Free energy of a two-liquid system of charge carriers in strongly coupled electron and phonon fields and common nature of three phases in hole-doped cuprates.

Hole-doped cuprates exhibit partially coexisting pseudogap (PG), charge ordering (CO) and superconductivity; we show that there exists a class of systems in which they have a single nature as it has recently been supposed. Since the charge-ordered phase exhibits large frozen deformation of the lattice, we develop a method for calculating the phase diagram of a system with strong long-range (Fröhlich) electron-phonon interaction. Using a variational approach, we calculate the free energy of a two-liquid system of carriers with cuprate-like dispersion comprising a liquid of autolocalized carriers (large polarons and bipolarons) and Fermi liquid of delocalized carriers.

Increased Yield of Residual γH2AX Foci in p53-Deficient Human Lung Carcinoma Cells Exposed to Subpicosecond Beams of Accelerated Electrons.

We studied quantitative yield of residual (24 h post-irradiation) phosphorylated histone (γH2AX) foci as a marker of DNA double strand breaks in wild-type A549 and p53-deficient H1299 human lung carcinoma cells after exposure to subpicosecond (energy 4 MeV, pulse duration 400 fsec, peak dose rate during the pulse 16 GGy/s) and quasi-continuous (energy 3.6 MeV) beams of accelerated electrons in a dose range of 0.5-10.

[PROPERTIES OF INDIVIDUAL CONTRACTILE RESPONSES WITHIN TETANUS OF RAT SLOW MUSCLE UNDER CONDITIONS OF MODULATION OF SARCOPLASMIC RETICULUM Ca²⁺ RELEASE].

During direct stimulation of m. Soleus by trains of 5, 10 and 50 stimuli with a frequency of 20 Hz in control experiments (n = 16) a biphasic change was observed in the amplitude of the last contractile responses (LCRN) depending on N, where N is the number of individual contractile responses within the te- tanus. Thus, an initial decrease of LCRN amplitude (up to 54 ± 8 % for LCR₅) was replaced by their subsequent growth (up 218 ± 14 % for LCR5o) associated with a significant shortening of their half-relaxation time relative to the initial response (to 44 ± 8 % for LCR₅₀).

[TRANSFORMATION OF INDIVIDUAL CONTRACTILE RESPONSES DURING TETANUS IN FAST AND SLOW RAT SKELETAL MUSCLES].

The last contractile responses (LCRN), where N is the number of individual contractile responses within tetanus, were separated from the integral tetanic responses of fast, m. Extensor digitorum longus (m. EDL), and slow, m.

[Effect of insulin on characteristics of contractile responses of fast and slow skeletal muscles of rats with streptozotocin-induced overt diabetes].

Comparison of amplitude-time characteristics of fast (m. EDL) muscles in rats with acute model of streptozotocin diabetes (SD) (12 and 30 days after treatment with streptozotocin) did not reveal significant changes in strength of single normalized contractile responses as compared with control. In slow (m.