Publications by authors named "Ning-Xin Guo"
Regiodivergent Ligand-Controlled Cobalt-Catalyzed Reductive Hydroxymethylation of Alkynes with Aqueous Formaldehyde.
Angew Chem Int Ed Engl
September 2025
Allylic alcohols are versatile and essential building blocks in synthetic chemistry, widely used for the preparation of complex molecules, pharmaceuticals, and materials. We report here a regiodivergent reductive hydroxymethylation of terminal alkynes with aqueous formaldehyde to prepare allylic alcohols enabled by visible light photoredox and cobalt dual catalysis. Using readily available, bulk, and cheap aqueous formaldehyde as a simple C1 source, this method allows for the selective production of both linear and branched allylic alcohols in one-step manner.
View Article and Find Full Text PDFHepcidin defense patterns in intestine of mandarin fish (Siniperca chuatsi) against Aeromonas hydrophila infection.
Fish Shellfish Immunol
December 2024
Article Synopsis
- Bacterial septicemia from Aeromonas hydrophila is a significant issue in aquaculture, and this study focuses on how hepcidin, an antimicrobial peptide, helps defend mandarin fish against this pathogen.
- The research analyzed the expression of genes related to iron metabolism and immune response in the fish’s intestine after infection, revealing peak expression times for various genes and changes in iron levels.
- Findings indicate that hepcidin initially limits bacterial growth by regulating iron levels and later modulates immune responses, highlighting its potential role in managing bacterial infections in fish farming.