Determining the need for stabilising therapy of cervical spine injuries on CT: towards standardising decision-making in the emergency department.

Background: In clinical practice, currently no standardised approach exists to determine which patients with cervical spine injury (CSI) on CT scan should receive continued cervical spine immobilisation and a neurosurgeon is generally consulted. Insights into the contribution of CT assessment and classification of CSI in determining the need for stabilising therapy could aid in standardising clinical practice in the emergency department. Standardising clinical practice for cervical spine immobilisation could potentially improve the patient flow in the emergency department by reducing delay in decision-making, particularly in hospitals without availability of immediate neurosurgical consultation.

Diffusion tensor imaging has prognostic value on return to play in hamstring injuries: A prospective cohort study.

Background: Predicting an accurate return to play (RTP) time after hamstring injury remains difficult. The ability of diffusion tensor imaging (DTI) to detect muscle micro-trauma may help to overcome this limitation.

Purpose: To investigate the predictive value of DTI-derived parameters for RTP prognosis following hamstring injury.

The new frontier of MRI: virtual dissection with 3D-PDw sequence. A pilot study on ATiFL anatomy.

Purpose: There is much conflicting data regarding the anatomy of the anterior tibiofibular ligament (ATiFL), even in studies with anatomical specimens. Therefore, this study aims to reassess the anatomy of this ligament using a high-resolution isotropic 3D-PDw MRI sequence.

Methods: From February to May 2024, 72 MRI scans (3 T) of the ankle were performed at Amsterdam UMC.

The effect of CT scanning and metal artefact reduction strategies on measuring knee implant displacement: iMAR - helpful or harmful?

Background: A recent development in diagnosing total knee arthroplasty (TKA) tibial component loosening uses Computed Tomography (CT) images of loaded knees to assess implant micro-motion, but metal artefacts can affect reliability. This study investigates the impact of increased exposure and tube voltage, iterative metal artefact reduction reconstruction (iMAR), Sn-filtering and an extended CT scale (ECTS), compared to a standard knee CT protocol on load-induced implant displacement measurement.

Method: CT scans of a fresh frozen cadaver leg with a TKA were acquired using a standard protocol and four metal artefact reduction strategies: Increased exposure/tube voltage, iMAR, Sn-filtering, and ECTS reconstruction.

Operator variation in applying a knee loading device for evaluation of tibial component loosening in total knee arthroplasty.

Background: A CT-based method has been developed to aid diagnosis of aseptic loosening of the tibial component by scanning the knee in a loading device, and subsequent 3D-image analysis to quantify component displacement. This study evaluated the effect of operator differences in applying the loading device on the component displacement variables, using two image analysis protocols.

Methods: Sixteen subjects underwent repeated CT examinations with valgus and varus loading.

Divergent gene signatures and neutrophil enrichment in lymph nodes of inflammatory arthritis patients.

Background: Lymph node (LN) studies in anti-cyclic citrullinated protein antibodies (ACPA) positive rheumatoid arthritis (RA) patients have revealed notable alterations in adaptive immune cell populations. However, it remains unclear whether similar changes occur in seronegative inflammatory arthritis, such as psoriatic arthritis (PsA) or ACPA-negative RA. This study investigates molecular and cellular alterations in LN biopsies from ACPA-positive RA patients, ACPA-negative inflammatory arthritis (IA) patients, and healthy controls (HCs).

High-Resolution 3D Turbo Spin-Echo Wrist MRI at 7T Accelerated by Compressed Sensing.

This study aimed to obtain high-resolution 3D isotropic turbo spin-echo (TSE) wrist MRI acquisitions at 7T, with and without fat suppression, facilitated by compressed-sensing (CS) acceleration. In 16 healthy subjects, fat-suppressed (FS) and nonfat-suppressed (NFS) TSE wrist images were obtained. The protocol consisted of a SENSE-accelerated scan, with an isotropic voxel size of 0.

A pre-clinical evaluation of geometrical stitching errors in a cone beam system: possible implications for weight-bearing CT imaging of the spine.

BackgroundTotal body cone-beam computed tomography (CBCT) is recently developed for both weight-bearing and non-weight-bearing CT imaging of the spine. Before whole-spine weight-bearing CT is used in clinical practice, potential errors must be addressed, such as the need to stitch multiple volumes due to the field-of-view limitations of CBCT technology.PurposeTo determine the geometric error of fused CBCT images of the spine using automatic stitching software.

Successful rapid return to performance following non-operative treatment of proximal hamstring tendon avulsion in elite athletes.

Objectives: Proximal hamstring tendon avulsion injuries are severe and potentially career-threatening for elite athletes. Until now, no data have been published on the non-operative treatment of this injury in elite athletes. Therefore, the objective of this case series was to describe return to performance in elite athletes after non-operative treatment of full-thickness proximal hamstring tendon avulsion injuries as well as provide detailed description of the rehabilitation process and provide a mechanobiological hypothesis on processes leading to successful outcomes.

Defining normative side-to-side differences in the distal tibiofibular joint of healthy individuals using weight-bearing CT 3D image analysis.

Background And Purpose: Accurate quantification of bony malalignment within the ankle syndesmosis is crucial in diagnosing syndesmotic instability, especially when subtle. While three-dimensional (3D) measurement techniques using weight-bearing computed tomography (WBCT) have gained popularity, normative bilateral comparative data still need to be established. This study aimed to identify the side-to-side variations and gender differences in the syndesmotic area and volume among individuals without syndesmotic injury using WBCT.

Investigating skeletal muscle micro-trauma with time-dependent diffusion and the random permeable barrier model.

Repeated muscle micro-trauma may cause severe muscle damage. Diffusion tensor imaging (DTI) exhibits sensitivity to microstructural changes in skeletal muscle. We hypothesize that longer diffusion times enhance sensitivity to micro-trauma and that membrane permeability increases with micro-trauma.

3.0-Tesla MRI Observation at Return to Play After Hamstring Injuries.

Objective: To describe 3.0-Tesla (T) magnetic resonance imaging (MRI) findings of hamstring muscles in clinically recovered athletes who were cleared for return to play (RTP).

Design: Prospective observational study.

Acid sphingomyelinase deficiency and Gaucher disease in adults: Similarities and differences in two macrophage storage disorders.

The lysosomal storage diseases chronic visceral acid sphingomyelinase deficiency (ASMD) and Gaucher disease type 1 (GD1) are both macrophage storage disorders with overlapping clinical manifestations. We compared cross-sectional data on visceral, hematological, and biochemical manifestations of untreated adult patients with chronic visceral ASMD ( = 19) and GD1 ( = 85). Spleen volume, liver volume, and bone marrow fat fraction did not significantly differ between the two disease groups ( >0.

Correction: A diffusion tensor-based method facilitating volumetric assessment of fiber orientations in skeletal muscle.

[This corrects the article DOI: 10.1371/journal.pone.

[How well does artificial intelligence detect fractures in the cervical spine on CT?].

Objective: To compare diagnostic accuracy of artificial intelligence (AI) for cervical spine (C-spine) fracture detection on CT with attending radiologists.

Design: Retrospective, diagnostic accuracy study.

Methods: AI analyzed 2368 scans from patients screened for C-spine fracture with CT (2007-2014, fracture prevalence 9.

Does regional implementation of a clinical pathway for older adult patients with pelvic fragility fractures after low-energy trauma improve patient outcomes (PELVIC): a multicentre, stepped-wedge, randomised controlled trial.

Introduction: Patients with pelvic fragility fractures suffer from high morbidity and mortality rates. Despite the high incidence, there is currently no regional or nationwide treatment protocol which results in a wide variety of clinical practices. Recently, there have been new insights into treatment strategies, such as early diagnosis and minimally invasive operative treatment.

Imaging of Juvenile Idiopathic Arthritis.

MRI, ultrasound, and conventional radiography each play distinct roles in the evaluation of juvenile idiopathic arthritis (JIA), with MRI being the preferred imaging modality of choice for assessing both inflammatory and destructive changes. These various imaging modalities provide valuable insights into JIA in pediatric patients. However, challenges persist in terms of achieving precision, ensuring validity, and distinguishing between pathologic findings and normal anatomic variations.

Assessment of bone marrow edema on dual-energy CT scans in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy.

Objective: This study aimed to quantitatively assess the diagnostic value of bone marrow edema (BME) detection on virtual non-calcium (VNCa) images calculated from dual-energy CT (DECT) in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy (CN).

Materials And Methods: People with diabetes mellitus and suspected CN who underwent DECT of the feet (80kVp/Sn150kVp) were included retrospectively. Two blinded observers independently measured CT values on VNCa images using circular regions of interest in five locations in the midfoot (cuneiforms, cuboid and navicular) and the calcaneus of the contralateral or (if one foot was available) the ipsilateral foot.

Automation improves the efficiency of weightbearing CT scan 3D volumetric assessments of the syndesmosis.

Background: Weight-bearing CT (WBCT) 3D volumetric measurement has shown promising accuracy for the diagnosis of syndesmotic instability. However, these measurements are rather complex and time-consuming, rendering them a clinically unfavorable option. We hypothesized that automatized measurements would be more accurate and time-efficient than manual ones.

Postoperative Magnetic Resonance Imaging after Anterior Cruciate Ligament Reconstruction: An Overview and Practical Step-by-step Guide.

Anterior cruciate ligament (ACL) rupture is a frequently encountered injury among athletes, often requiring surgical intervention to restore knee stability. Magnetic resonance imaging (MRI) after ACL reconstruction is common, especially in the evaluation of clinical complications leading to knee instability, decreased range of motion, or pain. This article provides a detailed overview of normal and abnormal postoperative findings including a practical step-by-step guide for MRI assessment.

Extranodal natural killer/T cell lymphoma of the skeletal muscle.

This case report highlights a case of extranodal NK/T cell lymphoma initially misdiagnosed as myositis, emphasizing the appearance on both MRI and FDG PET images. The patient presented with systemic symptoms and calf muscle swelling, prompting imaging studies that revealed diffuse muscle involvement. Despite negative myositis markers and inconclusive biopsy, post-amputation findings confirmed lymphoma with EBV positivity.