Background: The association of sugar sweetened beverages (SSBs) and coronary artery disease (CAD) has not been well-established in Asians, where SSBs are the leading ultra-processed food product.
Objective: We aim to examine the association between SSBs and premature CAD (PCAD) in Iranian adults.
Design: Case-control.
Background: Evidence on the combined impact of healthy lifestyle factors on cardiovascular disease (CVD) risk in the Iranian population is limited. This study aimed to examine the association between a healthy lifestyle score (HLS) and the incidence of CVD.
Methods: This prospective cohort study, including 5419 adults aged over 35 years, was performed in the framework of the Isfahan Cohort Study (ICS) which is an ongoing study.
Background: The association between plant and animal protein and the risk of cardiovascular disease has been established. However, the association between the plant-to-animal protein ratio and the risk of premature coronary artery disease (PCAD) remains unknown.
Objective: To explore the association between the plant-to-animal protein ratio and the risk of PCAD and severity of PCAD.
Background: Atherogenic indices outperform traditional lipid markers; however, the combined association of lifestyle habits with these indices remains unclear. This study, which is based on population data, explored the link between the Healthy Lifestyle Score (HLS) and various atherogenic indices.
Methods: In this cross-sectional analysis of the 2013 Isfahan Cohort Study 2 (participants aged ≥ 35 years), HLS was derived from four factors: smoking status, body mass index (18.
Background & Aims: COVID-19 is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Studies show that nutrition plays a role in disease prevention and control. So, in this study, we investigate the association between dietary patterns and the severity of COVID-19 in adults.
View Article and Find Full Text PDFJ Cardiovasc Thorac Res
March 2025
Introduction: Premature coronary artery disease (PCAD) has an ascending trend especially in developing countries. This study have investigated the risk factors and severity of developing CAD across various Iranian ethnicities.
Methods: This case-control study was done on 3015 Iranian patients undergoing coronary artery angiography, across highly populated Iranian ethnicities including Bakhtiari, Azari, Qashqai, Arab, Fars, Kurd, Gilak, and Lur.
Background: Despite some evidence on individual eating habits in relation to cardiovascular disease, little is known about the combination of common eating habits in relation to premature coronary artery disease (PCAD).
Objective: We investigated the association between a combined eating habits score (EHS) and PCAD risk.
Methods: In this case-control study, 2022 patients with PCAD and 1063 healthy control were recruited.
Background: Previous studies have shown a connection between diet and mental health. However, there is limited evidence on how emerging diets, particularly the EAT-Lancet reference diet (ELD), relate to depression and anxiety. This study aims to investigate the potential impact of ELD adherence on these mental health conditions.
View Article and Find Full Text PDFThe Mediterranean diet (Med-Diet) is widely recognized for its protective effect in cardiovascular diseases (CVDs), less is known about the associations between health and adherence to the Prime Diet Quality Score (PDQS). This study investigates the relationship between adherence to the Med-Diet and PDQS with the risk of premature coronary artery disease (PCAD) in an Iranian population. A total of 3287 participants were included in this multicenter case-control study across various ethnic groups in Iran, categorized into PCAD cases (n = 2106) and controls (n = 1181).
View Article and Find Full Text PDFBackground: This study aimed to investigate the association between tea and coffee consumption and the 15-year incidence of cardiovascular events and mortality among the Iranian population.
Methods: The present study Data were obtained from the Isfahan Cohort Study (ICS), a prospective cohort study of ≥ 35-year-old healthy adults in central Iran from 2001 to 2017. This study was conducted using baseline data on tea and/or coffee consumption per day/week from ICS to identify the occurrence of any new cardiovascular events, including acute myocardial infarction (AMI), unstable angina (UA), stroke, cardiovascular disease (CVD), sudden cardiac death (SCD), cardiovascular mortality, and all-cause mortality.
Nutr Metab Cardiovasc Dis
July 2025
Background And Aims: Low whole grain food consumption is the leading cause of coronary artery disease (CAD) burden in middle-East countries. However, investigations examining the association of whole and refined grain foods and CAD are scarce in this region. We aimed to investigate the association of whole and refined grain foods with CAD in Iranians with different ethnicities.
View Article and Find Full Text PDFAm J Prev Cardiol
March 2025
Background: The association of novel anthropometrics and novel atherogenicity indices with mortality remains uncertain.
Objective: To compare the association of novel anthropometrics and atherogenicity indices with all-cause, cardiovascular (CVD), and non-CVD mortality in Iranian adults.
Methods: Utilizing data from Isfahan Cohort Study, 5432 participants aged older than 35 years were enrolled.
Evidence has argued about the association between dairy intake and premature coronary artery disease (PCAD) development aimed to be discussed in this study. This case-control study was conducted on 813 individuals with PCAD and 471 healthy controls. The dairy intake of participants was assessed by a validated semi-quantitative food frequency questionnaire.
View Article and Find Full Text PDFDue to the shared risk factors between cardiovascular disease (CVD) and certain cancers such as breast cancer (BC) and colorectal cancer (CRC), our study aimed to assess the CVD risk factors among newly diagnosed patients with BC and CRC. The study utilized baseline data from the ongoing Cardiovascular Events in Breast and Colorectal Cancers (CIBC) cohort study conducted in Isfahan since 2019. Only patients who had recently been diagnosed with BC or CRC and had not undergone any treatment were included in the study.
View Article and Find Full Text PDFInt J Cardiol
February 2025
Background: Premature coronary artery diseases (PCAD) is a major health concern. Finding the potential risk factors for this health issue is crucial for early detection and prevention. This study aimed to evaluate the relation between age at menarche and PCAD presence and severity.
View Article and Find Full Text PDFBackground: Premature coronary artery disease (PCAD) is one of the major health concerns leading to considerable death and disabilities. This study aimed to evaluate the relationship of dietary patterns with risk of PCAD.
Methods: Iran premature coronary diseases (IPAD) is a case-control study consists of 3159 participants.
Background: Iran Premature Coronary Artery Disease (IPAD) is one of the first and largest studies of its kind in Asia that investigates different aspects of premature coronary artery disease (PCAD) in different ethnic groups in multiple cities. In this paper, we aim to describe the IPAD biobank establishment and present some preliminary results of the IPAD study.
Methods: This case-control study was conducted on patients with documented angiography from different ethnicities in more than ten cities of Iran (males aged 60 years and below and females aged 70 years and below).
In the period of increasing prevalence of metabolic disorders such as obesity and diabetes, healthcare professionals are facing significant challenges. Therefore, an accurate global assessment of insulin resistance is of utmost importance. Current medical research is focused on identifying an easily accessible and reproducible gold-standard surrogate marker for insulin resistance.
View Article and Find Full Text PDFPeople with COVID-19 infection continue to have their symptoms or develop new ones after recovery. This is called long-COVID syndrome. We aimed to examine the association of general and abdominal obesity with long COVID.
View Article and Find Full Text PDFBackground: Evidence-based International clinical practice guidelines, universally recommend secondary prevention medications for those with previous cardiovascular disease (CVD). There is limited data on the community use of these medications in the Middle East (ME).
Objectives: This study assesses the use and predictors of evidence based secondary prevention medications in individuals with a history of CVD [coronary heart disease (CHD) or stroke].
Lancet Diabetes Endocrinol
September 2024
Background: Meat consumption could increase the risk of type 2 diabetes. However, evidence is largely based on studies of European and North American populations, with heterogeneous analysis strategies and a greater focus on red meat than on poultry. We aimed to investigate the associations of unprocessed red meat, processed meat, and poultry consumption with type 2 diabetes using data from worldwide cohorts and harmonised analytical approaches.
View Article and Find Full Text PDFBackground: In 2019, a globally sustainable dietary pattern that primarily emphasizes the consumption of plant-based foods was proposed by the EAT-Lancet Commission. However, there is limited evidence regarding the association of this diet with coronary events.
Objectives: To determine the association between the EAT-Lancet Reference Diet (ELD) and premature coronary artery disease (PCAD) risk and its severity.