Effect of a brief, focal acceptance and commitment therapy (ACT) protocol to accelerate repetitive transcranial magnetic stimulation treatment with theta-burst stimulation (TBS) for elderly patients with depression: A randomized, blinded, controlled clinical trial.

Background: Major depressive disorder (MDD) is one of the leading causes of disability, especially among elderly. Repetitive transcranial magnetic stimulation (rTMS) is an effective non-pharmacological treatment and theta burst stimulation (TBS) technique offers shorter sessions. Acceptance and Commitment Therapy (ACT) is a proven effective intervention in the treatment of MDD.

Treatment of depression in the elderly with repetitive transcranial magnetic stimulation using theta-burst stimulation: Study protocol for a randomized, double-blind, controlled trial.

Introduction: Transcranial magnetic stimulation (TMS) is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation (TBS) is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group.