Publications by authors named "Pascal Girardin"

Article Synopsis
  • - The study investigated immediate hypersensitivity reactions (IH) to iodinated and gadolinium-based contrast media (ICM; GBCM), focusing on differentiating between allergic and non-allergic responses, which is crucial for future medical treatment decisions.
  • - Over 245 patients were analyzed through skin tests and other clinical evaluations, revealing an allergic reaction rate of 19.6% for ICM and 27.8% for GBCM, with notable cross-reactivity among patients.
  • - The findings indicated that allergic IH was linked to more severe reactions and quicker onset than non-allergic IH, highlighting the need for more sensitive skin testing methods to better identify allergic responses to contrast agents.
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Article Synopsis
  • The study focuses on eyelid allergic contact dermatitis (EACD) in French patients, aiming to evaluate the effectiveness of a specific eyelid patch testing series.
  • Researchers analyzed data from 264 patients over two years, identifying positive test reactions in 167 participants, with 84 having currently relevant allergies mainly linked to cosmetics.
  • Key allergens identified included methylisothiazolinone and fragrance mix I, and patients with current atopic dermatitis showed a shorter duration of symptoms compared to others.
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Background: Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard.

Objectives: To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium.

Methods: A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)- and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint.

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Background: Currently used antimalarial drugs (AM) are hydroxychloroquine and chloroquine, which are prescribed for many autoimmune disorders. The value of skin tests on cutaneous adverse drug reactions (CADR) with AM remains unknown.

Objective: The main objective of this retrospective study is to know whether skin tests for AM are useful and how to manage the recovery of AM therapy in these patients.

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This study has two purposes:--to know whether the European standard series is still the key reference when it comes to contact dermatitis, i.e., are its components still the most frequently involved allergens in contact dermatitis nowadays?--to assess the results of the European standard series among French and Belgian dermatologists/allergists as, so far, most of them have failed to provide statistical data within the European community of allergists/dermatologists.

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