Publications by authors named "Paula Ramirez-Palacios"

Introduction: Violence is a major public health problem, which increased during the Covid-19 pandemic, affecting the physical and mental development of adolescents.

Objective: To analyze factors associated with interpersonal violence and depressive symptoms in adolescent students in the South of Jalisco.

Methods: Data were drawn from an online survey of 3,046 adolescents (12-19 years) conducted between September and December 2021.

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Objective: To assess associations between experienced violence and the use of combustible cigarettes, e-cigarettes, and of both products ("dual use") among adolescent students from Mexico.

Methods: Data comes from an online survey among 3,046 adolescents (12-19 years) conducted between September and December 2021. Students reported experiences of neglect, physical, psychological, and sexual violence perpetrated by household members, and digital violence (by anyone) in the previous 12 months, as well as current (last 30 day) use of cigarettes and e-cigarette.

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Objetivo: Identificar diferencias en las barreras de acceso a los servicios de salud entre población con y sin condiciones de vulnerabilidad a partir de resultados de la Encuesta Nacional de Salud y Nutrición Continua 2023 (Ensanut Continua 2023). Material y métodos. Se definieron cuatro categorías de vulnerabilidad entre la población con necesidades de salud que no buscó atención y utilizadores de los servicios de salud que acudieron a instituciones que no les correspondía.

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Background: No study has assessed the impact of flavor capsule cigarettes (FCCs) on smoking cessation. Thus, the purpose of this exploratory study was to assess (1) the sociodemographic and smoking-related characteristics associated with using FCCs, and (2) the preliminary impact of FCCs on smoking cessation.

Methods: This study is a secondary data analysis of a single-arm study with 100 individuals living in Mexico who smoked and received a smoking cessation mHealth intervention and pharmacotherapy support.

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Background: Hypertension and type 2 diabetes (T2D) are the most prevalent noncommunicable diseases in Mexico and worldwide. According to international practice management guidelines, the principal chronic management therapy is daily oral medication.

Aim: We aim to describe the trends of antihypertensive, antidiabetic, and nonsteroidal anti-inflammatory (NSAID) drugs use among the Mexican adult population from 2004-2018.

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Objective: This study aimed to explore whether African American/Black and Hispanic/Latino adolescents are being asked about electronic cigarette (e-cigarette) use (vaping) and advised not to use them.

Methods: In 2021, adolescents ( = 362) with no vaping history, self-identified as African American/Black and/or Hispanic/Latino, and able to read and speak English and/or Spanish were recruited through partner schools and community-based organizations. Participants completed a survey reporting sociodemographic characteristics (e.

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Background: COVID-19 health emergency caused an increase in the demand for hospitalization and high costs for the health system.

Objective: To estimate COVID-19 care direct costs from the perspective of the healthcare provider in a secondary care hospital that underwent conversion during the first year of health emergency.

Material And Methods: Retrospective, observational study.

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The objective of this study was to evaluate the effectiveness of digital and traditional methods and strategies in the recruitment of Mexican individuals who smoke into a cessation study. Recruitment method refers in general to either digital or traditional recruitment. Recruitment strategies refer to the particular recruitment type utilized within each recruitment method.

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We developed a Sustainable Dietary Score (SDS) based on the EAT-Lancet commission's recommendations and evaluated its adherence in a sample of Mexican adults. We used data on 1908 men and women aged 19 to 59 participating in the Health Workers Cohort Study in 2004. Fourteen of the healthy reference diet components were used to develop the SDS.

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Background: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, and diabetes. The aim of this study was to better understand differences in the lipid composition of individuals with NAFLD compared to controls, by performing direct infusion lipidomics on serum biospecimens from a cohort study of adults in Mexico.

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Unlabelled: We evaluated the association between leisure-time physical activity (LTPA), bone mineral content (BMC), and lean mass (LM) in whole body (wb) and limbs of the Mexican adult population. Our results demonstrate that some types of LTPA with relatively high/medium impact on bones such as football, basketball, tennis, and weightlifting improve BMC and LM.

Purpose: To evaluate the effect of different kinds of leisure-time physical activity (LTPA) on bone mass values and its association with lean mass (LM) in the whole body (wb) and limbs of a large sample of Mexican men and premenopausal (pre-MP) women.

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Background: The goal of this study was to determine whether the detection of histologically confirmed cases of cervical high-grade squamous intraepithelial lesions or worse (HSIL+) can be increased by having each liquid-based cytology (LBC) slide read by 2 cytotechnologists as part of routine screening.

Methods: Over 36,212 women aged 30 to 64 years participated in the Forwarding Research for Improved Detection and Access for Cervical Cancer Screening and Triage (FRIDA) Study in Mexico between 2013 and 2016. For each participant, 2 cervical samples were collected at the same clinic visit, one to test for high-risk human papillomavirus (hrHPV) and the other for LBC, which was used to triage those with a hrHPV positive result.

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Background: While soft drink intake is positively associated with weight gain, no previous study has investigated whether leisure-time physical activity modifies this association. We estimated the association between soft drink intake and body weight, and explored if this association differed by levels of leisure-time physical activity.

Methods: We used data from the health workers cohort study, a prospective study of Mexican adults (20 to 85y old), including 1268 health workers and their families, who were assessed at baseline (2004-2006) and follow-up (2010-2012).

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Objective: To examine changes in categories of soft drink consumption in a cohort of Mexican adults, three years after the implementation of the sugar sweetened beverage tax.

Design: Open cohort longitudinal analysis.

Setting: Three waves of the Health Workers Cohort Study, Mexico, spanning 2004 to 2018.

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Objective: Our aim was to examine prospectively predictors of subclinical renal alterations among adults without chronic kidney disease.

Materials And Methods: We analyzed data from a cohort of Mexican adults (n=757). Kidney function (2010) was assessed with the estimated glomerular filtration rate (eGFR-Cr), serum creatinine and uric acid.

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Aim: To determine the association between known risk factors (e.g., obesity, metabolic syndrome and its components) and the development of pre-diabetes or diabetes over time in a cohort of Mexican health workers.

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Osteoporosis is a skeletal disease mainly affecting women over 50 years old and it represents a serious public health problem because of the high socioeconomic burden. This disease is characterized by deterioration of bone microarchitecture, low bone mineral density (BMD), and increased risk of fragility fractures. This study aimed to identify serum useful proteins as biomarkers for the diagnosis and/or prognosis of osteoporosis and fracture risk.

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Background: Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance of S5 (targeting DNA methylation in HPV16, HPV18, HPV31, HPV33, and human gene EPB41L3) to predict cervical intraepithelial neoplasia grade 2 or higher (CIN2+) in a sample of hrHPV-infected women referred to colposcopy in the FRIDA Study, a large screening trial in Mexico. A nested case-control sample with women referred to colposcopy either by atypical squamous cells of undetermined significance or higher (ASCUS+) in cytology and/or positive for HPV types 16 or 18 was tested by S5.

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Article Synopsis
  • Hyperuricemia risk is influenced by both genetic and environmental factors, and this study focuses on identifying those factors in a Mexican population.
  • A pilot genome-wide association study (GWAS) analyzed data from 411 participants, leading to the identification of four significant SNPs linked to serum uric acid levels, which were confirmed in larger groups.
  • Non-genetic factors such as visceral fat, smoking, and metabolic syndrome components were associated with higher uric acid levels, with increased soft drink consumption raising hyperuricemia odds in women, highlighting the roles of diet and genetics in the condition's prevalence in Mexico.
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The aim of this study was to examine various psychosocial, behavioral, and socio-environmental factors in a multiethnic sample of healthy-weight, overweight, and obese youths in the United States (US) and Mexico and determine differences by sex. We conducted a cross-sectional analysis of 633 youths aged 11-18 years who completed a self-reported questionnaire. Height and weight were measured to determine body mass index (BMI).

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Objective: To estimate the burden of genital warts (GW)in Mexico.

Materials And Methods: We estimated the annual incidence of GW based on data reported by specialist physicians. We also assessed GW treatment practices, the average cost of treatment, and the psychosocial burden of GW among patients.

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Aim: To compare the prevalence of chronic liver disease (CLD) risk factors in a representative sample of Mexican-Americans born in the United States (US) or Mexico, to a sample of adults in Mexico.

Methods: Data for Mexican-Americans in the US were obtained from the 1999-2014 National Health and Nutrition Examination Survey (NHANES), which includes persons of Mexican origin living in the US ( = 4274). The NHANES sample was restricted to Mexican-American participants who were 20 years and older, born in the US or Mexico, not pregnant or breastfeeding, and with medical insurance.

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Osteoporosis is a metabolic bone disorder characterized by low bone mineral density and decreased bone strength, leading to an increased risk of fractures with a consequent increase in morbidity and mortality. The current methods to estimate the fracture risk are very limited. microRNAs (miRNAs) have been considered as good biomarkers for many pathological processes, including osteoporosis.

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Background: In Mexico, 40% of hypertensive patients see their blood pressure under control. The evidence to keep hypertension (HT) under control is scarce, particularly in older adults who have the highest prevalence and require more health services. The objective was to determine the impact of a double intervention to increase the percentage of hypertensive patients with blood pressure levels under control and estimate differences among adults and older adults.

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Non-alcoholic fatty liver disease (NAFLD) is the accumulation of extra fat in liver cells not caused by alcohol. Elevated transaminase levels are common indicators of liver disease, including NAFLD. Previously, we demonstrated that PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), and GCKR (rs780094) are associated with elevated transaminase levels in overweight/obese Mexican adults.

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