Validation of salivary microRNA 301a as a potential non-invasive diagnostic biomarker in gastric carcinoma.

Context: Early detection of cancer is key to good prognosis and improved survival rate. Gastric cancer (GC) is fatal and presents with poor prognosis as it is usually diagnosed only at advanced stages. Saliva is emerging as a preferred diagnostic tool due to its advantages of being non-invasive, easy to collect, and cost-effective.

Comparison of stress related physiological parameters with biological parameters of saliva among college students - An observational study.

Background: Stress can also be defined as a physical, mental, or emotional response to events that causes bodily or mental tension. Starting with a lack of concentration, it creates a lot of inconveniences and problems with a snowball effect. Saliva, a prime component of the oral cavity, plays an important role in oral health.

Bedside repair of scrotoschisis with local anaesthesia for a neonate with bilateral testicular evisceration.

Scrotoschisis is a congenital opening in the scrotal wall that allows extrusion of one or both testicles. We describe a newborn male who was found to have exteriorisation of both testes through a 2 cm midline defect in the anterior wall of the scrotum. Both testes were stained with meconium.

Preclinical Medical Students' Perspectives and Experiences With Structured Web-Based English for Medical Purposes Courses: Cross-Sectional Study.

Background: English for medical purposes (EMP) is essential for medical students as it serves as a foundational language for medical communication and education. However, students often undervalue its importance within the medical curriculum. Given their demanding schedules and workload, educational methods for EMP must align with their needs.

Fetal context conveys heritable protection against MLL-rearranged leukemia that depends on MLL3.

rearrangements ( r) are the most common cause of congenital and infant leukemias. r arise prior to birth and require few cooperating mutations for transformation, yet congenital leukemias are 10-fold less common than infant leukemias and >100-fold less common than childhood leukemias overall. This raises the question of whether mechanisms exist to suppress leukemic transformation during fetal life, thereby protecting the developing fetus from malignancy during a period of rapid hematopoietic progenitor expansion.