The association of endothelial nitric oxide synthase () gene polymorphisms and diabetic retinopathy among patients with type 2 diabetes: A case-control study.

Purpose: Diabetic patients experience chronic hyperglycemia that increases oxidative stress by enhancing free radical formation and nitric oxide (NO) production. Genetic mutations in the endothelial nitric oxide synthase () enzyme gene affect the levels of NO formation. These mutations, together with chronic hyperglycemia, may increase the risk of diabetic retinopathy (DR) development and/or DR progression as a complication of diabetes.

Unilateral Corneal Ectasia After Bilateral Transepithelial Photorefractive Keratectomy.

We present the case of a 23-year-old male who experienced vision loss in his left eye 15 months after undergoing bilateral transepithelial photorefractive keratectomy (T-PRK). Despite the absence of any significant preoperative topographical risk factors in either eye, corneal ectasia was later confirmed in the left eye, while the right eye remained normal. Subtle asymmetry in topometric indices and a borderline high Index of vertical asymmetry (IVA) reading suggested the possibility of early subclinical keratoconus, potentially increasing the risk of post-refractive ectasia.

Association Between Keratoconus and Shoulder Dislocation: A Cross-Sectional Study.

Introduction Few studies have highlighted the correlation between shoulder dislocation and keratoconus (KC). This study aimed to examine the association between KC and shoulder dislocation using patients with KC and matched controls. Methods This cross-sectional study was conducted at Jordan University Hospital.

Awareness and knowledge about glaucoma among patients attending outpatient clinics of Jordan University Hospital.

Purpose: To evaluate the level of awareness and knowledge about glaucoma among Jordanians and determine the relationship between glaucoma knowledge and selected variables.

Methods: This was a descriptive and cross-sectional study conducted at a central hospital. Face-to-face interviews were performed to obtain sociodemographic data and information about glaucoma from Jordanian participants attending different outpatient clinics of Jordan University Hospital (JUH).

Lack of relationship between Alu repetitive elements in angiotensin converting enzyme and the severity of diabetic retinopathy.

Background: Angiotensin-converting enzyme (ACE) stimulates angiogenesis that leads to the development of diabetic retinopathy (DR). Alu repetitive elements in ACE gene increase the expression of this enzyme. We investigated the frequency of Alu repetitive elements, insertion/deletion (I/D) polymorphism, in angiotensin-converting enzyme among diabetic retinopathy patients and whether this polymorphism is associated with the severity of retinopathy in Jordanians with type 2 diabetes.

The relationship between aldose reductase gene C106T polymorphism and the severity of retinopathy in Type 2 diabetic patients: A case-control study.

Background: Hyperglycemia over-activates glucose reduction to sorbitol by aldose reductase (ALR) leading to osmoregulation disruption and cellular damage that cause diabetic complications. We investigated the association of C106T polymorphism of gene with the severity of diabetic retinopathy (DR) in Jordanian Type 2 diabetic patients in this case-control study at the Ophthalmology clinic of the National Centre of Diabetes, Endocrinology, and Genetics.

Materials And Methods: A total of 277 subjects participated in the study (100 diabetics without retinopathy, 82 diabetics with retinopathy, and 95 controls).

Autoimmune Thyroid Disease and Keratoconus: Is There an Association?

Purpose: The association between autoimmune diseases and keratoconus (KC) has been proposed based on previous retrospective studies and case reports. The aim of our study is to investigate whether KC is associated with autoimmune thyroid disease A comparative study was conducted on 131 adult subjects from September 2015 to May 2017 at Jordan University Hospital, Amman, Jordan. Subjects were classified into 2 groups: subjects with autoimmune thyroid disease, including Graves' disease and Hashimoto's thyroiditis ( = 68), and a healthy group for comparison ( = 63).

Platelet lysate promotes re-epithelialization of persistent epithelial defects: a pilot study.

Purpose: To study the use of autologous platelet lysate prepared in a standardized method for the healing of persistent corneal epithelial defects (PED).

Study Design: Clinical and experimental investigation.

Methods: In this prospective pilot study (ClinicalTrials.

Keratoconus Asymmetry between Both Eyes Based on Corneal Tomography.

Purpose: To characterize the asymmetry between both eyes in patients with keratoconus based on corneal tomography.

Materials And Methods: All patients with keratoconus who presented to the eye clinic at Jordan University Hospital between January 2008 and November 2011 were included in the study. Using computerized corneal tomography, the keratometric values and indices of both eyes of participants with keratoconus and normal controls were compared.

Prevalence of blindness and diabetic retinopathy in northern Jordan.

Purpose: To estimate the prevalence of blindness, visual impairment, diabetes, and diabetic retinopathy in north Jordan (Irbid) using the rapid assessment of avoidable blindness and diabetic retinopathy methodology.

Methods: A multistage cluster random sampling technique was used to select participants for this survey. A total of 108 clusters were selected using probability proportional to size method while subjects within the clusters were selected using compact segment method.

Topographic characteristics of keratoconus among a sample of Jordanian patients.

Aim: To identify topographic characteristics of keratoconus in a Jordanian sample.

Methods: This study characterized 210 corneas affected with keratoconus presenting to Jordan University Hospital. Patients were diagnosed based on clinical examinations and Pentacam imaging.

Ocular manifestations of Behçet's disease in Jordanian patients.

Purpose: To study the prevalence, manifestations and severity of ocular involvement of Behçet's disease in Jordanian patients.

Methods: The study population consisted of 43 patients diagnosed to have Behçet's disease through Rheumatologist's examinations conducted at Jordan University Hospital between January 2002 and July 2009. The sample involved patients who displayed ocular manifestations.

Intravitreal bevacizumab in the treatment of diabetic ocular neovascularization.

Purpose: To evaluate the efficacy of intravitreal bevacizumab for treating diabetic retinal and/or iris neovascularization.

Methods: Consecutive, prospective, interventional case series study of 60 eyes with diabetic retinal and/or iris neovascularization. Patients had a complete ocular examination before receiving 1.

Ferrara ring segments implantation for treating keratoconus.

Aim: To investigate the efficacy of Ferrara rings (FR) implantation in the treatment of keratoconus.

Methods: It was a retrospective case series descriptive study. The sample was comprised of 50 patients 79 eyes diagnosed with progressive keratoconus.

Pseudoexfoliation syndrome at Jordan University Hospital.

Purpose: This study aimed to estimate the prevalence of pseudoexfoliation syndrome (PXS) and analyse its association with particular ocular diseases in patients attending the Department of Ophthalmology at Jordan University Hospital.

Methods: A total of 1195 consecutive patients, aged 40-90 years, who attended the Department of Ophthalmology at Jordan University Hospital between December 2005 and March 2007 were included in the study. Each patient underwent complete ophthalmic evaluation, including: relevant history; visual acuity testing; slit-lamp examination, applanation tonometry, gonioscopy and dilated fundus examination.

Risk Factors for Diabetic Retinopathy among Jordanian Diabetics.

Purpose: To identify the risk factors associated with diabetic retinopathy among diabetic patients at Jordan University Hospital.

Methods: A total of 986 patients with diabetes mellitus were assessed at Jordan University Hospital. The assessment included detailed relevant history, complete medical and ophthalmic evaluation.

Late opacification of a hydrophilic acrylic intraocular lens.

Cataract extraction and intraocular lens implantation is considered to be a safe procedure in most cases. However, the new advances in the surgical technique namely phacoemulsification and hence the increased use of foldable intraocular lenses have given rise to new complications including late opacification of intraocular lenses. In this case we report late opacification of a foldable hydrophilic acrylic intraocular lens and the surgical technique for its exchange.

Argon laser: a modality of treatment for trichiasis.

The purpose of this study is to evaluate the success rate and safety of argon laser photocoagulation as a modality of treatment for symptomatic trichiasis in a Middle Eastern country (Jordan). This simple descriptive study included 54 patients (68 lids) with symptomatic trichiasis. They were treated with argon laser and followed over 8 month period.