Publications by authors named "Motahareh Kheradmand"

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for managing pain and inflammatory conditions. However, their usage patterns and associated risk factors in the general population remain insufficiently understood, particularly in the Iranian context. This study aims to explore the epidemiological and clinical factors associated with NSAID consumption in a population-based cohort.

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Background: Chronic kidney disease (CKD) is a well-established public health concern worldwide. Considering the asymptomatic nature of early-stage CKD and its importance, we aimed to investigate the prevalence of undiagnosed stage 3 CKD in a large-scale, population-based cohort study.

Methods: In this cross-sectional study, data collected during the enrollment phase of the Tabari Cohort Study (TCS) were utilized.

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Anemia is a global public health concern. It is more prevalent in women and previous studies have mostly been limited to pregnant women. Therefore, this study aimed to investigate the association between gravidity and anemia in a subset of women enrolled in the Tabari Cohort study.

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Objective: We compared non-laboratory models' efficacy with standard laboratory-based model in identifying high-risk populations for cardiovascular disease (CVD) in resource-limited settings.

Methods: A national sample of 121 672 individuals aged 40-70 from the PERSIAN cohort was analyzed. Non-laboratory models, including the World Health Organization (WHO) and Iranian pooled-cohort CVD mortality models, were compared with the WHO laboratory-based model.

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Background: Cigarette smoking stands as a prominent contributor to global mortality rates, and its impact spans both immediate and long-term effects on hematological parameters; however, in addition to controversial results in previous studies, its effect on novel inflammatory indices has yet to be thoroughly investigated. Thus, this study aims to assess the impact of various smoking profiles on total white blood cell (WBC) count, WBC differentials, and novel hematologic-inflammatory indices among males.

Methods: This cross-sectional study was conducted on 4039 male adults from the enrollment phase data of the TABARI cohort population in Iran.

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Background: Anemia is a common blood disorder in developing countries and is associated with diseases such as diabetes, as well as cardiovascular and pulmonary diseases. This study aimed to investigate the relationship between anemia and anthropometric profiles in the Tabari cohort population. A case-control study.

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Background: Undiagnosed hypertension (HTN) and diabetes mellitus (DM) are major public health challenges worldwide. We aimed to investigate the prevalence of undiagnosed HTN and DM, and their correlates, in a large-scale population-based cohort study.

Methods: In this cross-sectional study, data collected during the enrollment phase of the Tabari Cohort study (TCS) were utilized.

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Article Synopsis
  • Anemia is a significant public health issue, contributing to high rates of illness and death, prompting a study on its prevalence and related factors in the Tabari cohort population.
  • The study involved over 10,000 participants, revealing that 13.4% were diagnosed with anemia, with factors such as gender, urban residence, social economic status, and drug abuse affecting the likelihood of being anemic.
  • The findings indicate a higher odds of anemia for females, urban dwellers, and individuals with poor socioeconomic conditions, alongside various health indicators such as BMI and cholesterol levels.
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Article Synopsis
  • The study investigated the combined occurrence of diabetes mellitus (DM) and thyroid dysfunction (TD) in a population of adults aged 35-70 in Iran, with a significant percentage of participants included.
  • The prevalence of thyroid dysfunction among those with Type 2 diabetes was found to be 13.2%, while the prevalence of Type 2 diabetes in those with thyroid dysfunction was 9.2%.
  • Key risk factors for this comorbidity included being female, older age, smoking, higher waist circumference, low HDL cholesterol, and low physical activity levels.
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Background: Antituberculosis drugs may cause mild, moderate or severe adverse drug reactions (ADR) leading to poor compliance. Description of the pattern of ADR and their related factors can help tuberculosis (TB) control program as part of the WHO programs. This study aims to investigate the incidence of ADR and associated factors among TB patients in northern Iran.

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Article Synopsis
  • * Smokers had lower levels of high-density lipoprotein (HDL) and higher levels of low-density lipoprotein (LDL) compared to non-smokers, with the risk increasing with the number of cigarettes smoked daily.
  • * The findings emphasize the need for smoking cessation, as high smoking intensity significantly worsens lipid profiles, raising the odds of related health risks.
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Introduction: A large portion of the world's population has asthma. This study aimed to ascertain asthma prevalence and related factors in the Tabari cohort study (TCS).

Methods: The TCS included 10,255 35-70-year-olds from urban and mountainous Sari (northern Iran) between June 2015 and November 2017.

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Objective: Stress is known as a conventional risk factor of cardiovascular disease. Nurses work in stressful environment and could be one of the target populations to be assessed for cardio metabolic risk factor. This study aimed to identify the association between perceived stress and cardio-metabolic risk factors in nurses who are prone for various metabolic diseases.

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Background: Psoriasis is nowadays regarded as a systemic inflammatory disorder. Among the topicals, vitamin D derivates are often applied on the skin for their anti-inflammatory and immune-modulatory properties. Vitamin D serum levels in psoriasis (PsO) patients are still debated and an eventual depletion may offer the rational to integrate anti-psoriatic therapies with oral vitamin D.

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Objectives: The association between age at menarche and higher-risk cardiometabolic factors is controversial and more strands of evidence are required. Therefore, in this study, we aimed to investigate the effect of early menarche on cardiometabolic profile in a large-scale cohort population.

Study Design: Data collected in the enrollment phase of the Tabari cohort study were utilized for the present study.

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Background And Aim: The coronavirus disease 2019 (COVID-19) pandemic has to date overwhelmed the survivors and the general population. The present study aimed to compare the mental health status and the COVID-19 event impact between the survivors and the general population in Mazandaran Province, Northern Iran.

Design: A web-based cross-sectional survey was used.

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Background: This study aims to investigate the situation of sleep profile and its related factors in the Tabari Cohort Tabari (TCS) population.

Methods: The information of 10255 of the Tabari cohort population in the enrolment phase was used in this study. The sleep profile data was collected and recorded by trained questioners.

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Background: White Blood Cells (WBC) can be a useful marker to predict diabetes. In this study, we aimed to investigate the association between WBC count with type 2 diabetes in a large-scaled population-based cohort study.

Methods: In the present study we used a subset of data collected in enrolment phase of Tabari cohort study.

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Background: The association between liver enzymes and metabolic syndrome (MetS) has been evaluated in several studies with different results. The purpose of this study is to determine the association between the serum levels of these liver enzymes and MetS in Tabari cohort population.

Method: In this case-control study, data collected from the enrolment phase of the Tabari cohort population have been used.

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Association between the serum vitamin D level and disability of patients with multiple sclerosis (MS) has been investigated during several researches. However, these studies reported different results. The current study aims to estimate the correlation between the concentrations of 25 (OH) vitamin D and the level of disability among MS patients.

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Background And Aims: The purpose of the present study was to investigate the association of gravidity and age at first pregnancy with metabolic syndrome in a large-scale, population-based cohort study in Iran.

Methods: The present secondary analysis was conducted on a subset of the population (5739 women with at least one pregnancy) enrolled in the Tabari cohort study. Reproductive history was collected using a structured questionnaire.

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Background: Metabolic syndrome is defined by co-incidence of multiple metabolic disorders such as central obesity, high triglycerides, low HDL, hyperglycemia and high blood pressure, which increases the risk of cardiovascular disease and diabetes. The aim of this study was to estimate the prevalence of metabolic syndrome using Adult Treatment Panel III (ATP-III), International Diabetes Federation (IDF) and Iranian criteria in large-scaled population based cohort study and to determine the concordance between these criteria.

Methods: In the present study all information collected in Tabari cohort study(TCS) were utilized.

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Background: Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk factors on its prevalence in the Tabari cohort study (TCS) population.

Methods: The enrollment phase of TCS was performed between June 2015 and November 2017.

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Objectives: The age of menopause is affected by several factors. In this study we aimed to identify the age of natural menopause and its related factors in a large-scale population-based cohort in Iran.

Methods: In this study, a subset of data collected during the enrollment phase of the Tabari cohort study was utilized.

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Objectives: Different factors are responsible for the silent epidemic of diabetes mellitus in developing and developed countries. This study aimed to determine the role of demographic factors, lipid profile, family history (the estimation of genetic association) and anthropometric factors on diabetes onset.

Methods: Data from the enrolment phase of the Tabari Cohort study was applied for this study and included 10,255 participants aged between 35-70 years.

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