Racial disparities and outcomes in neonatal hypoxic-ischemic encephalopathy.

Objectives: To investigate racial disparities in the prevalence, severity, intervention, and outcomes of hypoxic-ischemic encephalopathy (HIE) among neonates in the United States.

Study Design: We analyzed data from the National Inpatient Sample (NIS) dataset, including full-term infants diagnosed with HIE from 2010 to 2018. Regression analysis was performed to control for clinical and demographic variables.

Mode of Delivery and Neonatal Transition: Insights from Electrical Cardiometry.

Background/objectives: Examining hemodynamic changes during the early transition period aids in identifying variations in neonatal outcomes linked to ante- or intrapartum events. It facilitates the recognition of potential impacts stemming from common intrapartum management practices. The current literature provides scant insights into cardio-circulatory changes during the crucial first 10 min after birth.

Exhaled Breath Volatile Organic Compounds in Pregnancy: A Pilot Study.

This study aimed to assess the volatile organic compounds (VOC)s in breath samples collected noninvasively from pregnant women during pregnancy and postpartum and compare it with nonpregnant controls.This pilot study included 50 subjects: 10 pregnant patients in their first trimester, 10 in second trimester, 10 in third trimester, 10 in the first postpartum week, and 10 nonpregnant subjects as a control. We collected exhaled breath from subjects who reported to be healthy and free of any respiratory symptoms.

Volatile organic compounds in exhaled breath of newborns: a pilot study.

Objective: To assess volatile organic compounds (VOCs) in breath samples collected non-invasively from preterm and full-term infants.

Methods: This was a pilot study included preterm and full-term infants who were not intubated or suspected or diagnosed with metabolic or gastrointestinal disorders. The samples were analyzed for VOCs using a selected-ion flow-tube mass spectrometer.

Prevalence and Outcomes of Gastrointestinal Anomalies in Down Syndrome.

Objectives:  Our objective was to investigate the prevalence of small intestinal atresia and Hirschsprung's disease (HD) in infants with Down syndrome (DS) and its impact on outcomes.

Study Design:  We analyzed the National Inpatient Sample dataset. We included infants with DS, small intestinal atresia, HD, and the concomitant occurrence of both conditions.

Acute kidney injury in infants with hypoxic-ischemic encephalopathy.

Background: This study aimed to investigate the prevalence of acute kidney injury (AKI) in infants with varying degrees of hypoxic-ischemic encephalopathy (HIE) and its associated outcomes, including mortality and length of stay (LOS).

Methods: The study used the National Inpatient Sample (NIS) dataset from 2010 to 2018. Regression analysis was used to control confounding variables.

Acute kidney injury in infants diagnosed with congenital diaphragmatic hernia.

Background: To assess the association and outcomes of acute kidney injury (AKI) in infants diagnosed with congenital diaphragmatic hernia (CDH).

Methods: We analyzed the National Inpatient Sample dataset for the years 2010 through 2018. We evaluated the prevalence and outcomes associated with AKI in infants diagnosed with CDH.

Kidney replacement therapy in neonates: utilization trends and outcomes.

Background: We aimed to assess prevalence and clinical characteristics of newborns receiving kidney replacement therapy (KRT).

Methods: We used the National Inpatient Sample (NIS) dataset for the years 2000-2017. Newborns treated with peritoneal dialysis (PD), hemodialysis (HD), and continuous KRT (CKRT) were included.

A Randomized Controlled Trial of a 30- versus a 120-Second Delay in Cord Clamping after Term Birth.

Objective: Delayed cord clamping (DCC) has been recently adopted in neonatal resuscitation. The immediate cardiac hemodynamic effects related to DCC more than 30 seconds was not studied. We aimed to study the effect of DCC at 120 seconds compared with 30 seconds on multiple hemodynamic variables in full-term infants using an electrical cardiometry (EC) device.

Disparities in tracheostomies and gastrostomy tubes in infants at the edge of viability.

Objectives: To assess trends of clinical practice of tracheostomy and gastrostomy tube (G-tube) placement over a 25-year period and to assess the association of both procedures with outcomes in extremely low birth weight (ELBW) infants (<1000 g).

Methods: We reviewed and analyzed data obtained from the National Inpatient Sample dataset from 1993 to 2018. ELBW infants who received a tracheostomy and or G-tube were included.

Urinary N-terminal Pro-Brain Natriuretic Peptide in Newborn Infants with Cardiac and Pulmonary Diseases.

Objectives: The aim of this study was to assess the feasibility of urinary N-terminal pro-brain natriuretic peptide (NT-proBNP) as noninvasive screening tool for congenital heart diseases in full-term neonates with respiratory distress.

Study Design: A prospective cohort study was conducted on 90 full-term infants. Newborn were assigned into three groups: pulmonary, cardiac, and control groups.

Neonatal stroke: Clinical characteristics and neurodevelopmental outcomes.

Background: Neonatal stroke can potentially result in significant neurological sequelae in affected infants. Studies on neurodevelopmental outcomes and the need for rehabilitation therapies in the first two years are limited. We aimed to describe the clinical characteristics, diagnostic evaluation, and neurodevelopmental outcomes of a cohort of infants with neonatal stroke.

The incidence of pericardial effusion requiring intervention in infants with a history of umbilical catheter placement: the US national database.

Objectives: To assess the association of umbilical catheters (UC) placement with pericardial effusion (PCE) in newborn infants.

Study Design: We analyzed the National Inpatient Sample dataset. We compared prevalence of PCE in infants with UC versus those without in three subpopulations: infants with birth weight (BW) > 2500 g or GA > 34 weeks, preterm infants with BW < 1500 g, and term infants with congenital heart disease (CHD) using regression analysis methods while controlling for clinical and demographic variables.

Platelet Transfusion and Outcomes of Preterm Infants: A Cross-Sectional Study.

Background: Prophylactic platelet transfusion has been adopted as a ubiquitous practice in management of thrombocytopenia in preterm infants to reduce the risk of bleeding.

Objectives: The objectives of this study were to report the prevalence of platelet transfusion among preterm infants with thrombocytopenia and to assess the association of platelet transfusion with mortality and morbidity in this population.

Methods: A cross-sectional study that utilized National Inpatient Sample for the years 2000-2017 was conducted.

Superior Mesenteric Artery Blood Flow in Parenterally Fed Versus Enterally Fed Preterm Infants.

Objectives: The aim of the study was to compare superior mesenteric artery (SMA) flow in premature infants with parenteral and enteral nutrition.

Methods: A prospective study was conducted on 2 groups of preterm infants with gestational age of 280/7 to 366/7 weeks: group 1 did not qualify for early enteral feeds and received parenteral nutrition (PN), and group 2 received early enteral feeding. SMA peak systolic velocity (PSV), end diastolic velocity (EDV), and pulsatility index (PI) were measured using Doppler ultrasound before starting feeds at day 1 and at day 5.

Spontaneous intestinal perforation in premature infants: a national study.

Objectives: To assess the prevalence and outcomes of spontaneous intestinal perforation (SIP) in very low birth weight infants.

Study Design: This cross-sectional study utilized the National Inpatient Sample dataset for the years 2002-2017. All premature infants with birth weight (BW) <1500 g and with gestational age (GA) ≤32 weeks were included.

Trends and racial disparities for acute kidney injury in premature infants: the US national database.

Background: To assess prevalence and outcomes of acute kidney injury (AKI) in very-low-birth-weight infants.

Methods: This cross-sectional study utilized the National Inpatient Sample (NIS) dataset for years 2000-2017. All premature infants with birth weight (BW) <1500g and/or gestational age (GA) ≤32 weeks were included.

Esophageal perforation in very low birth weight infants.

We aimed to assess the prevalence and outcomes of esophageal perforation in very low birth weight infants. This retrospective cohort study utilized the US National Inpatient Sample dataset for the years 2000 to 2017. A total of 1,755,418 very low birth weight infants were included; of them, 861 (0.