Publications by authors named "Ranjit D Singh"
Article Synopsis
- Traumatic brain injury (TBI) is a significant health issue, particularly in low- and middle-income countries like India, which presents different epidemiological trends and care practices compared to Europe.
- Data from studies in India (CINTER-TBI) and Europe (CENTER-TBI) reveal that patients in India tend to be younger and more severely injured than those in Europe, with falls being the main cause in Europe and traffic incidents in India.
- Access to pre-hospital care is markedly higher in Europe, with Indian patients more likely to receive certain surgical interventions for severe TBI, indicating differences in acute care responsiveness between the regions.
Article Synopsis
- Researchers wanted to see if it’s better to do brain surgery (called cranioplasty) right away or later after a different brain surgery (decompressive craniectomy) for people who got hurt on the head.
- They looked at data from over 5,000 patients and found that whether the cranioplasty was done early (within 90 days) or delayed (after 90 days), the people felt about the same 12 months later in terms of recovery and quality of life.
- However, those who had early cranioplasty were more likely to have a condition called hydrocephalus, which is when fluid builds up in the brain.
Early surgery versus conservative treatment in patients with traumatic intracerebral hematoma: a CENTER-TBI study.
Acta Neurochir (Wien)
November 2023
Article Synopsis
- This study looked at whether doing surgery early is better than just treating patients with trauma-related brain bleeding (t-ICH) without surgery.
- They checked the results of 367 patients, where some had surgery and others didn't, to see how well they recovered after 6 months.
- The study found that early surgery might help people with certain types of injuries, but for milder injuries, not having surgery seemed to work better.
Article Synopsis
- A recent study called RESCUE-ASDH looked at two types of brain surgeries for treating a specific brain injury called acute subdural hematoma (ASDH).
- The research included data from many hospitals across Europe and Israel, tracking how often each surgery was used and the outcomes for patients over a few years.
- Results showed that there was a big difference among hospitals in how often they chose to use decompressive craniectomy (DC) compared to craniotomy, with some hospitals using DC for a lot of their patients, while others used it much less.
Article Synopsis
- The study looked at two ways to treat a serious brain injury called acute subdural haematoma: one where doctors do surgery right away and another where they wait and try other treatments first.
- Researchers included a lot of patients (1,407) and checked how well each treatment worked over six months.
- They found that only some patients had surgery right away (24%), and the choice of treatment varied a lot between different hospitals.
Background: Investigating neurosurgical interventions for traumatic brain injury (TBI) involves complex methodological and practical challenges. In the present report, we have provided an overview of the current state of neurosurgical TBI research and discussed the key challenges and possible solutions.
Methods: The content of our report was based on an extensive literature review and personal knowledge and expert opinions of senior neurosurgeon researchers and epidemiologists.
Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (RESET-ASDH trial): study protocol for a pragmatic randomized controlled trial with multicenter parallel group design.
Trials
March 2022
Background: The rapidly increasing number of elderly (≥ 65 years old) with TBI is accompanied by substantial medical and economic consequences. An ASDH is the most common injury in elderly with TBI and the surgical versus conservative treatment of this patient group remains an important clinical dilemma. Current BTF guidelines are not based on high-quality evidence and compliance is low, allowing for large international treatment variation.
View Article and Find Full Text PDFLong-term outcome after severe traumatic brain injury: a systematic literature review.
Acta Neurochir (Wien)
March 2022
Background: Expectation of long-term outcome is an important factor in treatment decision-making after severe traumatic brain injury (sTBI). Conclusive long-term outcome data substantiating these decisions is nowadays lacking. This systematic review aimed to provide an overview of the scientific literature on long-term outcome after sTBI.
View Article and Find Full Text PDFBackground: White cord syndrome is an extremely rare complication of cervical decompressive surgery, characterized by serious postoperative neurological deficits in the absence of apparent surgical complications. It is named after the characteristic ischemic-edematous intramedullary T2-hyperintense signal on postoperative magnetic resonance imaging and is believed to be caused by ischemic-reperfusion injury. Neurological deficits typically manifest immediately after surgery, and delayed occurrence has been reported only once.
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