Characteristics and Pathologic Results of Foci on Breast Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis.

Background: Although T2-weighted imaging (T2WI) hypointensity, delayed enhancement washout pattern, interval growth, and new appearance of a focus have been associated with malignancy, the results are not consistent.

Purpose: To investigate the malignancy rate and identify the clinical and imaging characteristics associated with malignancy among foci in breast MRI.

Study Type: Meta-analysis.

Innovations in the localization techniques for non-palpable breast lesions: Make invisible visible.

Non-palpable breast cancer lesions pose a challenge for surgeons to resect cancer lesions. Making 'invisible' lesions 'visible' is the main strategy. Currently, multiple preoperative localization techniques have been applied in clinical.

An on-Demand Oxygen Nano-vehicle Sensitizing Protein and Nucleic Acid Drug Augment Immunotherapy.

Hypoxia severely limits the antitumor immunotherapy for breast cancer. Although efforts to alleviate tumor hypoxia and drug delivery using diverse nanostructures achieve promising results, the creation of a versatile controllable oxygen-releasing nano-platform for co-delivery with immunostimulatory molecules remains a persistent challenge. To address this problem, a versatile oxygen controllable releasing vehicle PFOB@F127@PDA (PFPNPs) is developed, which effectively co-delivered either protein drug lactate oxidase (LOX) or nucleic acids drug unmethylated cytosine-phosphate-guanine oligonucleotide (CpG ODNs).