Publications by authors named "Quitterie Murat de Montai"
Background: Cutaneous lupus erythematosus (CLE) is associated with unpredictable flares and may induce permanent damage. There is currently no biomarker routinely available in CLE.
Objective: To evaluate the performance of interferon-α (IFN-α) biological activity as biomarker of CLE activity and risk of flare.
Article Synopsis
- Cutaneous lupus erythematosus (CLE) can occur on its own or alongside systemic lupus erythematosus (SLE), where lab tests show specific abnormalities.
- This study aimed to compare isolated CLE to CLE with lab-confirmed SLE and to validate a scoring system predicting the risk of developing severe SLE (sSLE).
- Results indicated that patients with CLE and laboratory SLE had a significantly higher risk of progressing to sSLE compared to those with isolated CLE, though the study had limitations due to its small, single-center patient sample.