Publications by authors named "Stephane Madec"

Article Synopsis
  • Tympanokeratomas (cholesteatomas) are harmful growths in the middle ear and are often surgically treated; this study focuses on using non-EP diffusion-weighted MRI for diagnosis in dogs.
  • The research involved analyzing 62 dog ears diagnosed with either tympanokeratomas or other types of otitis media, with non-EP DWI achieving a detection accuracy of 77.4% and ADC values ranging between 517 to 2447 mm/s.
  • A specific ADC cut-off value of 916 mm/s was found to effectively indicate tympanokeratomas, providing a combined 80.9% accuracy when considering both qualitative DWI images and ADC maps.
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Magnetic resonance imaging is the gold standard for diagnosing intervertebral disc (IVD) degeneration in dogs. However, published methods for quantifying severity or progression of IVD degeneration are currently limited. Mapping MRI sequences are used in humans for quantifying IVD degeneration but have rarely been applied in dogs.

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Regenerative medicine is considered an attractive prospect for the treatment of intervertebral disc (IVD) degeneration. To assess the efficacy of the regenerative approach, animal models of IVD degeneration are needed. Among these animal models, chemonucleolysis based on the enzymatic degradation of the Nucleus Pulposus (NP) is often used, but this technique remains far from the natural physiopathological process of IVD degeneration.

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The purpose of this work is to examine the gross visceral anatomy of ocean sunfish and angler using non-invasive imaging techniques: computed tomography imaging (CT) and magnetic resonance imaging (MRI). Similarities and differences in the internal organisation of these two species are verified. Both species lack a swimbladder and present a significant asymmetry in the hepatic lobes, an elongated bile duct terminating close to the stomach, a compact thyroid embedded in a blood lacuna, and very reduced brain and spinal cord.

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Objective: To investigate renal function in clinically normal dogs when awake and during anesthesia with medetomidine; xylazine, ketamine, and halothane (XKH) combination; or propofol.

Animals: 10 adult female Beagles.

Procedures: At intervals of 15 days, dogs were administered medetomidine (0.

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