Publications by authors named "Prakash Choudhary"

Disease classification in maize plant is necessary for immediate treatment to enhance agricultural production and assure global food sustainability. Recent advancements in deep learning, specifically convolutional neural networks, have shown outstanding potential for image classification. This study presents Maize Net, a convolutional neural network model that precisely identifies diseases in maize leaves.

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With the technological revolution, the Internet of medical things (IoMT) has developed to be of immense benefit. In IoMT, medical images and patients' data are widely transmitted through private/public network. An ideal transmission should not jeopardize the security, confidentiality, authenticity, authorization, or integrity of medical data/images.

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Congestive heart failure (CHF) is one of the primary sources of mortality and morbidity among the global population. Over 26 million individuals globally are affected by heart disease, and its prevalence is rising by 2% yearly. With advances in healthcare technologies, if we predict CHF in the early stages, one of the leading global mortality factors can be reduced.

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Article Synopsis
  • The study aims to enhance cardiac anomaly detection using specific Daubechis wavelet families to differentiate between normal and abnormal ECG signals, especially in the context of sleep apnea analysis.
  • By applying machine learning techniques like Principal Component Analysis and various classifiers, the research seeks to improve the accuracy of identifying cardiac irregularities through longer ECG signal events.
  • Key results show that the db5 wavelet family outperforms others in correctly categorizing ECG signals, achieving 100% accuracy for healthy signals and 97.8% for problematic ones, highlighting the effectiveness of the methods used.
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The coronavirus disease 2019, initially named 2019-nCOV (COVID-19) has been declared a global pandemic by the World Health Organization in March 2020. Because of the growing number of COVID patients, the world's health infrastructure has collapsed, and computer-aided diagnosis has become a necessity. Most of the models proposed for the COVID-19 detection in chest X-rays do image-level analysis.

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The setback in the practical clinical use of RNA interference (RNAi)-based cancer treatment stems from the lack of targeted small interfering RNA (siRNA) delivery. Here, we show that luteinizing hormone-releasing hormone(LHRH) analog-tethered multi-layered polyamidoamine (PAMAM) nanoconstructs silence the anti-apoptotic MCL-1 gene in LHRH receptor overexpressing human breast (MCF-7) and prostate cancer (LNCaP) cells with 70.91 % and 74.

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COVID-19 is an infectious disease that has cost millions of lives all over the world. A faster and safer diagnosis of COVID-19 is highly desirable in order to stop its spread. An electrocardiogram (ECG) signal-based diagnosis has shown its potential in the diagnosis of cardiac, stroke, and COVID-19.

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Chest radiography (X-ray) is the most common diagnostic method for pulmonary disorders. A trained radiologist is required for interpreting the radiographs. But sometimes, even experienced radiologists can misinterpret the findings.

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COVID-19 is an acronym for coronavirus disease 2019. Initially, it was called 2019-nCoV, and later International Committee on Taxonomy of Viruses (ICTV) termed it SARS-CoV-2. On 30th January 2020, the World Health Organization (WHO) declared it a pandemic.

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Study Question: Is the DNA damage response (DDR) dysregulated in the eutopic endometrium of women with endometriosis?

Summary Answer: Endometrial expression of genes involved in DDR is modulated in women with endometriosis, compared to those without the disease.

What Is Known Already: Ectopic endometriotic lesions are reported to harbour somatic mutations, thereby hinting at dysregulation of DDR and DNA repair pathways. However, it remains inconclusive whether the eutopic endometrium also manifests dysregulated DDR in endometriosis.

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A 22-year-old male presented with 6 days history of intermittent fever with chills, 2 days history of upper abdomen pain, distension of abdomen, and decreased urine output. He was diagnosed to have Plasmodium vivax malaria, acute pancreatitis, ascites, and acute renal failure. These constellations of complications in P.

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Malaria is the most important parasitic diseases of humans and one of the leading causes of morbidity and mortality in tropical countries. Earlier Plasmodium vivax was considered as a benign infection, but now it is recognized as a cause of severe malarial disease. It causes severe malarial disease similar to those as Plasmodium falciparum including cerebral malaria, severe anaemia, severe thrombocytopenia, hepatic dysfunction, shock, acute respiratory distress syndrome (ARDS), acute renal failure, and pulmonary oedema.

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Small fiber neuropathy typically involves the small diameter nerve fibers, is usually idiopathic, and presents with peripheral pain. It can be excruciatingly painful at times despite the best of treatments. We present the case of a 22-year-old postoperative case of right frontoparietal oligodendroglioma who received multiple drugs for his severe neuropathic pain without significant relief.

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Chemotherapy-induced peripheral neuropathy (CIPN) is a frequently encountered complication. It can result from a host of agents. Various modalities of treatment have been advocated, of which a novel method is radio frequency ablation.

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Purpose: To compare the prevalence of different types and densities of age-related cataract in subjects with high myopia and emmetropia in an Indian urban clinic-based population.

Design: Prospective, observational, clinic-based case-control study.

Methods: An observational case-control study of 800 healthy eyes was undertaken at Iladevi Cataract & IOL Research Center, Ahmedabad, India.

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