Publications by authors named "Mingxu Yan"
Introduction: Tocilizumab (TCZ) has been demonstrated to be effective in treating thyroid-associated ophthalmopathy (TAO); however, its efficacy in hormone-resistant dysthyroid optic neuropathy (DON) remains unclear. This study aims to identify baseline and post-treatment indicators that can predict the necessity for surgical intervention following TCZ therapy.
Methods: Thirty-one hormone-resistant DON patients treated with TCZ were categorized into surgery (n=15, 7 males, 8 females) and non-surgery (n=16, 8 males, 8 females) groups based on their post-TCZ surgical status.
Chatbot-based multimodal AI holds promise for collecting medical histories and diagnosing ophthalmic diseases using textual and imaging data. This study developed and evaluated the ChatGPT-powered Intelligent Ophthalmic Multimodal Interactive Diagnostic System (IOMIDS) to enable patient self-diagnosis and self-triage. IOMIDS included a text model and three multimodal models (text + slit-lamp, text + smartphone, text + slit-lamp + smartphone).
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- AI technology is advancing rapidly in disease diagnosis, especially in ophthalmology, but traditional image-based methods struggle due to the absence of medical histories.
- The study aims to create a multimodal AI system using ChatGPT alongside anterior segment images to enhance diagnosis and triage of eye diseases, with a focus on high sensitivity and specificity.
- Conducted across three Chinese cities, the research will involve collecting patient histories and images in phases to evaluate the AI's accuracy, using expert panels to set reference standards.