Berries from Ruiz & Pav.: A Southern Chile Climbing Shrub as a Source of Antioxidants Against Chronic Diseases.

In recent years, numerous studies have emerged on the biological activities of endemic berries from the Valdivian Forest and their potential for therapeutic use. However, some species appear to have been relatively neglected. The objective of this study was to conduct, for the first time, a phytochemical composition analysis of a hydroalcoholic extract of Ruiz & Pav.

Biological potential of fern extract: integration of UHPLC/ESI/QToF/MS analysis, antioxidant activity, molecular docking and molecular dynamics simulation.

(J.F.Gmel.

Green Extract from Pre-Harvest Tobacco Waste as a Non-Conventional Source of Anti-Aging Ingredients for Cosmetic Applications.

The cigarette production from generates significant amounts of waste, with an estimated 68.31 million tons of pre- and post-harvest waste discarded annually. The pre-harvest waste includes the upper parts of the plant, inflorescences, and bracts, which are removed to help the growth of the lower leaves.

Influence of an Antioxidant Nanomaterial on Oral Tablet Formulation: Flow Properties and Critical Quality Attributes.

Antioxidant nanomaterials, particularly mesoporous silica nanoparticles (MSNs) functionalized with polyphenols, offer innovative solutions for protecting oxidation-sensitive components and enhancing bioavailability in pharmaceuticals or extending the shelf life of nutraceutical and food products. This study investigates the influence of MSNs functionalized with caffeic acid (MSN-CAF) on powder flow properties and their tableting performance. Aminated MSNs were synthesized via co-condensation and conjugated with caffeic acid using EDC/NHS chemistry.

Nutritional, Phytochemical, and Biological Characterization of Peel, Pulp, and Seed Powder from the Fruits of and : Potential as a Functional Ingredient.

Job. (common name "mikuna") and O.R.

Antioxidant and Antidiabetic Potential of the Antarctic Lichen Ethanolic Extract: Metabolomic Profile and In Vitro and In Silico Evaluation.

Lichens are an important source of diverse and unique secondary metabolites with recognized biological activities through experimental and computational procedures. The objective of this study is to investigate the metabolomic profile of the ethanolic extract of the Antarctic lichen and evaluate its antioxidant and antidiabetic activities with in vitro, in silico, and molecular dynamics simulations. Twenty-one compounds were tentatively identified for the first time using UHPLC/ESI/QToF/MS in negative mode.

Metabolomic Profiling and Antioxidant Properties of Chilean Cav.: Insights from Leaves, Flowers, and Monofloral Honey.

This study aimed to characterize the metabolomic profile of monofloral honey from (ulmo) and evaluate the potential transfer of bioactive compounds from the plant parts, including the leaves and flowers, to the honey. Using UHPLC/Q-TOF-MS analysis, various flavonoids and phenolic acids were identified and quantified in extracts from the leaves, flowers, and honey from . Given their rich polyphenolic composition, leaves were included in this study to assess their potential contribution to the antioxidant properties and chemical markers of ulmo honey.

Untargeted Chemical Profile, Antioxidant, and Enzyme Inhibition Activity of L. from the Peruvian Amazon: A Contribution to the Validation of Its Pharmacological Potential.

is a plant of great value in traditional medicine known for its content of bioactive compounds, such as physalins and withanolides, which possess diverse biological activities. In this study, the chemical profile, antioxidant activity, and enzyme inhibition capacity of aqueous and ethanolic extracts obtained from the root, stem, leaves, calyx, and fruits of collected in Peru were evaluated. A total of forty-two compounds were detected in the extracts using UHPLC-ESI-QTOF-MS analysis.

Extraction of Bioactive Compounds from Cav. Using Natural Deep Eutectic Solvents: A Contribution to the Plant Green Extract Validation of Its Pharmacological Potential.

A sustainable alternative to replace the use of toxic and non-biodegradable conventional solvents for the extraction of active principles from plants is natural deep eutectic solvents (NADESs). Cav. (Zygophyllaceae) is a plant widely distributed in semiarid areas of western Argentina.

Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials.

In recent years, numerous studies have emerged on the biological activities of bryophytes and their potential for therapeutic use. However, mosses appear to be a relatively overlooked group. The objective of this study was to conduct a phytochemical analysis of one hydroalcoholic extract of and to evaluate its potential as an antioxidant and antimicrobial agent.

Biological activities of lichen extracts and UHPLC-ESI-QTOF-MS analysis of their secondary metabolites.

This research was designed to investigate the metabolite profiling, phenolics content, and the trypanocidal, nematicidal, antibacterial, antifungal, and free radical scavenging properties of Motyka. The air-dried material was extracted successively with dichloromethane and methanol (UlMeOH). Two phases were obtained from the extract with dichloromethane, one soluble in methanol (UlDCM-s) and the other insoluble (UlDCM-i).

Epibiotic bacterial community composition varies during different developmental stages of Octopus mimus: Study of cultivable representatives and their secondary metabolite production.

Marine microbial communities colonizing the skin of invertebrates constitute the primary barrier between host and environment, potentially exerting beneficial, neutral, or detrimental effects on host fitness. To evaluate the potential contribution of epibiotic bacteria to the survival of early developmental stages of Octopus mimus, bacterial isolates were obtained from eggs, paralarvae, and adults. Their enzymatic activities were determined, and antibacterial properties were assessed against common marine pathogens.

Gillies ex Hooker et Arnott (Oxalidaceae): Chemical Analysis, Biological In Vitro and In Vivo Properties and Behavioral Effects.

In this work, a decoction (DOe) and a methanolic global extract (MGEOe), obtained with the aerial parts of Gillies ex Hooker et Arnott (Oxalidaceae), were evaluated. The high-resolution liquid chromatography in conjunction with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QTOF-MS) analysis showed forty compounds in MGEOe and twenty-nine in DOe, including flavones, C-glycosyl flavones, isoflavones, fatty acids, terpenes, phenolic acids, and sterols. The antioxidant properties were evaluated by DPPH, TEAC, FRAP, and ILP assays.

Phytochemical profiling, antioxidant, enzymatic inhibitory, and antibacterial activities of .

, a member of the Namaceae family, is a source of metabolites and has been traditionally used as an anti-inflammatory. This work aimed to determine the total phenolic content (TPC), total flavonoid content (TFC), antioxidant effect, inhibition of α-glucosidase and cholinesterase enzymes (AChE, BChE), and antibacterial activity of the methanolic extract (ME) and subfractions of . The findings revealed that ME and its subfractions exhibited significant antioxidant capacity, with the ethyl acetate fraction being the most active, displaying an IC of 17.

In Vitro Inhibition of Enzymes and Antioxidant and Chemical Fingerprinting Characteristics of Ruiz & Pav. Fruits, an Endemic Plant of the Valdivian Forest of Chile.

The World Health Organization has emphasized the importance of consuming small fruits for the prevention of chronic health problems, including diabetes, cardiovascular diseases, cancer, and obesity, which are named chronic non-communicable diseases (NCDs). Ruiz & Pav., commonly called "aroma de Castilla", is a shrub endemic to Chile from the Salicaceae family that produces an underutilized blue-grey berry that grows wild in southern Chile.

A U.S. Pharmacopeia (USP) overview of Pan American botanicals used in dietary supplements and herbal medicines.

The United States Pharmacopeial Convention (USP) is a nonprofit, scientific, standard-setting organization, and world leader in establishing quality, purity, and testing standards for medicines, foods, and dietary supplements. USP quality standards are used in more than 140 countries and are legally recognized by more than 40 countries. Currently, there is renewed interest in herbal medicines globally, and health policies are being implemented worldwide for the use of complementary and traditional medicine.

Comprehensive Phytochemical Profile of Leaves, Stems and Fruits from Orthopterygium huaucui (A. Gray) Hemsl. and their Antioxidant Activities.

Orthopterygium huaucui, commonly known as "Pate", is a medicinal shrub belonging to the Anacardiaceae family used locally to treat burns and stomach pains. Endemic to Peru, chemical studies on O. huaucui are limited.

Green Separation by Using Nanofiltration of Fruits and Identification of Its Bioactive Molecules through MS/MS Spectrometry.

Membrane technology allows the separation of active compounds, providing an alternative to conventional methods such as column chromatography, liquid-liquid extraction, and solid-liquid extraction. The nanofiltration of a Muérdago ( Mart.) fruit juice was realized to recover valuable metabolites using three different membranes (DL, NFW, and NDX (molecular weight cut-offs (MWCOs): 150~300, 300~500, and 500~700 Da, respectively)).

Chemical composition and antioxidant, enzyme inhibition and cytoprotective activity of two Antarctic lichens of the genus (Pannariaceae).

Lichens contain different types of chemical compounds with multiple biological activities that demonstrate their potential pharmacological use. This research aims to report the metabolomic identification of the ethanolic extracts of and , their antioxidant, enzyme inhibitory, and their cytoprotection activity. Sixteen metabolites were identified in and twelve in ; the extracts reported variable antioxidant activity with IC >350 µg/mL in DPPH·, values >18 µmol Trolox/g in ORAC and >40 µmol Trolox/g in FRAP and a phenolic compound content >10 mg GAE/g, as well as significant results in cholinesterases, α-glucosidase, pancreatic lipase, α-amylase, and tyrosinase enzyme inhibition activities with IC ranging from 18 to 510 µg/mL, and which were complemented by molecular docking experiments.

Effect of In Vitro Micropropagation on the Chemical, Antioxidant, and Biological Characteristics of Sch. Bip., an Endemic Plant of the Atacama Desert Andean Region.

The species Sch. Bip., commonly called "chachacoma", is widely used as a medicinal plant by the Andean communities of Northern Chile.

Chemical Characterization of Phoenix dactylifera L. Seeds and their Beneficial Effects on the Vascular Response in Hypertensive Rats.

Although Phoenix dactylifera dates are traditionally consumed for their health benefits, no research has been done on the vascular response in hypertensive animals. This study evaluated the vascular relaxation of hydroalcoholic extracts from seeds of three varieties of P. dactylifera; Sukkari seed (SS), Ajwa seed (AS), and Mabroom seed (MS) on L-NAME-induced hypertension and spontaneously hypertensive rats (SHR).

The Potential of Using Cochayuyo () Extract Obtained by Ultrasound-Assisted Extraction to Fight against Aging-Related Diseases.

The world's population is in a demographical transition, with an increase in the number of older adults and prevalence of diseases related to aging. This study evaluated in vitro the potential of using extract (extracted using ultrasound-assisted extraction) to inhibit key enzymes associated with the development of age-related diseases. Our results show that an extract extracted via ultrasound-assisted extracted, as well as an extract conventional extracted from presented antidiabetes potential by exhibiting inhibitory activity against α-glucosidase (91.

Ultra-High-Resolution Liquid Chromatography Coupled with Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry Analysis of (Hook. & Arn.) DC. (Asteraceae) and Antioxidant and Hypocholesterolemic Properties.

Recently, we reported the chemical profile and the hypocholesterolemic effects of a decoction of (Hook. & Arn.) DC.