Publications by authors named "Bobby A Runderkamp"

Ultra-high field MRI facilitates imaging at high spatial resolutions, which may become important for detailed anatomical and pathological assessment of the human liver. Therefore, we aimed to advance structural liver imaging at 7 T by implementing a high-resolution, phase-shimmed, free-breathing liver scan. Six healthy participants underwent liver MRI scans at 7 T, utilizing an eight-channel parallel transmission system for phase shimming.

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This study aimed to obtain high-resolution 3D isotropic turbo spin-echo (TSE) wrist MRI acquisitions at 7T, with and without fat suppression, facilitated by compressed-sensing (CS) acceleration. In 16 healthy subjects, fat-suppressed (FS) and nonfat-suppressed (NFS) TSE wrist images were obtained. The protocol consisted of a SENSE-accelerated scan, with an isotropic voxel size of 0.

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Methods for early treatment response evaluation to systemic therapy of liver metastases are lacking. Tumor tissue often exhibits an increased ratio of phosphomonoesters to phosphodiesters (PME/PDE), which can be noninvasively measured by phosphorus magnetic resonance spectroscopy (P MRS), and may be a marker for early therapy response assessment in liver metastases. However, with commonly used P surface coils for liver P MRS, the liver is not fully covered, and metastases may be missed.

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Article Synopsis
  • The study aims to achieve consistent imaging signals throughout the human liver using 7 Tesla (7T) MRI, particularly through a technique called flip angle (FA) shimming that utilizes subject-specific data.
  • Researchers evaluated different methods for mapping the FA and found that using 13 phase-encoding steps with a k-point pulse technique provided superior image homogeneity compared to other methods like phase shimming and circularly polarized mode.
  • The conclusion of the study is that high-quality, uniform liver images can be successfully captured with an eight-channel k-point pulse approach based on individual patient data from Fourier PE-DREAM mapping.
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