Publications by authors named "Maxime Fauter"
Uveitis in Giant Cell Arteritis: A Retrospective Study of Seven Observational Cases and Literature Review.
Ocul Immunol Inflamm
October 2024
Purpose: To describe the demographic and clinical characteristics of uveitis in patients with giant cell arteritis (GCA), their treatments, and evolution.
Methods: A national retrospective cohort study was performed. The inclusion criteria were as follows: patients with GCA fulfilling the 2022 ACR/EULAR criteria and a diagnostic of uveitis attested by an ophthalmologist.
Diagnostic value of elevated serum angiotensin-converting enzyme and lymphopenia in patients with granulomatous hepatitis.
Sarcoidosis Vasc Diffuse Lung Dis
September 2023
Article Synopsis
- - Granulomatous hepatitis (GH) can result from various causes, with sarcoidosis being a key granulomatous disease affecting the liver.
- - This study examined the potential of serum angiotensin converting enzyme (sACE) levels and lymphopenia as diagnostic markers for sarcoidosis in patients with GH by analyzing records from a French hospital.
- - Findings showed that lymphopenia had a high specificity for sarcoidosis diagnosis, especially when paired with elevated sACE levels, and this specificity was particularly high (100%) in patients under 50 years old.
Introduction: Sarcoidosis is a systemic granulomatosis of unknown etiology, characterized by the presence of immune granulomas. Liver damage is a relatively common extra-pulmonary manifestation, occurring in 3.6-30% of cases.
View Article and Find Full Text PDFArticle Synopsis
- Hemophagocytic lymphohistiocytosis (HLH) is a serious syndrome marked by excessive immune activation, and its diagnosis often relies on the HLH-2004 criteria and the Hscore.
- This study introduces a machine learning model designed to identify HLH utilizing a dataset of 207 adult patients, specifically focusing on those with glycosylated ferritin measurements.
- The model achieved a sensitivity of 71.4% and excellent predictive values, but more research with larger, diverse groups is needed to enhance its diagnostic capability.
The significance of extreme hyperferritinemia and its association with certain diagnoses and prognoses are not well characterized. We performed a retrospective analysis of adult patients with at least one total serum ferritin (TSF) measurement ≥ 5000 µg/L over 2 years, in three university hospitals. Conditions associated with hyperferritinemia were collected, and patients were classified into 10 etiological groups.
View Article and Find Full Text PDFBackground And Objective: Familial Mediterranean fever (FMF) is the most frequent hereditary autoinflammatory disease. Its diagnosis relies on a set of clinical criteria and a genetic confirmation on identification of biallelic pathogenic variants. encodes pyrin, an inflammasome sensor.
View Article and Find Full Text PDFLow glycosylated ferritin is a sensitive biomarker of severe COVID-19.
Cell Mol Immunol
November 2020
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December 2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up extraordinary challenges. This unprecedented situation led to the inception of numerous fundamental research protocols and many clinical trials. It quickly became apparent that although COVID-19, in the vast majority of cases, was a benign disease, it could also develop a severe form with sometimes fatal outcomes.
View Article and Find Full Text PDF