Publications by authors named "Muhannad Alsyouf"
Objectives: To comprehensively review the literature on paratesticular tumors and to develop a new management algorithm.
Methods: A systematic review was conducted from 1980 to 2024 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A search was performed on PUBMED to identify studies investigating paratesticular tumors, limited to cases >16 years of age.
Purpose: Recent clinical trials on primary retroperitoneal lymph node dissection (RPLND) for testicular seminoma highlight inaccuracies in conventional imaging for lymph node staging. Limited data exist on the accuracy of positron emission tomography (PET) in patients with chemotherapy-naïve testicular seminoma. We evaluated the accuracy of 18F-fluorodeoxyglucose (FDG) PET for the detection of metastatic disease within the SEMS (Surgery in Early Metastatic Seminoma) trial.
View Article and Find Full Text PDFMycotic pseudoaneurysms are rare dilations of the arterial wall caused by infection. We present a case of a 62-year old man with disseminated tuberculosis and a large mycotic pseudoaneurysm involving the main renal artery and vein. Despite being on appropriate rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE) therapy, the pseudoaneurysm grew with increasing concern for potential rupture.
View Article and Find Full Text PDFPurpose: A midline extraperitoneal approach for retroperitoneal lymph node dissection (EP-RPLND) has been associated with decreased morbidity compared to the transperitoneal approach. We aimed to review our 11-year experience in patients with germ cell tumors (GCTs) who underwent EP-RPLND at a single institution.
Materials And Methods: All patients with GCT who underwent EP-RPLND between 2010 and 2021 were reviewed.
Introduction: Opioid dependence represents a public health crisis and can be observed after outpatient urologic procedures. The purpose of this study was to evaluate the risk of persistent opioid usage after radical orchiectomy for testicular cancer.
Materials And Methods: The TriNetX Research network database was queried for men between 15 and 45 years undergoing radical orchiectomy for a diagnosis of testicular cancer.
Article Synopsis
- The study aimed to evaluate how common early postoperative acute kidney injury (EP-AKI) is in patients who undergo radical cystectomy for bladder cancer and what factors might predict its occurrence.
- Out of 435 patients reviewed, 26% experienced EP-AKI, which was linked to longer hospital stays, increased complication rates, and higher readmission rates.
- Key predictors for EP-AKI included the need for blood transfusions during surgery and the type of urinary diversion performed post-surgery.
Testicular germ cell tumors (GCTs) are the most common malignancy among young males. The majority of patients present with early stages of the disease that are highly curable. For stage I disease, treatment options include surveillance, retroperitoneal lymph node dissection (RPLND), and systemic chemotherapy.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to determine if restaging transurethral resection of bladder tumor (TURBT) is necessary for high-risk nonmuscle invasive bladder cancer (NMIBC) after initial TURBT using blue light (BL) technology.
- Researchers reviewed data from the Cysview registry of patients with NMIBC who had TURBT followed by a restaging TURBT within 8 weeks, comparing outcomes between initial surgeries done with blue light versus white light (WL).
- Results showed no significant differences in rates of residual tumors or upstaging to muscle invasive disease between the two groups, concluding that restaging TURBT remains essential regardless of the initial technique used.
Objective: To examine the oncological outcomes and recurrence patterns in patients with no residual disease at the time of radical cystectomy (RC).
Methods: A retrospective review of our IRB-approved bladder cancer database identified patients who underwent RC between 2000 and 2019 and were found to have no residual disease (pT0N0), either following neoadjuvant chemotherapy (NAC) or transurethral resection (TURBT) alone. The primary outcome was recurrence-free survival (RFS).
Introduction: Perivesical lymph nodes were added to the 8th edition of American Joint Committee on Cancer (AJCC) staging for bladder cancer. Currently, these nodes are inconsistently evaluated at the time of radical cystectomy. The objective of this study was to provide a detailed anatomic evaluation of perivesical lymph nodes.
View Article and Find Full Text PDFArticle Synopsis
- Upper tract urothelial carcinoma (UTUC) is a type of cancer that makes up 5-10% of all urothelial tumors, where radical nephroureterectomy (RNU) is the standard treatment, showing promising outcomes with robotic techniques compared to traditional open surgery.
- The "Keyhole" technique introduced for robotic RNU allows for improved visualization and precise excision of the distal ureter and bladder cuff without needing additional surgical incisions, enhancing oncological safety.
- A study involving 10 patients showed that this technique resulted in minimal complications and a low rate of bladder recurrence, demonstrating its effectiveness in managing high-grade UTUC.
Purpose Of Review: Retroperitoneal lymph node dissection (RPLND) and retroperitoneal tumor resection for germ cell cancer are complex operations requiring experience and expertise in surgical techniques necessary to achieve complete resection while minimizing morbidity. This article reviews the intricacies of RPLND for testis cancer.
Recent Findings: Surgical management of advanced testis cancer begins with an intimate understanding of retroperitoneal anatomy and the various techniques necessary to safely extirpate tumors.
Introduction: Obstructing stones with infection represent a true urologic emergency requiring prompt decompression. Historically the systemic inflammatory response syndrome (SIRS) criteria has been used to predict outcomes in patients with sepsis. The quick Sequential Organ Failure Assessment (qSOFA) score has been proposed as a prognostic factor in patients with acute pyelononephritis associated with nephrolithiasis.
View Article and Find Full Text PDFArticle Synopsis
- Management strategies for clinical stage II seminoma are shifting towards reducing long-term side effects while still ensuring effective treatment outcomes.
- This review highlights the emerging role of surgery, specifically retroperitoneal lymph node dissection, as a potential first-line treatment for low-volume metastatic seminoma patients.
- Early results from studies like SEMS and PRIMETEST indicate that this surgical approach may lead to better outcomes compared to traditional methods like chemotherapy and radiotherapy, which can have severe long-term health impacts.