Small Molecule Interactions with Biomacromolecules: DNA Binding Interactions of a Manganese(III) Schiff Base Complex with Potential Anticancer Activities.

A manganese(III) complex, [Mn(L)(SCN)(enH)](NO)·HO () (HL = 2-(()-(2-(()-2-hydroxy-3-methoxybenzylidene-amino)-ethyl-imino)methyl)-6-methoxyphenol), has been synthesized and characterized by single-crystal X-ray diffraction analysis. The interaction of with DNA was studied by monitoring the decrease in absorbance of the complex at λ = 324 nm with the increase in DNA concentration, providing an opportunity to determine the binding constant of the --DNA complex as 5.63 × 10 M.

Self-Assembly of Octanuclear Pt/Pd Coordination Barrels and Uncommon Structural Isomerization of a Photochromic Guest in Molecular Space.

Two tetragonal molecular barrels and were successfully synthesized by coordination-driven self-assembly of a tetrapyridyl donor () of the thiazolo[5,4-]thiazole backbone with -blocked 90° Pd(II) and Pt(II) acceptors, respectively. The single-crystal structure analysis of revealed the formation of a two-face opened tetragonal Pd molecular barrel architecture. In contrast, the isostructural Pt(II) barrel () is water-soluble.

Slow Magnetic Relaxation in a Co Dy Trimer and a Co Dy Tetramer.

The combination of Co(III) and Dy(III) with a compartmental Schiff base ligand (H L=3-[(2-Hydroxy-3-methoxy-benzylidene)-amino]-propane-1,2-diol), presenting three different coordinating pockets, has allowed the synthesis of two novel Co(III)-Dy(III) complexes: [Co Dy(HL) ]NO  ⋅ 2CH CN (1), a rare example of trinuclear linear Co Dy complex (and the first with slow relaxation of magnetization in absence of a DC field) and [Co Dy (μ -OH) (HL) (OAc) ] ⋅ 4.6H O (2), the first tetranuclear Co Dy cluster with a rhomb-like structure where the Co(III) ions are connected along the short diagonal of the rhomb. 1 presents two different relaxation processes: a fast relaxation dominated by Quantum tunnelling (QT) and a slow relaxation with an energy barrier of 40 K.

Slow magnetic relaxation and water oxidation activity of dinuclear CoCo and unique triangular CoCoCo mixed-valence complexes.

Construction of efficient multifunctional materials is one of the greatest challenges of our time. We herein report the magnetic and catalytic characterization of dinuclear [CoIIICoII(HL1)2(EtOH)(H2O)]Cl·2H2O (1) and trinuclear [CoIIICoII2(HL2)2(L2)Cl2]·3H2O (2) mixed valence complexes. Relevant structural features of the complexes have been mentioned to correlate with their magnetic and catalytic properties.

Self-assembly of a "cationic-cage" via the formation of Ag-carbene bonds followed by imine condensation.

A new strategy for the synthesis of a "cationic-cage" (CC-Ag) has been developed via metal-carbene (M-CNHC) bond formation followed by imine bond condensation. Reaction of a trigonal trisimidazolium salt H3L(PF6)3 functionalized with three flexible N-phenyl-aldehyde pendants with silver oxide yielded a trinuclear tricationic organometallic cage (OC-Ag). Subsequent treatment of the organometallic cage (OC-Ag) with 1,4-diaminobutane links the two tris-NHC ligands via imine bond condensation, which thus generates a 3D 'cationic-cage' (CC-Ag).

A Schiff base platform: structures, sensing of Zn(ii) and PPi in aqueous medium and anticancer activity.

A reaction of N,N-bis(3-methoxysalicylidene) diethylenetriamine (H2Vd) and Zn(NO)·6HO, ZnBr, ZnI and Cd(NO)·4HO in a methanol solution led to zinc and cadmium complexes of different nuclearities, [Zn(Vd·H)(X)]·CHOH (X = NO, Br, I) [1a, 1b and 1c] and Cd(Vd)(NO) (2). In 1(a-c), two H2Vd ligands bridge the two metal centers whereas in 2, they provide sideways support to two terminal Cd ions, providing an all-oxygen envelope to the central Cd ion. All four compounds were characterized by elemental analysis, FT-IR spectroscopy and single crystal X-ray diffraction analysis.

Co, Co, and a Series of CoLn (Ln = Nd, Sm, Gd, Tb, Dy) Coordination Clusters: Search for Single Molecule Magnets.

We report herein the syntheses and investigation of the magnetic properties of a Co compound, a series of trinuclear CoLn (Ln = Nd, Sm, Gd, Tb, Dy) complexes, and a Co complex. The homometallic Co core was obtained from the reaction of Ln(NO)·xHO/Co(NO)·6HO/Hvab/EtN in a 0.5:0.

Heterometallic Cu(II)-Dy(III) Clusters of Different Nuclearities with Slow Magnetic Relaxation.

The synthesis, structures, and magnetic properties of two heterometallic Cu(II)-Dy(III) clusters are reported. The first structural motif displays a pentanuclear Cu(II)4Dy(III) core, while the second one reveals a nonanuclear Cu(II)6Dy(III)3 core. We employed o-vanillin-based Schiff base ligands combining o-vanillin with 3-amino-1-propanol, H2vap, (2-[(3-hydroxy-propylimino)-methyl]-6-methoxy-phenol), and 2-aminoethanol, H2vae, (2-[(3-hydroxy-ethylimino)-methyl]-6-methoxy-phenol).

Doubly chloro bridged dimeric copper(II) complex: magneto-structural correlation and anticancer activity.

We have synthesized and structurally characterized a new doubly chloro bridged dimeric copper(II) complex, [Cu2(μ-Cl)2(HL)2Cl2] (1) based on a Schiff base ligand, 5-[(pyridin-2-ylmethylene)-amino]-pentan-1-ol). Single crystal X-ray diffraction shows the presence of dinuclear copper(II) centres in a square pyramidal geometry linked by obtuse double chloro bridge. The magnetic study illustrated that weak antiferromagnetic interactions (J = -0.

Bis{2-[(5-hy-droxy-pent-yl)imino-meth-yl]phenolato-κ(2) N,O (1)}copper(II).

In the title compound, [Cu(C12H16NO2)2], the Cu(II) ion, located on a center of inversion, is coordinated by two singly deprotonated Schiff base ligands derived from condensation of salicyldehyde and 1-amino-pentan-5-ol. The imino N and phenol O atoms from both ligands offer a square-planar arrangement around the metal ion. The Cu-N and Cu-O bond lengths are 2.