Simple and rapid microfluidic device for processing raw human semen and separation of motile sperm based on their intrinsic behavior and morphology.

Sperm separation is pivotal in Assisted Reproductive Technology to address male infertility issues such as low sperm concentration or impaired motility. Traditional microfluidic devices, despite their fair success, often fall short due to complex fabrication and use, or lack of direct sample extraction methods. Our research introduces a microfluidic device designed to enhance sperm quality, focusing on improved motility and morphology, while remaining simple to fabricate and use in infertility clinics.