Publications by authors named "Mona Hashim"

Context: Studies findings have suggested that vitamin D plays a critical role in maintaining overall health, including having a potential impact on gut microbiota composition, which influences various physiological processes.

Objectives: To examine the effects of vitamin D supplementation on human gut microbiota composition and diversity by analyzing findings from randomized controlled trials (RCTs).

Data Sources: A comprehensive search of the MEDLINE, Web of Science, Scopus, and the Cochrane Library electronic databases was conducted to identify relevant studies published from January 1, 2015, to November 30, 2024.

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Background: The utilization of social media (SM) is widespread among young adults; nevertheless, there is limited understanding regarding their use for obtaining nutrition information. This study aimed to examine the characteristics and determinants of using SM for nutrition information amongst young adults in the United Arab Emirates (UAE).

Methods: A multicomponent questionnaire was emailed to all students attending the largest university in the country.

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Background: Investigating consumer food choice motivations is crucial for planning effective policies and targeted interventions. This study aimed to examine the food choice motivations and perceptions of healthy eating among adults in the United Arab Emirates (UAE) and to segment consumers based on their motivations.

Methods: A web-based, cross-sectional study was conducted among adults in the UAE (n = 1209).

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CBFB encodes the core-binding factor β subunit, a small protein which heterodimerises with RUNX1-3 and activates transcription of genes important in bone development. Recently, five families with cleidocranial dysplasia (CCD) were identified harbouring presumed loss of function variants in CBFB. Prompted by a multidisciplinary team review of an affected mother and daughter from the 100 000 Genomes Project with genetically unsolved CCD, we inspected read alignments and identified a deletion-inversion-deletion that removes the first two exons of CBFB.

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Background: To evaluate breastfeeding and complementary feeding practices and their determinants among infants and young children in the United Arab Emirates using the 2021 WHO/UNICEF IYCF guidelines.

Methods: The Mother and Infant Study Cohort (MISC), is a prospective study of mothers recruited in their third gestational trimester and followed with their infants up to 18 months of age (n = 167). Data were collected at 3rd trimester, delivery, 2, 6, 12, and 18 months postpartum via questionnaires, review of medical records, anthropometric measurements, and 24-hour dietary recalls of the child's intake at 6, 12, and 18 months.

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: The escalating global demand for meat, as a sequela of population growth, has led to unsustainable livestock production, resulting in a host of environmental and food security concerns. Various strategies have been explored to mitigate these issues, including the introduction of a novel food product, cultured meat. Cultured meat is not yet commercially available, yet public perceptions are already taking shape.

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Background: Accurate growth assessment of preterm infants is essential in guiding medical care and suitable nutritional interventions. Currently, different growth references are used across hospitals in the United Arab Emirates (UAE). This study aims to compare the INTERGROWTH-21st standards with Fenton growth references regarding birth size classification and at the time of discharge in a sample of preterm infants in the UAE.

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Background: Substantial evidence embraced the nutrition competence of the Mediterranean diet (MD) as a healthy model for decreasing the risk of chronic diseases and increasing longevity, with the bonus of ensuring environmental sustainability. Measuring adherence to this diet is marginally investigated in the Arabian Gulf region, an area away from the Mediterranean region. The current study aimed to assess the MD adherence among adults in Sharjah/the United Arab Emirates (UAE), and to identify the most influential predictors for MD adherence among the study participants.

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Article Synopsis
  • This study investigates the role of inversions—structural variants that involve the rearrangement of DNA—in genetic diseases, using data from 33,924 families involved in the 100,000 Genomes Project.
  • Researchers identified 47 ultra-rare rearrangements, including de novo inversions, in genes linked to disease, with analyses correlating genetic findings to clinical outcomes in some cases, including a specific diagnosis for three family members.
  • The findings suggest that while inversions are less common in genetic diseases compared to other structural variants, they can significantly contribute to the etiology in approximately 1 in 750 families with rare conditions.
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Introduction: This cross-sectional study aimed to assess Online food delivery applications (OFDA) usage trends among adolescent users in the United Arab Emirates (UAE), focusing on their perceptions of healthy food options and food safety ( = 532).

Methods: Sociodemographic information, frequency of OFDA use, factors affecting food choices, and perceptions of healthy food and food safety were investigated. A total perception score was calculated for each participant.

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  • Community pharmacists in the UAE have a significant opportunity to promote the safe use of complementary and alternative medicine (CAM), but their current role is underutilized.
  • A national survey assessed knowledge, attitudes, and practices regarding CAM among 373 pharmacists, revealing that while over 50% understood CAM functions, knowledge of side effects and drug interactions was weaker.
  • Although many pharmacists had positive attitudes towards CAM, 40% viewed it as effective only for minor issues, and only 47% discussed toxic effects, especially those with less experience working in independent pharmacies.
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  • The study focuses on how maternal traits and infant feeding practices affect infant growth during the first 18 months of life.
  • It analyzed data from 256 pregnant women in the UAE, identifying factors like maternal nationality and weight that may lead to infants being overweight.
  • The research suggests that exclusive breastfeeding and timely introduction of solid foods can lower the odds of infants being overweight, indicating a need for programs to educate mothers on effective feeding practices.
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A growing body of evidence suggests that cancer remains a significant global health challenge, necessitating the development of novel therapeutic approaches. In recent years, the molecular crosstalk between polyphenols and gut microbiota has emerged as a promising pathway for cancer prevention. Polyphenols, abundant in many plant-based foods, possess diverse bioactive properties, including antioxidant, anti-inflammatory, and anticancer activities.

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Background: The COVID-19 pandemic precipitated increased workload, stress, and burnout on healthcare providers on the frontlines of the pandemic, dieticians were no exception. Such unprecedented occupational risks and stressors contributed to a higher intention to quit, potentially leading to workforce shortages, and hindering the delivery of quality care, especially for patients with chronic conditions. The aim of this study was to examine the prevalence factors associated with the intention to quit among dieticians in the United Arab Emirates during a public health emergency.

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Purpose: Recent surveys indicate a significant increase in total caffeine intake among schoolchildren. Limited research has been published concerning the total intake of caffeine among schoolchildren in the Middle East and Gulf Cooperation Council (GCC) countries, including the UAE.

Methods: This cross-sectional survey estimated the total caffeine intake from foods and beverages among 10,275 schoolchildren in the UAE.

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Chicken liver is considered a delicacy in the Middle East where pomegranate molass is commonly used as a salad dressing and in marinade recipes. Marinated chicken liver is a common entrée and represents a value-added product compared to the otherwise unmarinated liver which commands a lower price. The aim of this study was to investigate the inhibitory effects of a pomegranate-based marinade alone or following the addition of cinnamaldehyde or β-resorcylic acid on the spoilage microorganisms present in chicken liver during storage for 14 d at 4°C or under mild temperature abuse conditions (10°C).

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Article Synopsis
  • Whole genome sequencing (WGS) is being increasingly used to diagnose rare diseases, but traditional methods often have low diagnostic yields, typically 25-30%.
  • In a study involving 122 rare disease patients and their relatives, a comprehensive bioinformatics approach led to a diagnostic yield of 35%, with 39% solved when including novel gene candidates.
  • The study also identified several novel genes, expanded the phenotypic understanding of existing conditions, and resulted in critical changes to clinical diagnoses and treatments for some patients.
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Background: Consumption of caffeinated energy drinks (CED) has escalated during the last few years, especially among schoolchildren, with evident adverse health sequelae in this critical age group.

Objective: This study examined the prevalence of CED consumption and its associations with sleep, physical and mental health, and dietary and lifestyle habits among schoolchildren in the United Arab Emirates (UAE).

Method: A structured self-administered online questionnaire was developed and disseminated among schoolchildren aged 14-18 years, selected from schools of the seven emirates of the UAE.

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Restaurant menu calorie labeling is regarded as a promising, cost-effective, and innovative method that will have an impact on the food environment, raise awareness among consumers, and aid in global efforts to prevent obesity. This study aimed to assess the public's calorie literacy, dining practices, and perceived effectiveness of restaurant menu labeling implementation in the United Arab Emirates (UAE). A descriptive, web-based cross-sectional study was conducted among 1279 adults in the UAE.

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Background: Type 2 diabetes (T2D) is a chronic lifelong disease that requires long-term prevention and management strategies in a community setting. A health story is a novel technique that may be used as an effective tool for better prevention and management of T2D.

Objective: The main objective of this study is to develop a story to be used as a social health technique based on contemporary scientific knowledge that may be used at a community level for better communication and management of T2D.

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Heterozygous, pathogenic CUX1 variants are associated with global developmental delay or intellectual disability. This study delineates the clinical presentation in an extended cohort and investigates the molecular mechanism underlying the disorder in a Cux1 mouse model. Through international collaboration, we assembled the phenotypic and molecular information for 34 individuals (23 unpublished individuals).

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Article Synopsis
  • - The study focuses on understanding young adults' perspectives on healthy and sustainable diets in the UAE, recognizing their critical role in adopting these dietary choices.
  • - Researchers analyzed a questionnaire completed by 436 University of Sharjah students, assessing their knowledge, attitudes, practices, and willingness to change regarding sustainable diets.
  • - The findings indicate that the questionnaire is a valid and reliable tool for identifying gaps and opportunities to promote sustainable diets among young adults, with promising statistical results supporting its use in future interventions.
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  • A patient from the 100,000 Genomes Project was identified with a complex genetic variant in the KMT2E gene, which causes O'Donnell-Luria-Rodan syndrome.
  • This case adds new information to the list of genetic mutations associated with this syndrome.
  • It emphasizes the need to re-evaluate previously unexplained cases with improved tools for analyzing structural variants and updated genetic testing panels.
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