Publications by authors named "Pascal Megier"

Article Synopsis
  • This clinical trial aimed to determine if daily low-dose aspirin could lower the risks of preeclampsia and fetal growth restriction in first-time pregnant women identified as high risk through early ultrasound screenings.
  • Conducted in France, the study involved over 1,100 participants who were randomly assigned to either take low-dose aspirin or a placebo from early pregnancy until the 34th week.
  • Results showed no significant difference in the rates of preeclampsia or low birth weight between the aspirin and placebo groups, leading to the conclusion that low-dose aspirin does not provide benefits for these outcomes in the targeted population.
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To evaluate the migration of low-placental implantation (LPI) during the third trimester of pregnancy and its effect on delivery and post-partum hemorrhage. We conducted a retrospective study at a level 3 maternity center including all cases of placenta previa (PP) and LPI between 1998 and 2014. The distance (d) between cervical internal os (CIO) and placental edge (PE) were measured by vaginal ultrasonography in the third trimester of pregnancy at 32 and 3 weeks after.

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Article Synopsis
  • This study evaluates the effectiveness and safety of multiple square sutures in treating severe postpartum hemorrhage among women who delivered in a tertiary maternity center.
  • Out of 30 suture cases, 93% successfully stopped the hemorrhage, with a follow-up hysteroscopy showing mostly normal conditions or easily removable minimal adhesions in the uterus after 3 months.
  • The study concludes that while multiple square sutures are generally effective for controlling severe postpartum bleeding, some patients did develop adhesions, indicating a need for further research to compare different suture techniques.
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