Adipose tissue and androgens: the ins and outs.

Adipose tissue (AT), one of the largest endocrine tissues in the human body, is an important site for the storage and production of steroid hormones. In particular, AT's capacity to produce androgens could enable it to have a regulatory role in local or general hormone homoeostasis. The links between obesity, polycystic ovary syndrome (PCOS), metabolic disorders, and hormonal balance emphasise the importance of understanding the intricate relationships between AT and androgen dynamics within AT.

Specificities of mammary and periprostatic adipose tissues: A perspective from cancer research.

In addition to the major subcutaneous and visceral adipose tissues (AT), other adipose depots are dispersed throughout the body and are found in close interaction with proximal organs such as mammary and periprostatic AT (MAT and PPAT respectively). These ATs have an effect on proximal organ function during physiological processes and diseases such as cancer. We highlighted here some of their most distinctive features in terms of tissular organization and responses to external stimuli and discussed how obesity affects them based on our current knowledge.