New methods, old questions: advancing the study of unconscious perception.

Since the early experimental studies of the late 19th century, research on unconscious perception has been shaped by persistent methodological challenges and evolving experimental approaches aimed at demonstrating perception without awareness. In this review, we will discuss some of the most relevant challenges researchers have faced in demonstrating unconscious perception, and examine how different measures of awareness (e.g.

Spatio-temporal activity of brain electrical sources during processing of abstract social concepts.

concepts frequently refer to socialness, that is knowledge about interactions between people. Grounded cognition theories propose that such social concepts are represented in brain circuits involved in processing social interactions. The present event-related potential study investigated the time course of electrical brain activity in response to abstract social concepts compared to abstract control concepts presented during a lexical decision task.

Left inferior parietal lobe and auditory cortex jointly contribute to sound knowledge retrieval.

Background: Conceptual knowledge is central to human cognition. Neuroimaging studies suggest that conceptual processing relies on the joint contribution of modality-specific perceptual-motor and multimodal brain regions. In particular, the multimodal left inferior parietal lobe (IPL) couples with auditory association cortex during sound knowledge retrieval and with somatomotor cortex during action feature retrieval.

Association of the Biopsychosocial Factors Adverse Childhood Experiences, Adult Attachment Style, Emotion Regulation, and Mitochondrial Density in Immune Cells with Major Depressive Disorder.

Introduction: Major depressive disorder (MDD) is one of the most prevalent mental disorders associated with various negative impacts such as lower overall quality of life, increased morbidity risk, and even premature mortality. According to the biopsychosocial model of health and disease, multiple factors contribute to the development and manifestation of MDD. Here, we assessed preselected social, psychological, and biological variables and tested their power to predict MDD diagnosis using logistic regression models.

Task set reconfiguration following masked and unmasked task cues.

Numerous previous studies have shown that masked stimuli trigger cognitive control processes, including the activation of task sets, and thereby affect subsequent processing. However, it has not been directly tested whether unconsciously activated task sets also need to be reconfigured when switching to a new task, as has been shown for consciously triggered task sets. To test whether unconsciously activated task sets are subject to inhibitory processes, we measured n-2 repetition costs following masked cue presentation in a task switching design.

Does affective processing require awareness? On the use of the Perceptual Awareness Scale in response priming research.

Masked priming paradigms are frequently used to shine light on the processes of nonconscious cognition. Introducing a new method to this field, Lähteenmäki et al. (2015) claimed that affective priming requires awareness.

Inhibition of cued but not executed task sets depends on cue-task compatibility and practice.

In task switching, processing a task cue is thought to activate the corresponding task representation ("task set"), thereby allowing for advance task preparation. However, the contribution of preparatory processes to the emergence of n-2 repetition costs as index of task set inhibition processes is debated. The present study investigated whether merely preparing for a task activates a corresponding task set, which needs to be inhibited in order to switch to a different task.

The Relation Between Subjective and Objective Measures of Visual Awareness: Current Evidence, Attempt of a Synthesis and Future Research Directions.

Within the realm of consciousness research, different methods of measuring the content of visual awareness are used: On the one hand, subjective measures require a report of sensory experiences related to a stimulus. On the other hand, objective measures rely on the observer's performance to accurately detect or discriminate the stimulus. The most appropriate measure of awareness is currently debated.

Group differences in OXT methylation between patients with Major Depressive Disorder and healthy controls: A pre-registered replication study.

Depression is linked to stress which leaves traces in the epigenetic signature of genes. The oxytocin system is implicated in allostatic processes promoting adaption to environmental stressors. Interactions of the oxytocin system with the environment, e.

Dynamics of task preparation processes revealed by effect course analysis on response times and error rates.

Cuing or executing a task impacts processing pathways for task-relevant information. While there is ample evidence that processing associated with task execution changes with practice, such evidence regarding cue-induced task preparation is scarce. Here we explored practice-related changes of processing pathways by task cuing in order to assess the plasticity of task preparation.

Experiential grounding of abstract concepts: Processing of abstract mental state concepts engages brain regions involved in mentalizing, automatic speech, and lip movements.

concepts like mental state concepts lack a physical referent, which can be directly perceived. Classical theories therefore claim that abstract concepts require amodal representations detached from experiential brain systems. However, grounded cognition approaches suggest an involvement of modal experiential brain regions in the processing of abstract concepts.

Subjective and objective measures of visual awareness converge.

Within consciousness research, the most appropriate assessment of visual awareness is matter of a controversial debate: Subjective measures rely on introspections of the observer related to perceptual experiences, whereas objective measures are based on performance of the observer to accurately detect or discriminate the stimulus in question across a series of trials. In the present study, we compared subjective and objective awareness measurements across different stimulus feature and contrast levels using a temporal two-alternative forced choice task. This task has the advantage to provide an objective psychophysical performance measurement, while minimizing biases from unconscious processing.

Conceptual representations in the default, control and attention networks are task-dependent and cross-modal.

Conceptual knowledge is central to human cognition. Neuroimaging studies suggest that conceptual processing involves modality-specific and multimodal brain regions in a task-dependent fashion. However, it remains unclear (1) to what extent conceptual feature representations are also modulated by the task, (2) whether conceptual representations in multimodal regions are indeed cross-modal, and (3) how the conceptual system relates to the large-scale functional brain networks.

Association between parental separation, childhood trauma, neuroticism, and depression: a case control study.

Background: Parental separation has been suggested to be associated with depression development in offspring. The new family constellation subsequent to separation could be associated with elevated scores of childhood trauma, shaping more emotionally instable personalities. This could ultimately be a risk factor for mood disorders and particularly the development of depression in life.

Electrophysiological correlates of response time outliers: Outlier related potentials.

In response time (RT) research, RTs which largely deviate from the RT distribution are considered "outliers". Outliers are typically excluded from RT analysis building upon the implicit assumption that cognitive processing is distorted in outlier trials. The present study aims to test this assumption by comparing cognitive processing indexed by event-related potentials (ERP) of trials with outliers and valid trials in two different tasks.

Assessing subjective prime awareness on a trial-by-trial basis interferes with masked semantic priming effects.

Ratings of perceptual experience on a trial-by-trial basis are increasingly used in masked priming studies to assess prime awareness. It is argued that such subjective ratings more adequately capture the content of phenomenal consciousness compared to the standard objective psychophysical measures obtained in a session after the priming experiment. However, the concurrent implementation of the ratings within the priming experiment might alter magnitude and processes underlying semantic priming, because participants try to identify the masked prime.

Factors related to the development of executive functions: A cumulative dopamine genetic score and environmental factors predict performance of kindergarten children in a go/nogo task.

Background: This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.

Methods: Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity.

The relationship between parenting behavior and the personality of kindergarten children.

According to Cloninger's biosocial model of personality touching upon temperament and character, personality development is a lifelong adaptive process that begins in early childhood. Similarly, theories of parenting behavior and attachment predict that associations between personality and parenting behavior should be found in young children. The present study therefore had the goal to investigate, whether associations between parenting behavior and personality in terms of Cloninger's temperament and character dimensions previously found in adolescence and adults can already be observed in kindergarten children.

Academic training increases grounding of scientific concepts in experiential brain systems.

Scientific concepts typically transcendent our sensory experiences. Traditional approaches to science education therefore assume a shift towards amodal or verbal knowledge representations during academic training. Grounded cognition approaches, in contrast, predict a maintenance of grounding of the concepts in experiential brain networks or even an increase.

Task cue influences on lexical decision performance and masked semantic priming effects: The role of cue-task compatibility.

Recent research demonstrated that mere presentation of a task cue influences subsequent unconscious semantic priming by attentional sensitization of related processing pathways. The direction of this influence depended on task-set dominance. Dominant task sets with a compatible cue-task mapping were supposed to be rapidly suppressed, while weak task sets showed more sustainable activation.

Cumulative Genetic Score of DRD2 Polymorphisms Is Associated with Impulsivity and Masked Semantic Priming.

Individual differences in the magnitude of semantic priming effects are associated with executive functions (EF). Striatal dopamine has been shown to be associated with EF as well as impulsivity and could therefore be associated with differences in the magnitude of semantic priming. We investigated n = 155 individuals in an unmasked as well as in a masked semantic priming paradigm.

Differential temporo-spatial pattern of electrical brain activity during the processing of abstract concepts related to mental states and verbal associations.

Refined grounded cognition accounts propose that abstract concepts might be grounded in brain circuits involved in mentalizing. In the present event-related potential (ERP) study, we compared the time course of neural processing in response to semantically predefined abstract mental states and verbal association concepts during a lexical decision task. In addition to scalp ERPs, source estimates of underlying volume brain activity were determined to reveal spatio-temporal clusters of greater electrical brain activity to abstract mental state vs.

Primary emotions as predictors for fear of COVID-19 in former inpatients with Major Depressive Disorder and healthy control participants.

Introduction: There are reports of an increase in depressive symptoms and fear during the COVID-19 pandemic, in particular in patients with depression. This study investigates factors related to fear of COVID-19 in former inpatients suffering from depression and healthy controls by assessing variables typically associated with depression and anxiety disorders, i.e.