BMC Anesthesiol
September 2025
Background: Advancements in graft selection, surgical and anesthetic techniques have improved the outcomes of pediatric liver transplantation over the last few decades. In this study, we evaluate preoperative factors, the incidence of post-reperfusion syndrome, rejection, and survival among 523 pediatric patients who received whole vs. partial liver transplantation.
View Article and Find Full Text PDFBackground: Liver transplantation (LT) is a critical intervention for pediatric patients with advanced liver failure. This study aimed to assess the impact of perioperative factors on LT outcomes in pediatric patients.
Methods: This retrospective cohort study, conducted from 2010-2020, included 563 pediatric patients who underwent LT in Shiraz, Iran.
The increasing rate of obesity in children and adolescents is alarming, worldwide. This population-based study, conducted in 2024 in Fars Province, Iran, aimed to assess the prevalence of overweight and obesity among primary school students. In the 1st phase, the weight and height of 9853 students who were selected by multi-stage cluster random sampling from 36 districts were measured standardly.
View Article and Find Full Text PDFBackground: Sarcopenia is an age-related condition characterized by progressive loss of muscle mass, strength, and function, significantly impairing quality of life in older adults. This study investigated the association between three TP53 genetic variants (rs1625895, rs1042522, and rs17878362) and their haplotypes with Bioelectrical Impedance Analysis (BIA) parameters and nutritional status in elderly Iranian individuals.
Methods And Results: The TP53 rs1625895 variant showed a significant association with nutritional status (P = 0.
Background: In the female population, breast cancer is the most common cancer and a leading cause of cancer death. This study was designed to investigate the geographical pattern of breast cancer risk in different counties of Fars province in the south of Iran from 2001 to 2018.
Methods: In this historical cohort study, data of Shiraz Population-Based Cancer Registry between 2001 and 2018 was used.
Iran J Med Sci
April 2025
Background: Effective pain management is crucial in septorhinoplasty and remains a significant challenge. This study investigated the effect of ketorolac and paracetamol on pain control in septorhinoplasty patients and assessed their efficacy in reducing the need for rescue analgesics.
Methods: This double-blind randomized clinical trial was conducted at Madar-Koodak Hospital (Shiraz, Iran), in 2022.
Int J Pediatr Otorhinolaryngol
March 2025
Objectives: Ropivacaine local injection is a preventative management option for post-adenotonsillectomy pain. The effectiveness of this approach varies depending on the time of drug administration. This study is aimed to evaluate pre-emptive effect of administration of Ropivacaine before vs.
View Article and Find Full Text PDFBackground: Acute renal colic has been challenging and has brought many concerns for physicians and patients for centuries. This study aimed to evaluate the analgesic effect and safety of a combination of papaverine and ketorolac against ketorolac and placebo in treating acute renal colic.
Methods: This randomized clinical trial was performed in patients with renal colic from May 2018 to May 2020 in Ahvaz, Iran.
Background: Diabetes mellitus is a widely distributed endocrine disorder in the world. Altered reproductive function is a notable long-term consequence of type 1 diabetes mellitus (T1DM). In the current study, we assessed the effects of soya milk containing Lactobacillus casei and omega-3 on stereology of testes in type 1 diabetic rats.
View Article and Find Full Text PDFBackground: Gabapentin is an anticonvulsant used for managing neuropathic pain. Its effectiveness and dosing strategies for postoperative pain, particularly in open shoulder rotator cuff repair, are still debated. This study assesses gabapentin's impact on postoperative pain intensity in open rotator cuff repair.
View Article and Find Full Text PDFIran J Med Sci
September 2024
J Extra Corpor Technol
September 2024
Background: Guillain-Barre Syndrome (GBS) is the most prevalent acute peripheral polyneuropathy disorder. The disparities between populations and variations in the major risk factors highlight the importance of country-specific studies. This study aimed to report clinical characteristics and outcomes of ICU-admitted patients with GBS in an academic medical center in Iran.
View Article and Find Full Text PDFIran J Med Sci
July 2024
Background: The management of preoperative anxiety in pediatric patients, as well as its implications, has remained challenging for anesthesiologists. In this study, we compared the safety and efficacy of intranasal dexmedetomidine, midazolam, and ketamine as surgical premedication in children.
Methods: This double-blinded randomized clinical trial was conducted at two tertiary hospitals in January 2014, on 90 children aged between 2-7 years old.
Background: The effectiveness of continuous wound infiltration (CWI) as a postoperative pain-control technique has been shown in many surgical procedures. This study investigates the effect of CWI of local anesthetic on postoperative pain control in intertrochanteric fracture patients undergoing hip nailing surgery.
Methods: In this randomized clinical trial, 48 patients who were scheduled for hip nailing surgery were randomly assigned to receive ( = 24) or not receive ( = 24) bupivacaine infusion through a catheter inside the surgical wound, postoperatively.
Objectives: Numerous studies have been conducted to investigate the effects of preoperative hyponatremia on survival after liver transplantation. The variable findings underscore the necessity for performing a systematic review to elucidate the potential effects of preoperative hyponatremia.
Materials And Methods: We searched PubMed, Scopus, Web of Science, Science Direct, Cochrane Library, and reference lists of articles for observational cohort studies that reported association between preopera-tive hyponatremia and survival after liver transplant in adults regardless of publication year.
Objectives: The purpose of this study was to determine the therapeutic effect of the Punica granatum (PG) flower on recurrent aphthous stomatitis in comparison with corticosteroid therapy.
Materials And Methods: This cross-over randomized clinical trial was conducted on the patients who had been referred to Shiraz Dental School for their RAS in 2021. All the participants used both P.
Iran J Med Sci
May 2024
Background: There have been few studies on the effect of Kegel exercises on the treatment of functional constipation in children. Hence, the present study investigated the add-on role of Kegel exercises in children with functional constipation.
Methods: This clinical trial was conducted on children with functional constipation, according to Rome IV, who were referred to the pediatric department of Imam Reza Clinic (Shiraz, Iran) in 2022.
Background: Despite the beneficial effects, RBC transfusion can be associated with infectious and non-infectious complications in critically ill patients.
Objectives: Investigate current RBC transfusion practices and their effect on the clinical outcomes of patients in intensive care units (ICUs).
Design: Retrospective observational study.
Purpose: Prolonged mechanical ventilation (MV) subjects multiple trauma patients to ventilator-induced diaphragmatic dysfunction. There is limited evidence on the predictive role of diaphragm ultrasound (DUS) for weaning success in multiple trauma patients. Therefore, we evaluated Ultrasound of the diaphragm as a valuable indicator of weaning outcomes, in trauma patients.
View Article and Find Full Text PDFSurg Laparosc Endosc Percutan Tech
April 2024
Objective: Nausea and vomiting after surgery are the most common complications. Therefore, we performed this study to compare the effect of ondansetron and haloperidol on nausea and vomiting after laparoscopic cholecystectomy.
Patients And Methods: In this randomized clinical trial, 60 patients candidates for elective laparoscopic cholecystectomy were allocated to haloperidol (0.
Objectives: This study aimed to compare the efficacy of labetalol and lidocaine in tympanoplasty surgery, specifically evaluating their impact on hemodynamic changes and perioperative outcomes.
Methods: A randomized controlled trial was conducted with 64 patients scheduled for tympanoplasty. Patients were randomly assigned to receive either 0.
Pain Res Manag
January 2024
Background: The erector spinae plane (ESP) block is a novel approach to minimizing postoperative pain. We investigated the efficacy and side effects of the ultrasonography-guided bilateral ESP block in reducing pain in the first 24 hours after lumbar laminectomy.
Materials And Methods: We conducted a single-blind (statistical analyst and those responsible for recording patient information postoperation were unaware of the study groups) randomized clinical trial on 50 patients aged 18 to 65 with American Society of Anesthesiology (ASA) class I or II physical status scheduled for lumbar laminectomy surgery at Shahid Chamran Hospital, Shiraz, Iran.