Resurgence of cholera in Kosti City, Sudan: impact of armed conflict and water supply disruption.

Objectives: This study assesses the magnitude and epidemiological characteristics of the recent cholera resurgence in Kosti City, Sudan, amid ongoing armed conflict and water supply disruptions.

Methods: This was a retrospective cross-sectional study based on hospital records that analyzed cholera surveillance data from Kosti Teaching Hospital from February 20, 2025, to February 24, 2025 (peak period). Epidemiological measures included case fatality rate (CFR) based on the following factors: age, sex, and displacement status.

Mapping of the Antinuclear Autoantibodies in Sudanese patients infected with Human Immunodeficiency Virus after HAART receiving: A cross-sectional study.

It is important to highlight that infection with the human immunodeficiency virus (HIV) may trigger chronic inflammation in people living with HIV/AIDS (PLWHA), impacting to the key immune cells such B and T lymphocytes, leading to development of autoantibodies which might be potential to developed autoimmune phenomenon. This study represent the first investigation in Sudan designed to evaluate and determine the prevalence of Antinuclear autoantibody (ANA) among people living with HIV/AIDS by systematically charaterizing ANA staining patterns; distribution, frequency and their correlation with estimated endpoint titers and interplay of age -sex specific ANA patterns in the context of HIV infection post antiretroviral therapy era. Using Serum samples of one hundred and sixteen (116) HIV-infected patients admitted to two major Voluntary Testing and Counseling (VTC), of the HIV clinical centers at the Military Hospital and Bahri Hospital in Khartoum, Sudan, have been assessed for ANA screening.

A Case Report of Membranoproliferative Glomerulonephritis: Infection-Related or Immune-Related?

Membranoproliferative glomerulonephritis (MPGN) has previously been used as an umbrella term to describe a spectrum of hypocomplementemic glomerular diseases, which are rare causes of end stage kidney disease (ESKD). We present a 22-year-old man with a well-established medical history who had been complaining of 4 days of frothy dark urine, bilateral lower limb swelling, and puffiness on his face. For a month before his presentation, he had many bilateral skin lesions on his lower limbs that were leaking pus.

A case report of metformin-associated lactic acidosis.

Key Clinical Message: Metformin-associated lactic acidosis is a rare but serious complication in patients with type 2 diabetes, especially those with multiple health conditions. Prompt recognition and treatment, including potential renal replacement therapy, are crucial for managing severe acidosis and improving patient outcomes.

Abstract: Metformin (MTF) is commonly prescribed as a first-line treatment for diabetes, effectively preventing microvascular and macrovascular complications.