Publications by authors named "Mathilde Roussel"
BACKGROUNDIn France, cervical cancer screening for females aged 30--65 years primarily tests for high-risk (HR) human papillomavirus (HPV) infections.AIMWe aimed to map the prevalence of cervical infections caused by HPV16 and/or 18, or by any of 12 other carcinogenic HPV genotypes and compare prevalence estimates from tests from spontaneous medical visits (opportunistic screening) or the national screening programme (organised screening).METHODSWe extracted data from a large network of biology laboratories, containing all available results from HR HPV tests performed between 1 January 2020 and 30 November 2023 in metropolitan France.
View Article and Find Full Text PDF[“Junior Doctors” in Nephrology in France: first feedback].
Nephrol Ther
August 2024
Medical education in France has undergone several major reforms in recent years. In 2017, the reform of the third cycle of medical studies was implemented. This particularly affected nephrology.
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- Evaluating glomerular filtration rate (GFR) in children is tough, prompting the development of new estimation formulas which were tested in a pediatric population at a nephrology center.
- In a study of 307 patients deemed at "kidney risk," both creatinine-based and cystatin C-based formulas were used to assess GFR against measued values, revealing that creatinine-based formulas often overestimate GFR across various age groups.
- Ultimately, the study found that cystatin C-based equations and combined formulas performed significantly better in providing accurate GFR estimations, particularly in patients with higher measured GFR values.
Is shrunken pore syndrome also a reality in children?
J Intern Med
February 2024
Article Synopsis
- Shrunken pore syndrome (SPS) in children is determined by specific eGFR ratios and is linked to higher cardiovascular risk, though prior studies haven't shown this connection to increased morbidity and mortality.
- The study examined 307 pediatric patients at renal risk, using various formulas to assess SPS prevalence and its correlation with cardiovascular health.
- Findings indicated that SPS prevalence varies significantly based on the methods used; children with SPS had higher levels of C-reactive protein and phosphate, along with smaller body size, signaling potential long-term cardiovascular issues that warrant further investigation.
Rapid investigation of BA.4/BA.5 cases in France.
Front Public Health
November 2022
Aim: We aimed to describe the characteristics of individuals infected by BA.4 or BA.5 in France in comparison to BA.
View Article and Find Full Text PDFWe analyzed 324,734 SARS-CoV-2 variant screening tests from France enriched with 16,973 whole-genome sequences sampled during September 1, 2021-February 28, 2022. Results showed the estimated growth advantage of the Omicron variant over the Delta variant to be 105% (95% CI 96%-114%) and that of the BA.2 lineage over the BA.
View Article and Find Full Text PDFBackground: Achromobacter are emerging pathogens in cystic fibrosis patients. Mechanisms of resistance to fluoroquinolones are unknown in clinical isolates. Among non-fermenting Gram-negative bacilli, fluoroquinolone resistance is mostly due to amino acid substitutions in localized regions of the targets (GyrA, GyrB, ParC and ParE) named QRDRs, but also to efflux.
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