Publications by authors named "Ming-Hui OuYang"
Article Synopsis
- - The study investigates the effects of Columbianadin (CBN), a compound from traditional medicine, on inhibiting osteoclastogenesis, which contributes to bone loss, and seeks to identify its underlying mechanisms.
- - Researchers used transcriptomics, RT-PCR, Western blot analysis, and proteomics to uncover changes in gene expression during osteoclast differentiation, focusing on the S6K/FLNC/ITGβ3 signaling pathway.
- - Results showed that CBN significantly reduced FLNC levels, which in turn decreased markers of osteoclast differentiation and bone resorption in ovariectomized mice, suggesting CBN could be a therapeutic option for bone-related disorders.
Background: Ginseng Radix et Rhizoma (GS) is frequently used as an adjuvant therapy for patients with heart failure (HF). Metoprolol is widely used in patients with HF. However, there is no report on the combined effects of GS and metoprolol in patients with HF.
View Article and Find Full Text PDFEffect of hyperoside on osteoporosis in ovariectomized mice through estrogen receptor α/ITGβ3 signaling pathway.
Eur J Pharmacol
August 2024
Osteoporosis is a highly prevalent bone metabolic disease in menopause due to estrogen deficiency. Hyperoside is a main compound in Semen cuscutae. Our team previously reported that Semen cuscutae has anti osteoporosis effect on ovariectomized mice by inhibiting bone resorption of osteoclasts.
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