Publications by authors named "Ramzy P Issa"

Purpose: This scoping review has two primary aims: (1) to synthesize U.S.-based studies utilizing dried blood spot (DBS) sampling to examine associations between psychosocial factors and systemic inflammation, as measured by C-reactive protein (CRP), and (2) to evaluate the methodological utility of DBS for advancing inclusive, population-based biomarker research.

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Background: Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, is used in the treatment of B-cell malignancies (e.g., chronic lymphocytic leukemia [CLL]).

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Dried blood spot sampling offers a scalable strategy to close diagnostic gaps and improve global surveillance for cardiovascular-kidney-metabolic syndrome. However, assay performance and the extent of validity vary widely between biomarkers used in cardiovascular-kidney-metabolic health assessment under different settings and have not been well described. To fill this gap, we conducted a systematic search of the literature and a narrative synthesis through April 2024 and included reports with laboratory or field validation measuring biomarkers that can be used in cardiovascular-kidney-metabolic health assessment.

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