Cost of Deconstruction Depots for Diversified, Waste-Based Lignocellulosic Sugars Using Distillable Solvents.

Transitioning to a bioeconomy that makes use of low-emission and waste feedstocks requires greater flexibility to accommodate seasonal variations and mitigate long-term storage challenges, such as material loss and fire risk. To achieve this goal, biomass deconstruction technologies must efficiently handle diverse feedstocks. Here, we assess the cost of using butylaminea distillable solventto deconstruct 22 different biomass feedstocks: 7 herbaceous, 9 woody, 4 food processing residues, and 2 blends.

The relationships between cerebrospinal fluid neurofilament light chain and hippocampal atrophy with cognitive decline.

BackgroundIdentifying predictive biomarkers of cognitive decline is critical for timely intervention in early Alzheimer's disease and related dementia. Biomarkers such as cerebrospinal fluid (CSF) neurofilament light (NfL), and MRI-based hippocampal atrophy are potential indicators of neurodegeneration, but their long-term predictive value remains unclear.ObjectiveThis study examined 20-year longitudinal associations between CSF NfL, MRI-based hippocampal atrophy, and cognitive decline in cognitively normal older adults.

Structural and social determinants of dementia risk among adults racialized as Black: Results from a community-based system dynamics approach.

Introduction: Alzheimer's disease and related dementias (ADRD) disproportionately affect Black Americans compared to non-Hispanic White individuals. We examined perceived dementia risk factors among Black adults in St. Louis via a participatory approach.

Longitudinal associations between speech-in-noise deficits and cognitive function over 8 years: the role of hearing aid use and environmental noise exposure.

Objective: Hearing loss is a potentially modifiable risk factor for dementia, yet questions remain about its impact on cognitive trajectories. Hearing aid use has been proposed as a protective intervention, but findings are mixed. This study examined longitudinal associations between hearing loss, hearing aid use, and cognitive function, and explored the role of environmental noise exposure.

The effect of anti-seizure medications on Alzheimer's disease (AD) risk and AD-related symptoms: A scoping review.

BackgroundAs the fastest-growing segment of the population, adults over 65 are at the most significant risk for Alzheimer's disease (AD). Older adults often use anti-seizure medications (ASMs), which can negatively impact cognitive function, mood, and behavior, mimicking AD or its symptoms. Understanding the effects of ASMs across diverse older adults is crucial, given that some ethnoracial groups are at higher risk for AD or more severe symptoms compared to non-Hispanic Whites.

Splenic Artery Embolization in Living Donor Liver Transplant Recipients: Indications, Safety and Clinical Outcomes.

Purpose: Splenic artery embolization (SAE) is a minimally invasive interventional radiology (IR) procedure that plays an important role in the management of complications in a certain subgroup of liver transplant recipients. SAE is technically of two types - proximal (P-SAE) and distal (D-SAE). There is limited data regarding the role of SAE in liver transplant recipients.

Dementia Risk and Social Determinants of Health Among Adults Racialized as Black: A Community-Based System Dynamics Perspective.

Background: The aging population in the USA is projected to increase significantly, with a corresponding rise in dementia cases, particularly among racial minorities. This study examines the key drivers of racial disparities in dementia risk among older Black adults in the St. Louis area, a region characterized by entrenched structural racism.

Aspirin Metabolites and Mammographic Breast Density in Premenopausal Women.

Background: Studies investigating the associations of self-reported aspirin use and mammographic breast density (MBD) have reported conflicting results. Therefore, we investigated the associations of aspirin metabolites with MBD in premenopausal women.

Methods: We performed this study on 705 premenopausal women who had a fasting blood draw for metabolomic profiling.

Hydrothermal pretreatment for valorization of genetically engineered bioenergy crop for lipid and cellulosic sugar recovery.

Lipids accumulated in the vegetative tissues of cellulosic feedstocks can be a potential raw material for biodiesel and bioethanol production. In this work, bagasse of genetically engineered sorghum was subjected to liquid hot-water pretreatment at 170, 180, and 190 °C for different reaction time. Under the optimal pretreatment condition (170 °C, 20 min), the residue was enriched in glucan (57.

Biodiesel from oil produced in vegetative tissues of biomass - A review.

Biodiesel is a green, renewable alternative to petroleum-derived diesel. However, using vegetable oil for biodiesel production significantly challenges the food security. Progress in metabolic engineering, understanding of lipid biosynthesis and storage have enabled engineering of vegetative tissues of plants such as sugarcane, sorghum, and tobacco for lipid production.

Low degree of polymerization xylooligosaccharides production from almond shell using immobilized nano-biocatalyst.

In this work, the effect of particle size on alkali pretreatment of the almond shell was evaluated for recovery of hemicellulose. Further, endoxylanase from Thermomyces lanuginosus was immobilized on Fe-based magnetic nanoparticles to enable reuse of enzyme. Reduction in particle size significantly influences the recovery of hemicellulose as particle size below 120 μm enable recovery of 97% available hemicellulose in 1 h at 121 °C with 2 M alkali.

Production and faecal fermentation of pentose oligomers of hemicellulose: Study of variables influencing bioprocess efficiency.

Almond shell, a by-product obtained from the nut industry, was valorised into low degree of polymerisation xylooligosaccharides using alkaline pretreatment and enzymatic hydrolysis. The effect of particle size on hemicellulose recovery upon pretreatment was studied using 1 and 2 M NaOH. It was observed that particle size significantly influences hemicellulose recovery, as particles below 120 µm resulted in near complete recovery at 2 M NaOH.

Bioactives from fruit processing wastes: Green approaches to valuable chemicals.

Fruit processing industries contribute more than 0.5billion tonnes of waste worldwide. The global availability of this feedstock and its untapped potential has encouraged researchers to perform detailed studies on value-addition potential of fruit processing waste (FPW).