Potential role of immune-related LncRNAs in prognosis of hepatocellular carcinoma: an integrative study.

Background: Hepatocellular carcinoma (HCC) represents a significant global health concern with persistently high incidence and mortality rates. Immune-related long non-coding RNAs (lncRNAs) may play crucial roles in the pathogenesis and progression of HCC, yet their precise mechanisms remain incompletely elucidated.

Objective: This study aims to explore the potential roles of immune-related lncRNAs in HCC patients through systematic biological approaches, integrating clinical data with bioinformatics analysis, and to construct a COX regression model for predicting patient survival.

An association study of m6A methylation with major depressive disorder.

Objective: To find the relationship between N6-methyladenosine (m6A) genes and Major Depressive Disorder (MDD).

Methods: Differential expression of m6A associated genes between normal and MDD samples was initially identified. Subsequent analysis was conducted on the functions of these genes and the pathways they may affect.

Celestial Insights: Unraveling the Role of miR-3682-3p in Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) remains a formidable oncological challenge, calling for innovative therapeutic strategies to improve patient outcomes. MicroRNAs have emerged as key regulators in cancer, and miR-3682-3p shows potential as a diagnostic and prognostic biomarker in HCC. We conducted a comprehensive study to uncover its role in HCC biology, revealing dysregulation and clinical associations.

An association study of clock genes with major depressive disorder.

Objective: To study the relationship between clock genes and Major Depressive Disorder (MDD).

Methods: GEO database was used to obtain the chip data and clinical information of datasets GSE98793, GSE39653 and GSE52790. The differentially expressed clock genes were found through the analysis of the differentially expressed genes between MDD and healthy controls.