The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis.

Autophagy is a vital process that enables plants to adapt to various environmental changes. During heat stress (HS), misfolded and denatured proteins accumulate in cells, necessitating autophagy for their removal. Here, we show that a core autophagy component ATG8a is targeted for degradation via the Arg/N-degron pathway.

Resistive gas sensors for the detection of NHgas based on 2D WS, WSe, MoS, and MoSe: a review.

Transition metal dichalcogenides (TMDs) with a two-dimensional (2D) structure and semiconducting features are highly favorable for the production of NHgas sensors. Among the TMD family, WS, WSe, MoS, and MoSeexhibit high conductivity and a high surface area, along with high availability, reasons for which they are favored in gas-sensing studies. In this review, we have discussed the structure, synthesis, and NHsensing characteristics of pristine, decorated, doped, and composite-based WS, WSe, MoS, and MoSegas sensors.

Identifying the external N and Hg inputs to the estuary ecosystem based on the triple isotopic information (δN, ΔO and δO).

The supply and sources of N and Hg in the Geum estuary of the western coast of Korea were evaluated. Triple isotope proxies (δN, ΔO and δO) of NO combined with conservative mixing between river and ocean waters were used to improve isotope finger-printing methods. The N pool in the Geum estuary was primarily influenced by the Yellow Sea water, followed by riverine discharge (821 × 10 mol yr) and atmospheric deposition (51 × 10 mol yr).

Poly-L-Lactic Acid Fillers Improved Dermal Collagen Synthesis by Modulating M2 Macrophage Polarization in Aged Animal Skin.

Poly-L-lactic acid (PLLA) fillers correct cutaneous volume loss by stimulating fibroblasts to synthesize collagen and by augmenting the volume. PLLA triggers the macrophage-induced activation of fibroblasts that secrete transforming growth factor-β (TGF-β). However, whether M2 macrophage polarization is involved in PLLA-induced collagen synthesis via fibroblast activation in aged skin is not known.

Pathogen-induced autophagy regulates monolignol transport and lignin formation in plant immunity.

The evolutionary plant-pathogen arms race has equipped plants with the immune system that can defend against pathogens. Pattern-triggered immunity and effector-triggered immunity are two major branches of innate immunity that share immune responses, including oxidative bursts, transcriptional reprogramming, and cell wall modifications such as lignin deposition. In a previous study, we reported that lignin rapidly accumulates in pathogen-infected leaves and acts as a mechanical barrier, spatially restricting pathogens and cell death.

The transcription factor ORA59 exhibits dual DNA binding specificity that differentially regulates ethylene- and jasmonic acid-induced genes in plant immunity.

Jasmonic acid (JA) and ethylene (ET) signaling modulate plant defense against necrotrophic pathogens in a synergistic and interdependent manner, while JA and ET also have independent roles in certain processes, e.g. in responses to wounding and flooding, respectively.

The Arabidopsis R2R3 MYB Transcription Factor MYB15 Is a Key Regulator of Lignin Biosynthesis in Effector-Triggered Immunity.

Lignin, a major component of the secondary cell wall, is important for plant growth and development. Moreover, lignin plays a pivotal role in plant innate immunity. Lignin is readily deposited upon pathogen infection and functions as a physical barrier that limits the spread of pathogens.

Lignin-based barrier restricts pathogens to the infection site and confers resistance in plants.

Pathogenic bacteria invade plant tissues and proliferate in the extracellular space. Plants have evolved the immune system to recognize and limit the growth of pathogens. Despite substantial progress in the study of plant immunity, the mechanism by which plants limit pathogen growth remains unclear.

An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164.

Hypersensitive response (HR) is a form of programmed cell death (PCD) and the primary immune response that prevents pathogen invasion in plants. Here, we show that a microRNAmiR164 and its target gene NAC4 (At5g07680), encoding a NAC transcription factor, play essential roles in the regulation of HR PCD in Arabidopsis thaliana. Cell death symptoms were noticeably enhanced in NAC4-overexpressing (35S:NAC4) and mir164 mutant plants in response to avirulent bacterial pathogens.

Novel film patterned retarder utilizing in-plane electric field.

Conventional film patterned retarder (FPR) production requires a photo-alignment layer and a UV exposure process through a patterned wire-grid photo-mask, increasing the cost as well as limiting the resolution of FPR. We proposed a novel method for the fabrication of FPR without using the alignment layer and the photo-mask. Reactive mesogen (RM) was coated on a base film, and then the substrate with 2-domain interdigitated electrodes was contacted over the RM layer.

F-18 FDG positron emission tomography findings in primary pancreatic lymphoma.

The usefulness of F-18 2'-deoxy-2-fluoro-D-glucose (FDG) positron emission tomography (PET) has been well established for lymphoma staging. Although involvement of the pancreas occurs in more than one third of patients with non-Hodgkin lymphoma, primary lymphoma of the pancreas accounts for less than 1% of extranodal non-Hodgkin lymphomas. Because patients with primary pancreatic lymphoma require a different therapeutic approach and have a better prognosis than those with pancreatic adenocarcinoma, the accurate diagnosis is important.