Publications by authors named "Nicolas Coronel-Restrepo"

Purpose: This expert consensus provides a standardized methodology for interpreting continuous glucose monitoring (CGM) data to optimize diabetes management. It aims to help healthcare professionals recognize glycemic patterns and apply targeted interventions based on real-time glucose metrics.

Methods: A systematic literature review informed expert panel discussions.

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Introduction: Diabetes stands as one of the leading causes of death worldwide. Glucagon-like peptide-1 receptor agonists rank among the most effective medications for lowering blood glucose and body weight, as well as reducing cardiovascular risk in individuals with diabetes. Observational studies complement experimental evidence in new settings, different populations, and real-world healthcare practices.

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Objective: To evaluate the effectiveness and safety of sensor-augmented insulin pump therapy (SAP) in addition to a comprehensive diabetes program on glycated hemoglobin (HbA1c), severe hypoglycemia, ketoacidosis, and the hospital admission rate in patients with type 1 diabetes under real-world settings during a 2-year follow-up.

Methods: This was a retrospective real-life study comparing diabetes control before and after SAP therapy initiation. Patients ≥18 years old with type 1 diabetes were included.

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Objective: To evaluate the effectiveness and safety of sensor-augmented insulin pump therapy (SAP) in addition to a comprehensive diabetes program on glycated hemoglobin (HbA1c), severe hypoglycemia, ketoacidosis, and the hospital admission rate in patients with type 1 diabetes under real-world settings during a 2-year follow-up.

Methods: This was a retrospective real-life study comparing diabetes control before and after SAP therapy initiation. Patients ≥18 years old with type 1 diabetes were included.

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The immune response is complex, multifactorial, individualized and often unpredictable. There are multiple interconnected systems that allow a balance between physiological autoreactive processes and pathological autoimmunity with consequent organ-specific or systemic autoimmune disease. Based on the concept of the autoimmunity mosaic, up to 50% of autoimmune disorders do not have a clear etiological factor.

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Article Synopsis
  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can lead to serious health issues if not properly treated.
  • Researchers conducted a study on patients with SLE who did not respond to standard treatments and were given rituximab (RTX) to induce and maintain remission.
  • The results showed that RTX significantly reduced the need for other immunosuppressive drugs and decreased the number of disease relapses, indicating it is both effective and safe for these patients.
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The primary angiitis of the central nervous system (PACNS) is an entity with a very low incidence and prevalence. It is not clear why the inflammatory process of this entity is limited to the cerebral vasculature without systemic manifestations. Its clinical manifestations are very heterogeneous and make clinical diagnosis difficult.

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