Optical coherence tomography angiography measurements in thyroid eye disease: A systematic review and meta-analysis.

Thyroid eye disease (TED) is defined as a common ocular manifestation of graves' disease, which affects the dynamics of the retinal vessels by various autoimmune and mechanical ways. Herein, we evaluate the retinal microvascular alterations in TED subjects using optical coherence tomography angiography (OCTA). PubMed, Scopus and Web of Sciences were systematically searched for relevant studies assessing OCTA measurements in TED patients and healthy controls.

Diagnostic and clinical utility of ultrasound elastography for uterine cervical neoplasms-a comprehensive systematic review and meta-analysis.

Purpose: Cervical cancer remains a major burden, especially in low-resource settings, due to limited screening. Traditional diagnostic tools, like colposcopy, are operator-dependent and often lack accuracy. Ultrasound elastography, including strain elastography (SE) and shear wave elastography (SWE), is a cost-effective, non-invasive tool for assessing tissue stiffness, aiding in distinguishing benign from malignant cervical lesions, and monitoring treatment.

Comparative risk of cancer associated with SGLT inhibitors and DPP-4 inhibitors in patients with diabetes: a systematic review and meta-analysis.

Aims: This systematic review and meta-analysis aimed to compare the overall and site-specific cancer risk associated with SGLT2i versus DPP4i in patients with type 2 diabetes mellitus.

Methods: We systematically searched PubMed, Scopus, and Web of Science for cohort studies comparing cancer incidence in adult type 2 diabetes patients treated with SGLT2i versus DPP4i. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model due to significant heterogeneity (I²).

Short-term efficacy of peripheral nerve stimulation for essential tremor in a randomized double-blind controlled trial.

Peripheral nerve stimulation (PNS) demonstrates promise for some neurological conditions. However, its effectiveness for essential tremor (ET) requires further research. In this randomized, double-blind, sham-controlled trial, we investigated the safety and efficacy of a single, 40-minute PNS session in ET.

OCTA measurements in Behcet's disease across different stages of the disease activity: A systematic review and meta-analysis.

Purpose: Behcet disease (BD) is an autoimmune disease characterized by diffuse all-sized obliterative vasculitis, thrombotic vasculopathy, and common ocular involvement. This study aims to evaluate the retinal microvascular alterations in BD using optical coherence tomography angiography (OCTA).

Methods: PubMed, Embase, and Web of Sciences were systematically searched for relevant studies assessing OCTA measurements in BD and healthy controls (HCs).

Human metapneumovirus (hMPV) in 2025: emerging trends and insights from community and hospital-based respiratory panel analyses-a comprehensive review.

Human metapneumovirus (hMPV) is a significant respiratory pathogen, primarily impacting young, elderly, and immunocompromised populations. While the clinical presentations are similar to those of other respiratory viruses such as respiratory syncytial virus (RSV), influenza, and SARS-CoV-2, they can still lead to serious complications. The virus primarily transmits via respiratory droplets, with outbreaks peaking during winter and spring.

Monocytic TLR4 expression and activation in schizophrenia: A systematic review and meta-analysis.

Background: The role of toll-like receptor 4 (TLR4) in schizophrenia remains unclear, with studies reporting conflicting results on its expression and activation in persons with schizophrenia (PwSCZ). This systematic review/meta-analysis compared basal monocytic TLR4 expression, as well as its activation pattern between PwSCZ and healthy controls (HCs).

Methods: This study was registered with PROSPERO (CRD42021273858) and adhered to the PRISMA guidelines.

Ultrasound evaluation of gallbladder wall thickness for predicting severe dengue: a systematic review and meta-analysis.

Background: The prevalence of dengue fever (DF), a mosquito-borne viral disease, is rising worldwide. Its severe manifestations like thrombocytopenia and plasma leakage are associated with increased mortality. Ultrasound-detected gallbladder wall thickening (GBWT) has been suggested as a potential indicator of the severity of the disease.

Current advances and challenges in mpox vaccine development: a global landscape.

Given the surge in mpox outbreaks in 2022 and the advancements in domestic and international vaccine research, the effectiveness of smallpox vaccines in providing cross-protection against mpox remains crucial. Having learned from the COVID-19 pandemic, it is significant to continue evaluating existing vaccines to ensure their safety and efficacy. Developing new vaccines for widespread use against mpox and its emerging strains also serves as a preventive strategy in the ongoing battle against this dynamic infection.

Subconjunctival dirofilariasis in a healthy subject: a case report.

Purpose: To report a case of subconjunctival dirofilariasis presenting as an inflammatory mass-like lesion in a healthy individual.

Case Presentation: A 20-year-old male with a recent history of wildlife exposure in a rural village presented with an inflammatory subconjunctival mass in his left eye. The lesion was surgically excised, and histopathological examination confirmed the presence of an immature nematode of Dirofilaria immitis.

A case report of pediatric-onset MS associated uveitis.

Background: To report a case of Pediatric-onset MS associated uveitis managed with local and systemic medications.

Case Presentation: An 11-year-old boy who was diagnosed with Pediatric-onset MS (POMS) with the first presentation of left optic neuritis in another center, was referred to our clinic with the complaint of non-improved vision in the left eye despite receiving IV 5gr methylprednisolone. After the ophthalmologic examinations, the patient was diagnosed as bilateral POMS-associated intermediate uveitis, and local treatment with corticosteroid was administered to both eyes.

Micro RNAs as a Diagnostic Marker between Glioma and Primary CNS Lymphoma: A Systematic Review.

Differentiating glioma from primary central nervous system lymphoma (PCNSL) can be challenging, and current diagnostic measures such as MRI and biopsy are of limited efficacy. Liquid biopsies, which detect circulating biomarkers such as microRNAs (miRs), may provide valuable insights into diagnostic biomarkers for improved discrimination. This review aimed to investigate the role of specific miRs in diagnosing and differentiating glioma from PCNSL.

Designing a non-hazardous nano-carrier based on graphene oxide@Polyaniline-Praseodymium (III) for fabrication of the Active/Passive anti-corrosion coating.

In this work, graphene oxide (GO) based nano-platforms were applied as a non-hazardous solid container with high encapsulating capacity and controllable release activity of eco-friendly inhibitor. For the first time, the adsorption and release properties of the praseodymium cations (Pr) on GO nanosheets functionalized with polyaniline (PANI) were investigated. The Pr cations adsorption/desorption capacity of GOPANI nano-sheets was assessed by Inductively Coupled Plasma (ICP), X-ray photoelectron spectroscopy (XPS), Field Emission Scanning Electron Microscopy (FE-SEM), and High-resolution transmission electron microscopy (HR-TEM) techniques.