Computed tomography shows limited accuracy in differentiating histological types of canine ear canal masses.

Objective: To describe the epidemiological characteristics and CT features in dogs with external ear canal (EEC) masses and assess the ability of CT to predict histopathological diagnosis.

Methods: This was a retrospective, single-center study including 70 dogs that underwent otoendoscopic examination, head CT imaging, and histopathological analysis. Masses were categorized into 5 groups according to histopathological diagnosis.

Prevalence of immunoglobulin E sensitisation to mites and pollens in 25,451 French dogs from 2016 to 2022.

Background: Canine atopic dermatitis (cAD) is a common skin disorder in dogs, wherein allergens are presumed to exert a significant influence. The prevalence of allergen sensitisation in dogs with suspected cAD remains inadequately investigated in France.

Hypothesis/objectives: This study aimed to analyse allergen-specific immunoglobulin (Ig)E test results from French dogs with suspected cAD, exploring potential risk factors influencing sensitisation.

Ciclosporin oral solution in cats: a retrospective survey of compliance with treatment and adverse effects.

Objectives: The aim of the study was to assess long-term ciclosporin oral solution compliance in cats treated for feline atopic skin syndrome (FASS).

Methods: A survey was sent by email to 114 owners who had administered ciclosporin oral solution to their cats for FASS.

Results: In total, 42 owners completed the survey.

Alopecia X in a cloned Pomeranian dog.

A two-year-old Pomeranian dog with Alopecia X was cloned after accidental death. Despite earlier castration, the cloned animal developed the same lesions of Alopecia X at the same age. This observation suggests that the disease is due to genetically programmed hair cycle arrest without strong environmental influences.

Open field study on the efficacy of fluralaner topical solution for long-term control of flea bite allergy dermatitis in client owned cats in Ile-de-France region.

Background: Flea bite is considered to be the main cause of allergic dermatitis in cats. There is a need for treatments able to control clinical signs of allergic dermatitis associated with flea bite in cats. This was an open pre-treatment versus post-treatment clinical field study.

The novel high molecular weight Dermatophagoides farinae protein Zen-1 is a major allergen in North American and European mite allergic dogs with atopic dermatitis.

Background: Atopic dogs with hypersensitivity to Dermatophagoides farinae (Df) have IgE recognizing high molecular weight (MW) allergens more often than the low MW Der f 1 and 2. A new high MW Df allergen, Zen-1, has been identified recently.

Objectives: To determine the IgE reactivity of American and European Df-hypersensitive dogs to Zen-1, Der f 1 and Der f 2.

Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats.

Background: To diagnose cutaneous adverse food reactions (CAFRs) in dogs and cats, dietary restriction-provocation trials are performed. Knowing the most common offending food allergens for these species would help determining the order of food challenges to optimize the time to diagnosis.

Results: The search for, and review and analysis of the best evidence available as of January 16, 2015 suggests that the most likely food allergens contributing to canine CAFRs are beef, dairy products, chicken, and wheat.

Critically appraised topic on adverse food reactions of companion animals (1): duration of elimination diets.

Background: Restrictive (i.e. elimination)-provocation dietary trials remain the standard of care to diagnose cutaneous adverse food reactions (CAFRs) in dogs and cats.

Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA).

Background: In 2010, the International Task Force on Canine Atopic Dermatitis (now International Committee on Allergic Diseases of Animals, ICADA) published the first consensus guidelines for the treatment of atopic dermatitis (AD) in dogs. This is the first 5-year minor update of this document.

Results: The treatment of acute flares of AD should involve the search for, and then elimination of, the cause of the flares, bathing with mild shampoos, and controlling pruritus and skin lesions with interventions that include topical and/or oral glucocorticoids or oclacitinib.

Dose tapering for ciclosporin in cats with nonflea-induced hypersensitivity dermatitis.

Background: Little information is available on the ciclosporin dose-tapering regimen and clinical response in the treatment of feline hypersensitivity dermatitis.

Hypothesis/objectives: To test a dose-tapering regimen and assess efficacy and clinical safety for up to 18 weeks.

Animals: Eighty-eight client-owned cats with feline hypersensitivity dermatitis.

Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis.

Atopic dermatitis (AD) is a common chronic relapsing pruritic skin disease of dogs for which treatment has varied over time and geographical location. Recent high quality randomized controlled trials and systematic reviews have established which drugs are likely to offer consistent benefit. The International Task Force for Canine AD currently recommends a multi-faceted approach to treat dogs with AD.

Determination of CADESI-03 thresholds for increasing severity levels of canine atopic dermatitis.

To evaluate the extent and severity of skin lesions in clinical trials enrolling dogs with atopic dermatitis (AD), the International Task Force on Canine Atopic Dermatitis recently recommended the use of the third version of the CADESI. This version of the CADESI was found to exhibit acceptable content, construct, criterion, inter- and intraobserver reliability and sensitivity to change. The current study was aimed at determining optimal CADESI-03 cut-off points to separate AD severity categories for future clinical trials.

Cutaneous manifestations of neurological diseases: review of neuro-pathophysiology and diseases causing pruritus.

Pruritus does not always originate from stimulation to the skin associated with primary dermatological disorders. It may be caused by neurological or behavioural disorders. The essential role of the nervous system in the control (enhancement and inhibition) of pruritus and its pathophysiology are presented.

Randomized controlled trial of the efficacy of cyclosporine in the treatment of atopic dermatitis in dogs.

Objective: To evaluate efficacy of cyclosporine A, administered at either of 2 dosages, in dogs with atopic dermatitis (AD).

Design: Multicenter randomized controlled trial.

Animals: 91 dogs with AD.

Sensitisation to the House Dust Mite, Dermatophagoides farinae, in Dogs with Sarcoptic Mange.

Abstract- Sensitisation to the house dust mite, Dermatophagoides farinae, was demonstrated by skin testing and allergen-specific IgG determination in 15 out of 20 dogs in which a definitive diagnosis of sarcoptic mange was made following recovery of Sarcoptes scabiei mites on skin scrapings. After therapy, no dogs exhibited clinical signs of atopic dermatitis. Intradermal skin testing and 40 per cent of specific IgG assays for Dermatophagoides farinae were negative 90-180 DAys after the original diagnosis.