text PDF

This study describes a recreational fishing method focused on marine catfish, Genidens barbus (Endangered-EN), through the adoption of its eggs as a natural bait during its reproductive period in southern Brazilian ecosystems. Male G. barbus perform parental care, collecting eggs released by females after the fertilization process.

View Article and Find Full Text PDF

Background: Scientific advances have improved longevity in cystic fibrosis (CF) patients and many of these patients can expect to experience age-related gastrointestinal co-morbidities. We aimed to assess the extent to which age might impact gastroesophageal reflux (GER) in patients with CF.

Methods: Our esophageal pH-multichannel intraluminal impedance monitoring database was searched for tracings belonging to CF patients ≥2 years old without prior fundoplication and not taking anti-reflux medications immediately prior (within 7 days) and during the study.

View Article and Find Full Text PDF

 Telecytopathology (TCP) may allow proper and timely evaluation of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) specimens. The aim of this study was to evaluate the feasibility of TC through a multiplatform instant messenger smartphone application to evaluate specimens of EUS-FNA of pancreatic solid lesions.  Twenty-three patients (14 male/9 female; median age: 56 yr.

View Article and Find Full Text PDF

 Translated and validated outcome instruments are of great importance, since they can be used for researchers studying different populations with the same problem. The objective of the present study was to translate, culturally adapt and validate the Hip Disability and Osteoarthritis Outcome Score (HOOS) into Brazilian Portuguese.  The HOOS was translated from English into Brazilian Portuguese, translated back into English, and submitted to an experts committee.

View Article and Find Full Text PDF

One of the most recognized anthropogenic impacts in marine environments is solid waste pollution, especially plastic, which can be ingested by fish, thus interfering with their health. In this context, the aim of this study is to describe the ingestion of plastic fragments and to identify the possible effect of this contamination in the condition factor of Genidens genidens in the Laguna Estuarine System. The stomach contents of 92 G.

View Article and Find Full Text PDF

Tuberculosis patients taking second line drugs such as ethionamide (ETH) have often experienced previous treatment failure and usually have a complex history of disease and treatment that can span decades. Mutations in the ETH activating enzyme, EthA, confer resistance through undescribed mechanisms. To explore the impact of EthA mutations on ETH resistance, data from a total of 160 ETH isolates was analysed.

View Article and Find Full Text PDF