Background: Substance abuse poses significant health and societal burdens, particularly among psychiatric populations. Various coping styles, such as emotion-oriented and task-oriented approaches, influence substance use behaviors. This study explores the relationship between these coping styles and the utilization and misuse of industrial and traditional substances among hospitalized psychiatric patients in Iran.
View Article and Find Full Text PDFBackground Context: Despite advances in the medical, surgical and rehabilitation treatment of spinal cord injury (SCI), there remains a need to develop therapeutic strategies to address mechanisms of secondary injury. Numerous preclinical studies have investigated the efficacy of deferoxamine, an iron chelating agent, in improving functional outcomes in SCI models. Anti-inflammatory, anti-ferroptosis, and lipoperoxidation inhibitory mechanisms have been proposed as the underlying mechanisms of action.
View Article and Find Full Text PDFBackground And Aims: Radiofrequency ablation (RFA) has emerged as a promising minimally invasive technique for eliminating intraepithelial neoplasia (IEN). We reviewed current evidence investigating the role of RFA in managing different types of IEN.
Methods: A systematic review was conducted to assess the current evidence for the use of RFA in managing various types of IEN.
Graefes Arch Clin Exp Ophthalmol
June 2025
Purpose: The widespread adoption of digital screens has raised concerns about potential impacts on ocular health, particularly intraocular pressure (IOP). This systematic review and meta-analysis aimed to examine the association between digital screen use and changes in IOP.
Methods: We conducted a comprehensive search across multiple electronic databases through January 2024, and reported adhering to PRISMA guidelines.
BMC Psychiatry
June 2025
Background: Obsessive-Compulsive Disorder (OCD) involves persistent, intrusive thoughts and repetitive behaviors. While SSRIs like escitalopram are common treatments, some patients do not respond adequately. This study aims to assess memantine's effectiveness as an adjunct therapy to enhance executive function in OCD patients.
View Article and Find Full Text PDFObjective: This study reviews the effect of the timing of intracranial pressure (ICP) monitor placement on mortality and length of hospital and intensive care unit stay outcomes.
Methods: This systematic review and meta-analysis adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, searching 3 databases for English-language studies on traumatic brain injury (TBI) and ICP monitoring up to November 2024. The PECO framework defined eligibility criteria, focusing on patients with TBI, timing of ICP placement, and various outcomes.
Introduction: Cancer patients frequently experience insomnia, adversely affecting their quality of life. This study aimed to systematically review and analyse the effectiveness and safety of acupressure and acupuncture in improving sleep quality among cancer patients suffering from insomnia, providing evidence for non-pharmacological treatment options.
Methods: Several digital databases (Scopus, PubMed, Embase, Web of Science, Medline, Cochrane library, PsycINFO, CINAHL complete, and Google Scholar) were examined for English-language records.
J Affect Disord
October 2025
Background: Bipolar disorder (BD) involves severe mood swings, particularly manic episodes. While antipsychotics like olanzapine are common treatments, adjunct therapies are necessary to improve effectiveness and reduce side effects. This study investigates the safety and efficacy of levetiracetam, an anticonvulsant, as an adjunct treatment for acute mania in BD patients.
View Article and Find Full Text PDFIntroduction: Depression is a prevalent mental health disorder with significant societal impact and treatment challenges. Recent research on the gut-brain axis has led to interest in probiotics, synbiotics, and prebiotics as potential therapeutic options for depression. This systematic review aims to evaluate their effects and provide evidence-based insights for future research and clinical practice.
View Article and Find Full Text PDFBackground: Chronic rhinosinusitis with nasal polyposis (CRSwNP) causes inflammatory nasal polyps, with an unknown cause. CRSwNP patients face a higher relapse risk, impacting their quality of life. This study assesses omalizumab's efficacy in reducing nasal polyp recurrence, aiming to provide insights into managing CRSwNP and improving patient outcomes through potential therapeutic interventions.
View Article and Find Full Text PDFBackground: Transcranial direct current stimulation (tDCS) is gaining traction for treating obsessive-compulsive disorder (OCD), but its effectiveness and safety remain uncertain. A systematic review of randomized controlled trials (RCTs) will assess its clinical benefits for symptom reduction.
Methods: Six databases-Scopus, PubMed, Web of Science, Cochrane, PsycINFO, and Cochrane Central-were searched to identify relevant studies.
Purpose: This systematic review and meta-analysis aimed to assess the changes in retinal layer thickness and vascular density in patients diagnosed with keratoconus (KC).
Methods: We conducted a thorough search in PubMed, Scopus, Embase, and Web of Science, encompassing all observational studies from January 1990 to February 2024. We analyzed the data using STATA software 17 and the random effects model with the restricted maximum likelihood (REML) or maximum likelihood (ML) method to pool the standardized mean difference (SMD) and the weighted mean difference (WMD) of retinal thickness and vascular density compared to non-KC eyes.
Case Rep Gastrointest Med
December 2024
Esophageal embryonal rhabdomyosarcoma (ERMS), a rare pediatric cancer, mimicked achalasia in a case involving dysphagia and vomiting. Diagnosis and chemotherapy necessitate careful monitoring due to potential complications. A 12-year-old girl with no prior medical history presented with progressive dysphagia and vomiting.
View Article and Find Full Text PDFFront Public Health
December 2024
Background: Keratoconus (KC) is a chronic corneal disease that typically presents in early adulthood, and may potentially result in poor mental health in affected individuals. The evidence regarding the association of depression with KC is controversial. Hence, we investigated the association between depression and KC via a systematic review and meta-analysis.
View Article and Find Full Text PDFThe efficacy of opportunistic osteoporosis screening with computed tomography (CT) scans obtained for other indications has not yet been implemented by the current guidelines. We aimed to compile available evidence on the efficacy of osteoporosis screening with CT scans obtained for other indications compared with dual X-ray absorptiometry (DXA). Studies comparing the diagnostic performance of the CT scan with the DXA published before 2023 were retrieved.
View Article and Find Full Text PDFIntroduction: Cannabinoids, both natural and synthetic, are a subject of scientific interest. Cannabis is widely used, and its impact on health and the immune system is being studied. The endocannabinoid system influences inflammation, including the Neutrophil-to-Lymphocyte Ratio (NLR), a potential diagnostic tool.
View Article and Find Full Text PDFBackground: The utilization of complementary and alternative medicine (CAM) is experiencing a global surge, accompanied by the adoption of national CAM policies in numerous countries. Traditional Persian medicine (TPM) is highly used as CAM in Iran, and the ongoing scientific evaluation of its interventions and the implementation of evidence-based medicine (EBM) encounters various barriers. Therefore, comprehending the characteristics and interactions of stakeholders is pivotal in advancing EBM within TPM policies.
View Article and Find Full Text PDFBackground: Nasal surgeries, addressing anatomical variations for form and function, require careful anesthesia administration, including dexmedetomidine and remifentanil. This meta-analysis evaluates their safety and efficacy variations in nasal surgeries, emphasizing patient comfort and optimal outcomes.
Methods: Four electronic databases (PubMed, Scopus, Web of Science, and CINAHL Complete) were searched for records in English.
J Integr Complement Med
November 2024
Primary dysmenorrhea is a common gynecological disorder that affects many women of reproductive age. Ginger, a widely used spice with anti-inflammatory properties, has been suggested as a potential treatment for the painful cramps associated with this condition. The aim of this systematic review and meta-analysis was to evaluate the efficacy of ginger for pain management in primary dysmenorrhea.
View Article and Find Full Text PDFBackground: The prevalence of tobacco use among various cancer types in Iran remains a significant concern, necessitating a comprehensive analysis to understand the extent and patterns of consumption. This study aimed to systematically review and analyze existing literature to delineate the prevalence of tobacco use across different cancer types in Iran, thereby providing a robust basis for future interventions and policy formulations.
Methods: Adhering to the PRISMA guidelines, we conducted a systematic review and meta-analysis of literature available in PubMed and Scopus databases.
Introduction: Cancer is one of the leading causes of mortality in the world which imposes numerous psychological burdens on the patients. Psycho-spiritual interventions such as meaning-based therapies may help decrease these challenges. This systematic review and meta-analysis aim to investigate the effects of meaning-based psychotherapy on post-traumatic growth and death anxiety of patients with cancer.
View Article and Find Full Text PDFBackground: Catatonia presents itself as a complex neuropsychiatric syndrome, giving rise to various motor, speech, and behavioral challenges. It is noteworthy that approximately 10% of psychiatric hospital admissions can be attributed to this condition. It is imperative to note that cannabis-induced catatonia, while infrequent, has been linked to the use of marijuana.
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