Commercially Available Blue Diode Laser Engraver Operating at 455 nm as an Affordable LD-REIMS Ionization Source.

Lasers are commonly used for mass spectrometric applications to perform laser ablation-desorption and ionization; however, the use of visible light is not very common. Here, we report a commercially available visible light laser engraver operating at 455 nm as an ionization source, generating rich spectral profiles featuring predominantly lipid species, such as fatty acids and glycerophospholipids. Laser settings such as the speed of movement over the sample and laser power were tested, resulting in an optimum laser speed of 300 mm/min and a laser power of 30-50% for the analysis of fresh salmon tissue samples.

Efficient Purification of Cowpea Chlorotic Mottle Virus by a Novel Peptide Aptamer.

The cowpea chlorotic mottle virus (CCMV) is a plant virus explored as a nanotechnological platform. The robust self-assembly mechanism of its capsid protein allows for drug encapsulation and targeted delivery. Additionally, the capsid nanoparticle can be used as a programmable platform to display different molecular moieties.