Publications by authors named "Matthews B Fish"
Background: Observational data have suggested that patients with moderate to severe ischemia benefit from revascularization. However, this was not confirmed in a large, randomized trial.
Objectives: Using a contemporary, multicenter registry, the authors evaluated differences in the association between quantitative ischemia, revascularization, and outcomes across important subgroups.
Article Synopsis
- The study investigates how the size of the heart affects the accuracy of SPECT myocardial perfusion imaging (MPI) in identifying obstructive coronary artery disease (CAD).
- Among 2066 patients, it was found that those with a low left ventricular volume had lower diagnostic performance compared to those with larger volumes, particularly affecting older and male patients.
- The results indicate that smaller heart sizes lead to a significant decrease in the effectiveness of SPECT MPI, highlighting the need for tailored diagnostic approaches based on cardiac size, age, and sex.
Article Synopsis
- High-speed (HS) single-photon emission computed tomography (SPECT) offers quick imaging of heart perfusion that is comparable to conventional SPECT methods, suggesting it could be a reliable alternative for diagnosing cardiac issues.
- In a study involving 50 patients, both HS and conventional SPECT were tested against coronary angiography, demonstrating HS SPECT's higher sensitivity and accuracy in detecting perfusion abnormalities.
- Results indicated a significant correlation between HS SPECT scores and coronary stenosis severity, implying that HS SPECT can efficiently identify heart conditions, making it beneficial for clinical use.
Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging.
Gary V Heller
,
Timothy M Bateman
,
Lynne L Johnson
,
S James Cullom
,
James A Case
,
Matthews B Fish
J Nucl Cardiol
September 2004
Article Synopsis
- Attenuation artifact can complicate the interpretation of nuclear cardiology images, leading to inefficiencies and the frequent need to compare stress and rest image sets.
- A study involving ten nuclear cardiologists found that while standard stress imaging showed limited clarity (only 37% classified as definitely normal or abnormal), adding attenuation correction improved clarity to 84% and reduced the perceived need for additional rest imaging from 77% to 43%.
- The results suggest that using attenuation correction in stress-only imaging enhances diagnostic accuracy and lab efficiency, benefiting the interpretation process.