Association Between Parental Social Position and Childhood Overweight: Mediation by Lifestyle and BMI Patterns During Pregnancy.

In high-income countries, children born to parents with low socio-economic position (SEP) or with non-Western ethnicity are disproportionally affected by obesity as early as preschool age. We assessed how much of these associations were mediated by parental lifestyle and BMI patterns during pregnancy. We characterised 5-6 years old children with or without overweight from the French Etude Longitudinale Française depuis l'Enfance (ELFE) (n = 8584) and the Dutch Generation R birth cohorts (n = 6511).

Dietary intake of polyunsaturated fatty acids, their food sources and fertility in females and males: a preconception prospective population-based cohort study.

Background: Seafood, nuts, and seeds are key dietary sources of polyunsaturated fatty acids (PUFAs), which may benefit reproductive health.

Objectives: This study aims to investigate associations of periconception dietary intake of PUFA-rich foods and omega-3 and omega-6 PUFAs with fecundability and subfertility in females and males.

Methods: Among 830 females and 651 males, participating in a population-based prospective cohort study from preconception onwards, we assessed periconception dietary intake at median 12.

Healthy Lifestyle in the First 1000 Days and Overweight and Obesity Throughout Childhood.

Objectives: Investigate associations of different family healthy lifestyle scores (HLS) during the first 1000 days with childhood overweight and obesity (OWOB).

Methods: Cohort-specific analyses were conducted on participants (n = 25 006) from 4 European birth cohorts (The study on the pre- and early postnatal determinants of child health and development [EDEN], Elfe, France; Generation R, the Netherlands; and Lifeways, Ireland). Three composite HLSs were calculated: a maternal pregnancy HLS based on prepregnancy body mass index (BMI) and diet quality, physical activity, smoking status, and alcohol consumption during pregnancy; a parental pregnancy HLS additionally considering paternal BMI and smoking status; and an infancy HLS based on breastfeeding duration, age of solid food introduction, and exposure to passive smoking.

Associations of periconception dietary glycemic index and load with fertility in women and men: a study among couples in the general population.

Background: The dietary glycemic index (GI) and load (GL) reflect carbohydrate quality and quantity, potentially impacting fertility through modulation of insulin sensitivity and generation of oxidative stress. While fertility is influenced by both women and men, reproductive research often emphasizes maternal factors. We first examined periconception dietary intake in both women and male partners, and subsequent associations of dietary GI and GL with fecundability and subfertility.

Associations of childhood BMI, general and visceral fat mass with metabolite profiles at school-age.

Background: Childhood obesity increases metabolic disease risk. Underlying mechanisms remain unknown. We examined associations of body mass index (BMI), total body fat mass, and visceral fat mass with serum metabolites at school-age, and explored whether identified metabolites improved the identification of children at risk of a metabolically unhealthy phenotype.

Impact of parental lifestyle patterns in the preconception and pregnancy periods on childhood obesity.

Introduction: High prevalence of overweight and obesity already observed in preschool children suggests the involvement of early-life risk factors. Preconception period and pregnancy are crucial windows for the implementation of child obesity prevention interventions with parental lifestyle factors as relevant targets. So far, most studies have evaluated their role separately, with only a few having investigated their potential synergistic effect on childhood obesity.